| The Human Intermediate Prolactin Receptor I-tail Contributes Breast Oncogenesis by Targeting Ras/MAPK Pathway. | The Human Intermediate Prolactin Receptor I-tail Contributes Breast Oncogenesis by Targeting Ras/MAPK Pathway.
Shen S, Radhakrishnan SK, Harrell JC, Puchalapalli M, Koblinski J, Clevenger C., | 06/3/2024 |
| The prolactin receptor gene (PRLR) is linked and associated with the risk of polycystic ovarian syndrome. | The prolactin receptor gene (PRLR) is linked and associated with the risk of polycystic ovarian syndrome.
Amin M, Gragnoli C., Free PMC Article | 11/27/2023 |
| The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate. | The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate.
Araya-Secchi R, Bugge K, Seiffert P, Petry A, Haxholm GW, Lindorff-Larsen K, Pedersen SF, Arleth L, Kragelund BB., Free PMC Article | 06/22/2023 |
| PRL-R Variants Are Not Only Associated With Prolactinomas But Also With Dopamine Agonist Resistance. | PRL-R Variants Are Not Only Associated With Prolactinomas But Also With Dopamine Agonist Resistance.
de Castro Moreira AR, Trarbach E, Bueno CBF, Monteiro ALS, Grande IPP, Padula M, Maciel GAR, Glezer A. | 06/22/2023 |
| [Prolactin and its receptor: From animal models to pituitary pathophysiology]. | [Prolactin and its receptor: From animal models to pituitary pathophysiology].
Begon E, Bernard V. | 03/2/2023 |
| Prolactin receptor gene transcriptional control, regulatory modalities relevant to breast cancer resistance and invasiveness. | Prolactin receptor gene transcriptional control, regulatory modalities relevant to breast cancer resistance and invasiveness.
Kavarthapu R, Dufau ML., Free PMC Article | 10/8/2022 |
| Breast Cancer and Prolactin - New Mechanisms and Models. | Breast Cancer and Prolactin - New Mechanisms and Models.
Clevenger CV, Rui H., Free PMC Article | 09/10/2022 |
| Prolactin receptor expression and its role in trophoblast outgrowth in human embryos. | Prolactin receptor expression and its role in trophoblast outgrowth in human embryos.
Ezoe K, Miki T, Ohata K, Fujiwara N, Yabuuchi A, Kobayashi T, Kato K. | 12/4/2021 |
| Upregulation of Prolactin Receptor Expression and Activation of Prolactin Signaling in an Aggressive Triple-Negative Breast Carcinoma During Pregnancy: A Case Report. | Upregulation of Prolactin Receptor Expression and Activation of Prolactin Signaling in an Aggressive Triple-Negative Breast Carcinoma During Pregnancy: A Case Report.
Popnikolov N, Brzezinska K, Platoff RM, Binnebose R, Rothstein-Rubin R, Komarnicky LT, Woodworth A. | 11/6/2021 |
| Immunohistochemical localization of prolactin receptor (PRLR) to Hodgkin's and Reed-Sternberg cells of Hodgkin's lymphoma. | Immunohistochemical localization of prolactin receptor (PRLR) to Hodgkin's and Reed-Sternberg cells of Hodgkin's lymphoma.
Gharbaran R, Onwumere O, Codrington N, Somenarain L, Redenti S. | 10/9/2021 |
| The short isoform of PRLR suppresses the pentose phosphate pathway and nucleotide synthesis through the NEK9-Hippo axis in pancreatic cancer. | The short isoform of PRLR suppresses the pentose phosphate pathway and nucleotide synthesis through the NEK9-Hippo axis in pancreatic cancer.
Nie H, Huang PQ, Jiang SH, Yang Q, Hu LP, Yang XM, Li J, Wang YH, Li Q, Zhang YF, Zhu L, Zhang YL, Yu Y, Xiao GG, Sun YW, Ji J, Zhang ZG., Free PMC Article | 07/31/2021 |
| Prolactin receptor expression as a novel prognostic biomarker for triple negative breast cancer patients. | Prolactin receptor expression as a novel prognostic biomarker for triple negative breast cancer patients.
Motamedi B, Rafiee-Pour HA, Khosravi MR, Kefayat A, Baradaran A, Amjadi E, Goli P. | 06/12/2021 |
| Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer. | Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer.
Menendez JA, Peirce SK, Papadimitropoulou A, Cuyàs E, Steen TV, Verdura S, Vellon L, Chen WY, Lupu R., Free PMC Article | 05/29/2021 |
| Changes in prolactin receptor location in prostate tumors.", trans "Cambios en la localizacion del receptor prolactina en tumores prostaticos. | Changes in prolactin receptor location in prostate tumors.
López Fontana G, Rey L, Santiano F, López Fontana R, López Laur JD, Zyla L, Valdemoros P, Guerrero-Giménez ME, Fernández-Muñoz JM, Gómez S, Bruna F, Guglielmi JM, Carón R, López Fontana C. | 05/8/2021 |
| Association between prolactin receptor expression and proliferation in the endometrium of obese women with polycystic ovary syndrome. | Association between prolactin receptor expression and proliferation in the endometrium of obese women with polycystic ovary syndrome.
