| Endogenous ZAP affects Zika virus RNA interactome. | Endogenous ZAP affects Zika virus RNA interactome.
Sabir AJ, Le NPK, Singh PP, Karniychuk U., Free PMC Article | 08/31/2024 |
| Association of ZC3HAV1 single nucleotide polymorphisms with the susceptibility of Vogt-Koyanagi-Harada Disease. | Association of ZC3HAV1 single nucleotide polymorphisms with the susceptibility of Vogt-Koyanagi-Harada Disease.
Wu Q, Zhong Z, Zhou C, Cao Q, Su G, Yang P., Free PMC Article | 05/31/2023 |
| Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist. | Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist.
Okudera M, Odawara M, Arakawa M, Kawaguchi S, Seya K, Matsumiya T, Sato R, Ding J, Morita E, Imaizumi T. | 01/7/2023 |
| ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition. | ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition.
Ly PT, Xu S, Wirawan M, Luo D, Roca X., Free PMC Article | 08/13/2022 |
| The low abundance of CpG in the SARS-CoV-2 genome is not an evolutionarily signature of ZAP. | The low abundance of CpG in the SARS-CoV-2 genome is not an evolutionarily signature of ZAP.
Afrasiabi A, Alinejad-Rokny H, Khosh A, Rahnama M, Lovell N, Xu Z, Ebrahimi D., Free PMC Article | 03/5/2022 |
| Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets. | Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets.
Rodriguez KM, Buch-Larsen SC, Kirby IT, Siordia IR, Hutin D, Rasmussen M, Grant DM, David LL, Matthews J, Nielsen ML, Cohen MS., Free PMC Article | 02/5/2022 |
| ZC3HAV1 promotes the proliferation and metastasis via regulating KRAS in pancreatic cancer. | ZC3HAV1 promotes the proliferation and metastasis via regulating KRAS in pancreatic cancer.
Huang W, Hua H, Xiao G, Yang X, Yang Q, Jin L., Free PMC Article | 12/11/2021 |
| The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral UL4/UL5 Transcripts. | The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral UL4/UL5 Transcripts.
Gonzalez-Perez AC, Stempel M, Wyler E, Urban C, Piras A, Hennig T, Ganskih S, Wei Y, Heim A, Landthaler M, Pichlmair A, Dölken L, Munschauer M, Erhard F, Brinkmann MM., Free PMC Article | 10/16/2021 |
| Association of Zinc Finger Antiviral Protein Binding to Viral Genomic RNA with Attenuation of Replication of Echovirus 7. | Association of Zinc Finger Antiviral Protein Binding to Viral Genomic RNA with Attenuation of Replication of Echovirus 7.
Goonawardane N, Nguyen D, Simmonds P., Free PMC Article | 08/21/2021 |
| The Interaction of Human and Epstein-Barr Virus miRNAs with Multiple Sclerosis Risk Loci. | The Interaction of Human and Epstein-Barr Virus miRNAs with Multiple Sclerosis Risk Loci.
Afrasiabi A, Fewings NL, Schibeci SD, Keane JT, Booth DR, Parnell GP, Swaminathan S., Free PMC Article | 04/24/2021 |
| Coronavirus genomes carry the signatures of their habitats. | Coronavirus genomes carry the signatures of their habitats.
Wei Y, Silke JR, Aris P, Xia X., Free PMC Article | 01/9/2021 |
| SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans. | SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans.
Nchioua R, Kmiec D, Müller JA, Conzelmann C, Groß R, Swanson CM, Neil SJD, Stenger S, Sauter D, Münch J, Sparrer KMJ, Kirchhoff F., Free PMC Article | 11/21/2020 |
| Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene. | Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene.
Lin YT, Chiweshe S, McCormick D, Raper A, Wickenhagen A, DeFillipis V, Gaunt E, Simmonds P, Wilson SJ, Grey F., Free PMC Article | 10/24/2020 |
| Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells. | Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells.
Peng C, Wyatt LS, Glushakow-Smith SG, Lal-Nag M, Weisberg AS, Moss B., Free PMC Article | 10/10/2020 |
| CpG Frequency in the 5' Third of the env Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein. | CpG Frequency in the 5' Third of the env Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein.
