| Raised CK and acute kidney injury following intense exercise in three patients with a history of exercise intolerance due to homozygous mutations in SLC2A9. | Raised CK and acute kidney injury following intense exercise in three patients with a history of exercise intolerance due to homozygous mutations in SLC2A9.
Quinlivan R, Murphy E, Pula S, Pain A, Brain H, Scopes G, Gjika F, Ahmadouk N, Manole A, Houlden H. | 01/29/2024 |
| GLUT9 as a potential drug target for chronic kidney disease: Drug target validation by a Mendelian randomization study. | GLUT9 as a potential drug target for chronic kidney disease: Drug target validation by a Mendelian randomization study.
Ueda M, Fukui K, Kamatani N, Kamitsuji S, Matsuo A, Sasase T, Nishiu J, Matsushita M. | 11/8/2023 |
| Pathogenic Variants of SLC22A12 (URAT1) and SLC2A9 (GLUT9) in Spanish Patients with Renal Hypouricemia: Founder Effect of SLC2A9 Variant c.374C>T; p.(T125M). | Pathogenic Variants of SLC22A12 (URAT1) and SLC2A9 (GLUT9) in Spanish Patients with Renal Hypouricemia: Founder Effect of SLC2A9 Variant c.374C>T; p.(T125M).
Perdomo-Ramirez A, Cordoba-Lanus E, Trujillo-Frias CJ, Gonzalez-Navasa C, Ramos-Trujillo E, Luis-Yanes MI, Garcia-Nieto V, Claverie-Martin F, RenalTube., Free PMC Article | 05/15/2023 |
| The in-silico evaluation of important GLUT9 residue for uric acid transport based on renal hypouricemia type 2. | The in-silico evaluation of important GLUT9 residue for uric acid transport based on renal hypouricemia type 2.
Cachau R, Shahsavari S, Cho SK., Free PMC Article | 03/3/2023 |
| The regulation effect of GLUT9/SLC2A9 on intrahepatic uric acid level and metabolic associated fatty liver disease. | The regulation effect of GLUT9/SLC2A9 on intrahepatic uric acid level and metabolic associated fatty liver disease.
Zeng H, Tang C, Lin B, Yu M, Wang X, Wang J, Chen S, Yu C. | 10/15/2022 |
| Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System. | Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System.
Lüscher BP, Albrecht C, Stieger B, Surbek DV, Baumann MU., Free PMC Article | 04/16/2022 |
| The effects of hyperuricemia on endothelial cells are mediated via GLUT9 and the JAK2/STAT3 pathway. | The effects of hyperuricemia on endothelial cells are mediated via GLUT9 and the JAK2/STAT3 pathway.
Nie Q, Liu M, Zhang Z, Zhang X, Wang C, Song G., Free PMC Article | 03/5/2022 |
| Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. | Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus.
Tin A, Schlosser P, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Yu Z, Weihs A, Hoppmann A, Grundner-Culemann F, Min JL, Kuhns VLH, Adeyemo AA, Agyemang C, Ärnlöv J, Aziz NA, Baccarelli A, Bochud M, Brenner H, Bressler J, Breteler MMB, Carmeli C, Chaker L, Coresh J, Corre T, Correa A, Cox SR, Delgado GE, Eckardt KU, Ekici AB, Endlich K, Floyd JS, Fraszczyk E, Gao X, Gào X, Gelber AC, Ghanbari M, Ghasemi S, Gieger C, Greenland P, Grove ML, Harris SE, Hemani G, Henneman P, Herder C, Horvath S, Hou L, Hurme MA, Hwang SJ, Kardia SLR, Kasela S, Kleber ME, Koenig W, Kooner JS, Kronenberg F, Kühnel B, Ladd-Acosta C, Lehtimäki T, Lind L, Liu D, Lloyd-Jones DM, Lorkowski S, Lu AT, Marioni RE, März W, McCartney DL, Meeks KAC, Milani L, Mishra PP, Nauck M, Nowak C, Peters A, Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Schöttker B, Schwartz J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S, Sundström J, Swenson BR, van Meurs JBJ, van Vliet-Ostaptchouk JV, Venema A, Völker U, Winkelmann J, Wolffenbuttel BHR, Zhao W, Zheng Y, Estonian Biobank Research Team, Genetics of DNA Methylation Consortium, Loh M, Snieder H, Waldenberger M, Levy D, Akilesh S, Woodward OM, Susztak K, Teumer A, Köttgen A., Free PMC Article | 01/22/2022 |
| The haplotype of SLC2A9_rs3733591, PKD2_rs2725220 and ABCG2_rs2231142 increases the hyperuricaemia risk and alcohol, chicken and processed meat intakes and smoking interact with its risk. | The haplotype of SLC2A9_rs3733591, PKD2_rs2725220 and ABCG2_rs2231142 increases the hyperuricaemia risk and alcohol, chicken and processed meat intakes and smoking interact with its risk.