Paulson M, Norstedt G, Sahlin L, Hirschberg AL. | 12/12/2020 |
| Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem Cell Differentiation into the NK Cell Lineage. | Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem Cell Differentiation into the NK Cell Lineage.
Tufa DM, Shank T, Yingst AM, Trahan GD, Shim S, Lake J, Woods R, Jones K, Verneris MR., Free PMC Article | 12/5/2020 |
| PRLR probably plays a different role in the development and progression of breast cancer. In luminal A and luminal B HER2-positive subtypes PRLR may act as an oncogen, and in luminal B HER2-negative and ER-, PR-negative subtypes can play a tumor suppressor role. | [Analysis of prolactin receptor expression in breast cancer subtypes].
Kalinina TS, Kononchuk VV, Sidorov SV, Gulyaeva LF. | 03/28/2020 |
| our results identify an association between a gain-of-function PRLR variant and prolactinomas and reveal a new etiology and potential therapeutic approach for these neoplasms. | Association of prolactin receptor (PRLR) variants with prolactinomas.
Gorvin CM, Newey PJ, Rogers A, Stokes V, Neville MJ, Lines KE, Ntali G, Lees P, Morrison PJ, Singhellakis PN, Malandrinou FC, Karavitaki N, Grossman AB, Karpe F, Thakker RV., Free PMC Article | 03/14/2020 |
| Prolactin-PRLR signaling may play a crucial role for the progression of type I endometrial cancer (EC) without involving the PTEN mutation in young hyperprolactinemic women without insulin resistance. | Serum Prolactin Contributes to Enhancing Prolactin Receptor and pJAK2 in Type I Endometrial Cancer Cells in Young Women Without Insulin Resistance.
Erdenebaatar C, Yamaguchi M, Monsur M, Saito F, Honda R, Tashiro H, Ohba T, Iyama KI, Katabuchi H. | 11/30/2019 |
| loss of the co-expression of PRLR, TGFbetaRI and TGFbetaRII is indicative of aggressiveness and poor patient survival outcomes in breast cancer. | Concomitant Expression of Prolactin Receptor and TGFβ Receptors in Breast Cancer: Association with Less Aggressive Phenotype and Favorable Patient Outcome.
Hachim IY, López-Ozuna VM, Hachim MY, Lebrun JJ, Ali S., Free PMC Article | 08/3/2019 |
| In a replication study of the association between the prolactin receptor gene intron C/T polymorphism (rs37389) and recurrent miscarriage, no association was found. | Prolactin receptor gene polymorphism and the risk of recurrent pregnancy loss: a case-control study.
Kim JJ, Choi YM, Lee SK, Yang KM, Paik EC, Jeong HJ, Jun JK, Han AR, Hwang KR, Hong MA. | 08/18/2018 |
| Low PRLR expression is associated with Triple Negative Breast Cancer. | Prolactin Pro-Differentiation Pathway in Triple Negative Breast Cancer: Impact on Prognosis and Potential Therapy.
López-Ozuna VM, Hachim IY, Hachim MY, Lebrun JJ, Ali S., Free PMC Article | 06/30/2018 |
| These results illustrate promising antitumor activity against PRLR-positive breast cancer xenografts and support the evaluation of anti-PRLR antibody-drug conjugate as potential therapeutic agents in breast cancer. | Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody-Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers.
Kelly MP, Hickey C, Makonnen S, Coetzee S, Jalal S, Wang Y, Delfino F, Shan J, Potocky TB, Chatterjee I, Andreev J, Kunz A, D'Souza C, Giurleo JT, Nittoli T, Trail PA, Thurston G, Kirshner JR. | 03/31/2018 |
| Prl receptor is expressed at different levels in the majority of glioblastoma multiforme tumors. Prolactin stimulation resulted in increased STAT5 phosphorylation and increased cellular invasion. | Stimulation of prolactin receptor induces STAT-5 phosphorylation and cellular invasion in glioblastoma multiforme.
Alkharusi A, Yu S, Landázuri N, Zadjali F, Davodi B, Nyström T, Gräslund T, Rahbar A, Norstedt G., Free PMC Article | 02/24/2018 |
| PRLRI146L and PRLRI176V variants are not associated with breast cancer or multiple breast fibroadenomas risk. | Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk.
Chakhtoura Z, Laki F, Bernadet M, Cherifi I, Chiche A, Pigat N, Bernichtein S, Courtillot C, Boutillon F, Bièche I, Vacher S, Tanguy ML, Bissery A, Grouthier V, Camparo P, Foretz M, Do Cruzeiro M, Pierre R, Rakotozafy F, Tichet J, Tejedor I, Guidotti JE, Sigal-Zafrani B, Goffin V, Touraine P. | 07/1/2017 |