| Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis. | Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis.
Lun J, Zhang Y, Yu M, Zhai W, Zhu L, Liu H, Guo J, Zhang G, Qiu W, Fang J. | 07/10/2024 |
| Decreased DNA Methylation of RGMA is Associated with Intracranial Hypertension After Severe Traumatic Brain Injury: An Exploratory Epigenome-Wide Association Study. | Decreased DNA Methylation of RGMA is Associated with Intracranial Hypertension After Severe Traumatic Brain Injury: An Exploratory Epigenome-Wide Association Study.
Liu D, Zusman BE, Shaffer JR, Li Y, Arockiaraj AI, Liu S, Weeks DE, Desai SM, Kochanek PM, Puccio AM, Okonkwo DO, Conley YP, Jha RM., Free PMC Article | 09/3/2022 |
| Repulsive Guidance Molecule-a and Central Nervous System Diseases. | Repulsive Guidance Molecule-a and Central Nervous System Diseases.
Tang J, Zeng X, Li H, Ju L, Feng J, Yang J., Free PMC Article | 06/26/2021 |
| MicroRNA-4472 Promotes Tumor Proliferation and Aggressiveness in Breast Cancer by Targeting RGMA and Inducing EMT. | MicroRNA-4472 Promotes Tumor Proliferation and Aggressiveness in Breast Cancer by Targeting RGMA and Inducing EMT.
Li Y, Wang YW, Chen X, Ma RR, Guo XY, Liu HT, Jiang SJ, Wei JM, Gao P. | 04/3/2021 |
| a regulatory variant of RGMA is associated with opioid dependence in European Americans | Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.
Cheng Z, Zhou H, Sherva R, Farrer LA, Kranzler HR, Gelernter J., Free PMC Article | 10/19/2019 |
| RGMA is regulated by the HIF1A/miR-210 axis and inhibits oral squamous cell carcinoma. | Downregulation of RGMA by HIF-1A/miR-210-3p axis promotes cell proliferation in oral squamous cell carcinoma.
Lu Y, Li Y, Wang Z, Xie S, Wang Q, Lei X, Ruan Y, Li J. | 07/27/2019 |
| Dysregulation of RGMa plays an important role in the pathology of Parkinson's disease. | Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease.
Korecka JA, Moloney EB, Eggers R, Hobo B, Scheffer S, Ras-Verloop N, Pasterkamp RJ, Swaab DF, Smit AB, van Kesteren RE, Bossers K, Verhaagen J., Free PMC Article | 10/14/2017 |
| Thus, we conclude that RGMa inhibits angiogenesis in vitro and in vivo suggesting that its manipulation would be an efficient therapeutic strategy for pro-angiogenic conditions. | Repulsive guidance molecule A suppresses angiogenesis.
Harada K, Fujita Y, Yamashita T. | 05/28/2016 |
| RGMa expression and promoter methylation status are closely related to colorectal cancer genesis and progression. | Decreased expression of repulsive guidance molecule member A by DNA methylation in colorectal cancer is related to tumor progression.
Zhao ZW, Lian WJ, Chen GQ, Zhou HY, Wang GM, Cao X, Yang HJ, Hou YP. | 07/28/2012 |
| identification of neogenin-binding site on the repulsive guidance molecule A | Identification of the neogenin-binding site on the repulsive guidance molecule A.
Itokazu T, Fujita Y, Takahashi R, Yamashita T., Free PMC Article | 07/28/2012 |
| The expression of RGMA, RGMB and RGMC was evident in most examined prostate cancer cell lines, and also in the prostate cancer tissues | Repulsive guidance molecules, novel bone morphogenetic protein co-receptors, are key regulators of the growth and aggressiveness of prostate cancer cells.
Li J, Ye L, Kynaston HG, Jiang WG. | 04/7/2012 |
| Reduced expression of RGMA in breast cancer was associated with breast cancer. | Potential prognostic value of repulsive guidance molecules in breast cancer.
Li J, Ye L, Mansel RE, Jiang WG. | 09/3/2011 |
| The full-length signal peptides of RGMa is functional and furthermore that the C-domains are sufficient and essential for ER targeting, whereas the N-domains are dispensable. Thus, the N-domains are available for additional functions. | Long signal peptides of RGMa and DCBLD2 are dissectible into subdomains according to the NtraC model.
Resch E, Hiss JA, Schreiner A, Schneider G, Starzinski-Powitz A. | 08/6/2011 |
| RGM-A is a unique endogenous inhibitor of leukocyte chemotaxis that limits inflammatory leukocyte traffic | Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation.
Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, Köhler D, Skutella T, Meisel C, Brommer B, Rosenberger P, Schwab JM., Free PMC Article | 06/18/2011 |
| Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms. | Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms.
Li VS, Yuen ST, Chan TL, Yan HH, Law WL, Yeung BH, Chan AS, Tsui WY, So S, Chen X, Leung SY. | 01/21/2010 |
| this study, we show that Unc5B, a member of the netrin receptor family, interacts with neogenin as a coreceptor for RGMa. | Unc5B associates with LARG to mediate the action of repulsive guidance molecule.
Hata K, Kaibuchi K, Inagaki S, Yamashita T., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesRGMA and IL21R show association with experimental inflammation and multiple sclerosis.
Nohra R, Beyeen AD, Guo JP, Khademi M, Sundqvist E, Hedreul MT, Sellebjerg F, Smestad C, Oturai AB, Harbo HF, Wallström E, Hillert J, Alfredsson L, Kockum I, Jagodic M, Lorentzen J, Olsson T. Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3.
Verma R, Holmans P, Knowles JA, Grover D, Evgrafov OV, Crowe RR, Scheftner WA, Weissman MM, DePaulo JR Jr, Potash JB, Levinson DF. | 04/16/2008 |
| detected a homozygous deletion of chromosomal region 15q26.2 in the cell line HDLM2 encompasing RGMA and CHD2 | A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines.
Feys T, Poppe B, De Preter K, Van Roy N, Verhasselt B, De Paepe P, De Paepe A, Speleman F. | 01/21/2010 |
| RGMa facilitates the use of ActRIIA by endogenous BMP2 and BMP4 ligands that otherwise prefer signaling via BMPRII and increased utilization of ActRIIA leads to generation of an enhanced BMP signal | Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4.
Xia Y, Yu PB, Sidis Y, Beppu H, Bloch KD, Schneyer AL, Lin HY. | 01/21/2010 |
| Following central nervous system injury, RGM, a novel, potent axonal growth inhibitor, is present in axonal growth impediments: the mature myelin, choroid plexus, and components of the developing scar. | Central nervous system injury-induced repulsive guidance molecule expression in the adult human brain.
Schwab JM, Monnier PP, Schluesener HJ, Conrad S, Beschorner R, Chen L, Meyermann R, Mueller BK. | 01/21/2010 |