Yang HJ, Liu M, Kim MJ, Park S. | 10/16/2021 |
| Renal Reabsorptive Transport of Uric Acid Precursor Xanthine by URAT1 and GLUT9. | Renal Reabsorptive Transport of Uric Acid Precursor Xanthine by URAT1 and GLUT9.
Arakawa H, Amezawa N, Kawakatsu Y, Tamai I. | 07/17/2021 |
| Trans-ancestral dissection of urate- and gout-associated major loci SLC2A9 and ABCG2 reveals primate-specific regulatory effects. | Trans-ancestral dissection of urate- and gout-associated major loci SLC2A9 and ABCG2 reveals primate-specific regulatory effects.
Takei R, Cadzow M, Markie D, Bixley M, Phipps-Green A, Major TJ, Li C, Choi HK, Li Z, Hu H, Eurogout Consortium, Guo H, He M, Shi Y, Stamp LK, Dalbeth N, Merriman TR, Wei WH. | 07/3/2021 |
| Refining genome-wide associated loci for serum uric acid in individuals with African ancestry. | Refining genome-wide associated loci for serum uric acid in individuals with African ancestry.
Chen G, Shriner D, Doumatey AP, Zhou J, Bentley AR, Lei L, Adeyemo A, Rotimi CN., Free PMC Article | 06/5/2021 |
| Coexistence of autosomal dominant polycystic kidney disease type 1 and hereditary renal hypouricemia type 2: A model of early-onset and fast cyst progression. | Coexistence of autosomal dominant polycystic kidney disease type 1 and hereditary renal hypouricemia type 2: A model of early-onset and fast cyst progression.
Peces R, Mena R, Peces C, Cuesta E, Selgas R, Barruz P, Lapunzina P, Nevado J. | 06/5/2021 |
| The association between genetic polymorphisms in ABCG2 and SLC2A9 and urate: an updated systematic review and meta-analysis. | The association between genetic polymorphisms in ABCG2 and SLC2A9 and urate: an updated systematic review and meta-analysis.
Lukkunaprasit T, Rattanasiri S, Turongkaravee S, Suvannang N, Ingsathit A, Attia J, Thakkinstian A., Free PMC Article | 01/9/2021 |
| MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells in hyperuricemia. | MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Zhou Z, Dong Y, Zhou H, Liu J, Zhao W. | 05/30/2020 |
| Single nucleotide variations ( p.T21I and p.G13D) in SLC2A9 had no significant effects on hyperuricemia susceptibility, while the gene-based analyses substantiated the significant results on hypouricemia. | Amplicon targeted resequencing for SLC2A9 and SLC22A12 identified novel mutations in hypouricemia subjects.
Zhou Z, Wang K, Zhou J, Wang C, Li X, Cui L, Han L, Liu Z, Ren W, Wang X, Zhang K, Li Z, Pan D, Li C, Shi Y., Free PMC Article | 05/23/2020 |
| SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors are modifiers in susceptibility for Hyperuricemia in an elderly community-dwelling population. | ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population.
