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    PTGS2 prostaglandin-endoperoxide synthase 2 [ Homo sapiens (human) ]

    Gene ID: 5743, updated on 5-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Relation between ABCB1 overexpression and COX2 and ALOX5 genes in human erythroleukemia cell lines.

    Relation between ABCB1 overexpression and COX2 and ALOX5 genes in human erythroleukemia cell lines.
    Salgado MTSF, Lopes AC, Fernandes E Silva E, Cardoso JQ, Vidal RS, Cavalcante-Silva LHA, Carvalho DCM, Machado KDS, Rodrigues-Mascarenhas S, Rumjanek VM, Votto APS.

    08/26/2024
    Association between vertebral endplate defects and patient-reported symptoms: an immunohistochemical study investigating the COX-2/PGE-2/EP-4 axis.

    Association between vertebral endplate defects and patient-reported symptoms: an immunohistochemical study investigating the COX-2/PGE-2/EP-4 axis.
    Chen H, Zhou Q, Pu X, Wang N, Wang S, Feng Z, Wang B, Zhu Z, Qiu Y, Sun X.

    08/16/2024
    Integration of single-cell RNA sequencing of endothelial cells and proteomics to unravel the role of ICAM1-PTGS2 communication in apical periodontitis: A laboratory investigation.

    Integration of single-cell RNA sequencing of endothelial cells and proteomics to unravel the role of ICAM1-PTGS2 communication in apical periodontitis: A laboratory investigation.
    Lv X, Luo C, Wu J, Huang Y, Quan J, Gong Q, Tong Z.

    08/15/2024
    Breast volume in non-obese females is related to breast adipose cell hypertrophy, inflammation, and COX2 expression.

    Breast volume in non-obese females is related to breast adipose cell hypertrophy, inflammation, and COX2 expression.
    Gogg S, Nerstedt A, Smith U, Hansson E.

    07/13/2024
    RUNX1-induced upregulation of PTGS2 enhances cell growth, migration and invasion in colorectal cancer cells.

    RUNX1-induced upregulation of PTGS2 enhances cell growth, migration and invasion in colorectal cancer cells.
    Zheng W, Guo Y, Kahar A, Bai J, Zhu Q, Huang X, Li Y, Xu B, Jia X, Wu G, Zhang C, Zhu Y., Free PMC Article

    05/30/2024
    Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1alpha Activity in Ishikawa and HEC1a Cells.

    Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells.
    Okumura T, Raja Xavier JP, Pasternak J, Yang Z, Hang C, Nosirov B, Singh Y, Admard J, Brucker SY, Kommoss S, Takeda S, Staebler A, Lang F, Salker MS., Free PMC Article

    05/21/2024
    [The relationship between the expression of PGE2 and COX-2 and the osteogenic activity and oxygen level of alveolar bone].

    [The relationship between the expression of PGE2 and COX-2 and the osteogenic activity and oxygen level of alveolar bone].
    Su JJ, Chen HT, Wang X, Jin Q, Wang L.

    04/10/2024
    The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts.

    The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts.
    Shieh JM, Tsai YJ, Ma MC, Chen CL, Wu WB., Free PMC Article

    04/2/2024
    Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency - a systematic review and integrated bioinformatic analysis.

    Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency - a systematic review and integrated bioinformatic analysis.
    Faizal AM, Elias MH, Jin NM, Abu MA, Syafruddin SE, Zainuddin AA, Suzuki N, Karim AKA., Free PMC Article

    03/27/2024
    Expression of PTGS2 along with genes regulating VEGF signalling pathway and association with high-risk factors in locally advanced oral squamous cell carcinoma.

    Expression of PTGS2 along with genes regulating VEGF signalling pathway and association with high-risk factors in locally advanced oral squamous cell carcinoma.
    Kamal MV, Damerla RR, Parida P, Rao M, Belle VS, Dikhit PS, Palod A, Gireesh R, Kumar NA., Free PMC Article

    03/5/2024
    Mutation of the cyclooxygenase 2 gene promoter and anastomotic leakage in colorectal cancer patients: retrospective cohort study.

    Mutation of the cyclooxygenase 2 gene promoter and anastomotic leakage in colorectal cancer patients: retrospective cohort study.
    Grahn O, Holmgren K, Hong MG, Sund M, Rutegård M., Free PMC Article

    03/1/2024
    Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorspheres Derived from TMZ-Resistant Glioblastoma Cell Lines and Primary Cultures.

    Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorspheres Derived from TMZ-Resistant Glioblastoma Cell Lines and Primary Cultures.
    Lombardi F, Augello FR, Artone S, Ciafarone A, Topi S, Cifone MG, Cinque B, Palumbo P., Free PMC Article

    02/16/2024
    Endometrial receptivity defects MUC-1 and COX-2 polymorphisms in endometriosis.

    Endometrial receptivity defects MUC-1 and COX-2 polymorphisms in endometriosis.
    Budihastuti UR, Dasuki D, Sadewa AH, Utoro T., Free PMC Article

    02/6/2024
    The expression of p53, ki67 and COX-2 in erosive-type oral lichen planus.

    The expression of p53, ki67 and COX-2 in erosive-type oral lichen planus.
    Aziz S, Hamad S, Qasim Y.

    01/5/2024
    Regulatory action of PGRMC1 on cyclic AMP-mediated COX2 expression in human endometrial cells.

    Regulatory action of PGRMC1 on cyclic AMP-mediated COX2 expression in human endometrial cells.
    Tsuru A, Yoshie M, Negishi R, Mukoyama T, Yonekawa R, Kojima J, Azumi M, Kusama K, Nishi H, Tamura K.

    11/30/2023
    KIAA1429 Promotes Nasopharyngeal Carcinoma Progression by Mediating m6A Modification of PTGS2.

    KIAA1429 Promotes Nasopharyngeal Carcinoma Progression by Mediating m6A Modification of PTGS2.
    Wu L, Zhou Y, Fu J.

    11/28/2023
    CFAP61 knockdown aggravates male infertility by inhibiting testosterone secretion by Leydig cells via the MAPK/COX-2 pathway.

    CFAP61 knockdown aggravates male infertility by inhibiting testosterone secretion by Leydig cells via the MAPK/COX-2 pathway.
    Zhu W, Mao J, Qin J, Chen X.

    11/22/2023
    Changes and clinical significance of serum MMP-9, TIMP-1, COX-2, and immune levels in patients with asthma.

    Changes and clinical significance of serum MMP-9, TIMP-1, COX-2, and immune levels in patients with asthma.
    Ming H, Huang Y, Mao J, Wang H, Gao X, Li Z.

    11/14/2023
    Thrombin-Induced COX-2 Expression and PGE2 Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCdelta/Pyk2-Dependent AP-1 Pathway Modulation.

    Thrombin-Induced COX-2 Expression and PGE(2) Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCδ/Pyk2-Dependent AP-1 Pathway Modulation.
    Yang CC, Lee IT, Lin YJ, Wu WB, Hsiao LD, Yang CM., Free PMC Article

    10/30/2023
    ER and COX2 expression in endometrial hyperplasia processes.

    ER and COX2 expression in endometrial hyperplasia processes.
    Tsyndrenko N, Lyndіn M, Sikora K, Wireko AA, Abdul-Rahman T, Hyriavenko N, Romaniuk A., Free PMC Article

    08/25/2023
    Expression and correlation of COX-2 and NUCB1 in colorectal adenocarcinoma.

    Expression and correlation of COX-2 and NUCB1 in colorectal adenocarcinoma.
    Zhang Y, Zhang G, Zhong J, Li A, Wu Y, Guo Z., Free PMC Article

    08/9/2023
    Association of cyclooxygenase-2 expression with endoplasmic reticulum stress and autophagy in triple-negative breast cancer.

    Association of cyclooxygenase-2 expression with endoplasmic reticulum stress and autophagy in triple-negative breast cancer.
    Lee H, Jung S, Gong G, Lim B, Lee HJ., Free PMC Article

    08/7/2023
    Plasma Cyclooxygenase-2 as a Potential Biomarker for Early Diagnosis of Kawasaki Disease.

    Plasma Cyclooxygenase-2 as a Potential Biomarker for Early Diagnosis of Kawasaki Disease.
    Li S, Yang Z.

    07/31/2023
    Immunohistochemical evaluation of cyclooxygenase-2 and mast cell density in periapical lesions.

    Immunohistochemical evaluation of cyclooxygenase-2 and mast cell density in periapical lesions.
    Malik S, Kamboj M, Narwal A, Devi A.

    07/13/2023
    ERBB2-PTGS2 axis promotes intervertebral disc degeneration by regulating senescence of nucleus pulposus cells.

    ERBB2-PTGS2 axis promotes intervertebral disc degeneration by regulating senescence of nucleus pulposus cells.
    Li ZC, An F., Free PMC Article

    06/28/2023
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