Kmiec D, Nchioua R, Sherrill-Mix S, Stürzel CM, Heusinger E, Braun E, Gondim MVP, Hotter D, Sparrer KMJ, Hahn BH, Sauter D, Kirchhoff F., Free PMC Article | 09/19/2020 |
| CpG Dinucleotides Inhibit HIV-1 Replication through Zinc Finger Antiviral Protein (ZAP)-Dependent and -Independent Mechanisms. | CpG Dinucleotides Inhibit HIV-1 Replication through Zinc Finger Antiviral Protein (ZAP)-Dependent and -Independent Mechanisms.
Ficarelli M, Antzin-Anduetza I, Hugh-White R, Firth AE, Sertkaya H, Wilson H, Neil SJD, Schulz R, Swanson CM., Free PMC Article | 09/5/2020 |
| This is the first study that defines the antiviral capacities of individual ZAP isoforms in the absence of endogenous ZAP expression and, hence, cross talk with other isoforms. Data demonstrate that ZAP is expressed as four different forms: ZAPS, ZAPM, ZAPL, and ZAPXL. | Characterization of Novel Splice Variants of Zinc Finger Antiviral Protein (ZAP).
Li MMH, Aguilar EG, Michailidis E, Pabon J, Park P, Wu X, de Jong YP, Schneider WM, Molina H, Rice CM, MacDonald MR., Free PMC Article | 07/11/2020 |
| there was a dose-dependent reduction in virus production with ZAP expression | HTLV-1 contains a high CG dinucleotide content and is susceptible to the host antiviral protein ZAP.
Miyazato P, Matsuo M, Tan BJY, Tokunaga M, Katsuya H, Islam S, Ito J, Murakawa Y, Satou Y., Free PMC Article | 05/23/2020 |
| ZAP 4 zinc fingers create a basic patch on the ZAP RNA-binding domain surface.ZAP crystal structure explains how ZAP is able to specifically recognize foreign, CG-rich viral RNA. | Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences.
Meagher JL, Takata M, Gonçalves-Carneiro D, Keane SC, Rebendenne A, Ong H, Orr VK, MacDonald MR, Stuckey JA, Bieniasz PD, Smith JL., Free PMC Article | 05/2/2020 |
| KHNYN as a novel cofactor for ZAP to target CpG-containing retroviral RNA for degradation. | KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides.
Ficarelli M, Wilson H, Pedro Galão R, Mazzon M, Antzin-Anduetza I, Marsh M, Neil SJ, Swanson CM., Free PMC Article | 02/29/2020 |
| this study shows that RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions | RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions.
Schwerk J, Soveg FW, Ryan AP, Thomas KR, Hatfield LD, Ozarkar S, Forero A, Kell AM, Roby JA, So L, Hyde JL, Gale M Jr, Daugherty MD, Savan R., Free PMC Article | 02/29/2020 |
| The dependence on expression of ZAP antiviral protein (ZAP), 2'-5'-oligoadenylate synthetase (OAS3) and 2-5A-dependent ribonuclease (RNAseL) for CpG/UpA-mediated attenuation and the variable and often low level expression of these pathway proteins in certain cell types. | The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides.
Odon V, Fros JJ, Goonawardane N, Dietrich I, Ibrahim A, Alshaikhahmed K, Nguyen D, Simmonds P., Free PMC Article | 12/14/2019 |
| ZAP may act as an intrinsic antiviral factor through specific RNA binding to fight against Japanese encephalitis virus infection | Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein.
Chiu HP, Chiu H, Yang CF, Lee YL, Chiu FL, Kuo HC, Lin RJ, Lin YL., Free PMC Article | 01/19/2019 |
| results indicate that low ZAP expression is common in hepatocellular carcinoma (HCC), is correlated with the progression of HCC and with a poorer prognosis for HCC patients, and plays an important role in HCC carcinogenesis | Association of Low Zinc Finger Antiviral Protein Expression with Progression and Poor Survival of Patients with Hepatocellular Carcinoma.
Liu Y, Hu C, Zhu WB, Xu WX, Li ZY, Lin Y, Cai J, Liang JK, Zhu X, Gao ZL, Yan GM, Peng L. | 12/8/2018 |
| In response to DNA damage, activated and auto-poly-ADP-ribosylated PARP1 dissociates from HSF1-PARP13, and redistributes to DNA lesions and DNA damage-inducible gene loci. | The HSF1-PARP13-PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis.
Fujimoto M, Takii R, Takaki E, Katiyar A, Nakato R, Shirahige K, Nakai A., Free PMC Article | 10/6/2018 |