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    CORO1B coronin 1B [ Homo sapiens (human) ]

    Gene ID: 57175, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis.

    Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis.
    Hachimi M, Grabowski C, Campanario S, Herranz G, Baonza G, Serrador JM, Gomez-Lopez S, Barea MD, Bosch-Fortea M, Gilmour D, Bagnat M, Rodriguez-Fraticelli AE, Martin-Belmonte F., Free PMC Article

    01/29/2022
    Coronin 1B regulates the TNFalpha-induced apoptosis of HUVECs by mediating the interaction between TRADD and FADD.

    Coronin 1B regulates the TNFα-induced apoptosis of HUVECs by mediating the interaction between TRADD and FADD.
    Kim GY, Lim HJ, Kim WH, Park HY.

    11/28/2020
    VEGF-activated p38alpha phosphorylates coronin 1B at Ser2 and activates the Arp2/3 complex by liberating it from coronin 1B.

    Coronin 1B serine 2 phosphorylation by p38α is critical for vascular endothelial growth factor-induced migration of human umbilical vein endothelial cells.
    Kim GY, Park JH, Kim H, Lim HJ, Park HY.

    09/30/2017
    Coronin 1B constitutively binds to TGF beta receptor I in vascular smooth muscle cells.

    Binding of coronin 1B to TβRI negatively regulates the TGFβ1 signaling pathway.
    Kim GY, Lim HJ, Park HY.

    08/5/2017
    The loss of junctional NMIIA, upon Coronin 1B knockdown, perturbed RhoA signaling.

    Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II.
    Priya R, Wee K, Budnar S, Gomez GA, Yap AS, Michael M., Free PMC Article

    06/24/2017
    When cells undergo apoptosis in an epithelial monolayer, coronin 1B is recruited to the junctional cortex at apoptotic/neighbor cell interface in an E-cadherin-dependent fashion to support actin architectural reorganization, contractility, and extrusion.

    Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions.
    Michael M, Meiring JCM, Acharya BR, Matthews DR, Verma S, Han SP, Hill MM, Parton RG, Gomez GA, Yap AS.

    08/20/2016
    Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis.

    Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction.
    Usatyuk PV, Burns M, Mohan V, Pendyala S, He D, Ebenezer DL, Harijith A, Fu P, Huang LS, Bear JE, Garcia JG, Natarajan V., Free PMC Article

    12/21/2013
    analysis of the mechanism for negatively regulating Rho-kinase (ROCK) signaling through Coronin1B protein in neuregulin 1 (NRG-1)-induced tumor cell motility

    Novel mechanism for negatively regulating Rho-kinase (ROCK) signaling through Coronin1B protein in neuregulin 1 (NRG-1)-induced tumor cell motility.
    Rana MK, Worthylake RA., Free PMC Article

    09/22/2012
    Coronin 1B regulates leading edge dynamics and controls cell motility and interactions with the actin-related protein (Arp)2/3 complex

    Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility.
    Cai L, Holoweckyj N, Schaller MD, Bear JE.

    01/21/2010
    Study concludes that Coronin 1B's coordination of filament formation by Arp2/3 complex and filament turnover by Cofilin is required for effective lamellipodial protrusion and cell migration.

    Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge.
    Cai L, Marshall TW, Uetrecht AC, Schafer DA, Bear JE., Free PMC Article

    01/21/2010
    In rabbits, cholinergic stimulation increases the phosphorylation of coronin 1B in gastric mucosal cells

    Isolation, cloning, and characterization of a new mammalian coronin family member, coroninse, which is regulated within the protein kinase C signaling pathway.
    Parente JA Jr, Chen X, Zhou C, Petropoulos AC, Chew CS.

    07/23/2004
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