Liu J, Yang W, Li Y, Wei Z, Dan X., Free PMC Article | 05/9/2020 |
| GLUT9 and URAT1 functioned synergistically to transport urate into the chondrocyte cytoplasm, which was inhibited by specific gene knockdowns and druginduced inhibition. | Urate transport capacity of glucose transporter 9 and urate transporter 1 in cartilage chondrocytes.
Zhang B, Duan M, Long B, Zhang B, Wang D, Zhang Y, Chen J, Huang X, Jiao Y, Zhu L, Zeng X., Free PMC Article | 01/4/2020 |
| association of genetic variant rs3733591 with gout in Malaysia | Association of solute carrier family 2, member 9 (SLC2A9) genetic variant rs3733591 with gout in a Malay sample set.
Wan Rohani WT, Mahfudzah A, Nazihah MY, Tan HL, Wan Syamimee WG, Amanda Jane PG, Tony Richard M. | 11/2/2019 |
| No significant associations between the SNPs in SLC2A9 and Parkinson risk among men or women. | Genetic variants related to urate and risk of Parkinson's disease.
Hughes KC, Gao X, O'Reilly EJ, Kim IY, Wang M, Weisskopf MG, Schwarzschild MA, Ascherio A., Free PMC Article | 09/14/2019 |
| the present study demonstrates that SLC2A9 may be a novel tumor suppressor gene and a potential therapeutic target in hepatocellular carcinoma | Overexpression of Uric Acid Transporter SLC2A9 Inhibits Proliferation of Hepatocellular Carcinoma Cells.
Han X, Yang J, Li D, Guo Z., Free PMC Article | 08/31/2019 |
| Some of these single nucleotide polymorphisms in SLC2A9 may increase the risk of hyperuricemia. | Association between SLC2A9 Genetic Variants and Risk of Hyperuricemia in a Uygur Population.
Sun YP, Xu FL, Yan DD, Mayina Kahaer, Zhang XJ, Guo YY, Hu C, Jia WP, Luo L. | 08/24/2019 |
| Placental expression of at least three GLUT isoforms, i.e. GLUT-1, GLUT-4, and GLUT-9, may be involved in the intensification of intrauterine fetal growth in pregnancies complicated by gestational diabetes mellitus and pregnancy complicated by diabetes mellitus, type 1. | Analysis of correlations between the placental expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 and selected maternal and fetal parameters in pregnancies complicated by diabetes mellitus.
Stanirowski PJ, Szukiewicz D, Pyzlak M, Abdalla N, Sawicki W, Cendrowski K. | 03/23/2019 |
| Findings provide new insights into the genetic architecture of serum urate, and highlight molecular targets in SLC22A12 and SLC2A9 for lowering serum urate and preventing gout. | Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels.
Tin A, Li Y, Brody JA, Nutile T, Chu AY, Huffman JE, Yang Q, Chen MH, Robinson-Cohen C, Macé A, Liu J, Demirkan A, Sorice R, Sedaghat S, Swen M, Yu B, Ghasemi S, Teumer A, Vollenweider P, Ciullo M, Li M, Uitterlinden AG, Kraaij R, Amin N, van Rooij J, Kutalik Z, Dehghan A, McKnight B, van Duijn CM, Morrison A, Psaty BM, Boerwinkle E, Fox CS, Woodward OM, Köttgen A., Free PMC Article | 01/5/2019 |
| Interaction analysis demonstrated that the following genotypes: MS4A14 DI+II, SLC2A DI+II and ABCB 5 CG+GG, were associated with a prothrombin time >/=12 sec and with Recurrent pregnancy loss (RPL) risk | Association study of frameshift and splice variant polymorphisms with risk of idiopathic recurrent pregnancy loss.
Lee HA, Ahn EH, Kim JH, Kim JO, Ryu CS, Lee JY, Cho SH, Lee WS, Kim NK. | 11/3/2018 |