Comparison of pancreatic enzyme abnormalities and protease-activated receptor-2-positive eosinophils in the duodenum of patients with functional dyspepsia-irritable bowel syndrome overlap with functional dyspepsia alone in Asian populations. | Comparison of pancreatic enzyme abnormalities and protease-activated receptor-2-positive eosinophils in the duodenum of patients with functional dyspepsia-irritable bowel syndrome overlap with functional dyspepsia alone in Asian populations. Futagami S, Kessoku T, Kasai Y, Higurashi T, Nakajima A, Agawa S, Yamawaki H, Nakamura K, Habiro M, Kawawa R, Ueki N, Higashida S, Watanabe Y, Yamato H, Yamamoto T, Takasaki Y, Ito K, Hojo M, Isayama H, Motoda N, Ohashi R, Siah KTH, Ng CK, Gwee KA. | 11/28/2023 |
PRG2 and AQPEP are misexpressed in fetal membranes in placenta previa and percretadagger. | PRG2 and AQPEP are misexpressed in fetal membranes in placenta previa and percreta†. Zhang ET, Hannibal RL, Badillo Rivera KM, Song JHT, McGowan K, Zhu X, Meinhardt G, Knöfler M, Pollheimer J, Urban AE, Folkins AK, Lyell DJ, Baker JC., Free PMC Article | 12/25/2021 |
Development and application of novel immunoassays for eosinophil granule major basic proteins to evaluate eosinophilia and myeloproliferative disorders. | Development and application of novel immunoassays for eosinophil granule major basic proteins to evaluate eosinophilia and myeloproliferative disorders. Squillace DL, Checkel JL, Tefferi A, Kita H, Gleich GJ., Free PMC Article | 10/2/2021 |
Mechanism of atopic cataract caused by eosinophil granule major basic protein. | Mechanism of atopic cataract caused by eosinophil granule major basic protein. Yamamoto N, Hiramatsu N, Isogai S, Kondo M, Imaizumi K, Horiguchi M. | 03/13/2021 |
Low PRG2 expression is associated with drug resistance in Chronic myeloid leukemia. | Re-Expression of Bone Marrow Proteoglycan-2 by 5-Azacytidine is associated with STAT3 Inactivation and Sensitivity Response to Imatinib in Resistant CML Cells. Al-Jamal HAN, Johan MF, Mat Jusoh SA, Ismail I, Wan Taib WR., Free PMC Article | 10/27/2018 |
MBP-1 aggregation is important for innate immunity and immunopathology mediated by eosinophils.MBP-1 toxicity is restrained via crystallization in eosinophil secretory granules. | Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Soragni A, Yousefi S, Stoeckle C, Soriaga AB, Sawaya MR, Kozlowski E, Schmid I, Radonjic-Hoesli S, Boutet S, Williams GJ, Messerschmidt M, Seibert MM, Cascio D, Zatsepin NA, Burghammer M, Riekel C, Colletier JP, Riek R, Eisenberg DS, Simon HU., Free PMC Article | 05/31/2018 |
free protein in nasal mucus can be used as a biomarker to diagnose chronic rhinosinusitis | An immunologic test for chronic rhinosinusitis based on free intranasal eosinophilic major basic protein. Ponikau JU, Winter LA, Kephart GM, Squillace DL, Hershcovitch MD, Moon S, Sherris DA, Kern EB, Gleich GJ, Kita H. | 10/24/2015 |
mRNA levels of eosinophil granule proteins, rather than sputum eosinophil%, may reflect airway hyperresponsiveness and airflow limitation. | Expression levels of eosinophil granule protein mRNAs in induced sputum reflect airway hyperresponsiveness and airflow limitation. Jung JW, Kang HR, Lee HS, Park HW, Cho SH, Min KU, Sohn SW. | 12/6/2014 |
This protein contains a peptide that displays strong antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. | Localization of somatostatin-like immunoreactivity in the pancreatic islets of the hagfish, Myxine glutinosa and the lamprey Lampetra fluviatilis. Van Noorden S, Ostberg Y, Pearse AG. | 11/25/2014 |
Eosinophil major basic protein activates human cord blood mast cells primed with fibroblast membranes by integrin-beta1. | Eosinophil major basic protein activates human cord blood mast cells primed with fibroblast membranes by integrin-β1. Ben-Zimra M, Bachelet I, Seaf M, Gleich GJ, Levi-Schaffer F. | 05/17/2014 |
During pregnancy, the proform of eosinophil major basic protein-angiotensinogen constitutes the major form in late pregnancy. | Formation of high-molecular-weight angiotensinogen during pregnancy is a result of competing redox reactions with the proform of eosinophil major basic protein. Kløverpris S, Skov LL, Glerup S, Pihl K, Christiansen M, Oxvig C. | 02/9/2013 |
Combinations of respiratory syncytial virus and MBP synergistically induced cell death in pulmonary alveolar epithelial cells (A549). | Effects of respiratory syncytial virus infection and major basic protein derived from eosinophils in pulmonary alveolar epithelial cells (A549). Ishioka T, Kimura H, Kita H, Obuchi M, Hoshino H, Noda M, Nishina A, Kozawa K, Kato M. | 07/30/2011 |
The expression of MBP in nasal mucus obtained from chronic rhinosinusitispatients was obviously higher than that of nasal mucus obtained from controls. | [Expression and its significance of eosinophil major basic protein in chronic rhinosinusitis]. Hou J, Zhou B, Zhang L, Li Y, Liu M, Wei Y, Huang Q, Wang Y. | 06/18/2011 |
MBP and NE collaborated to cause the pathological effects of nasal polyps. | [Expression of eosinophil major basic protein and neutrophil elastase in nasal polyp tissue and secretion]. Zhang C, Jiang Y, Chen J, Zheng L, Wang J, Shen H. | 06/18/2011 |
novel transcript was alternatively transcribed from intron III of the ENO1 gene and was feasible for MBP-1 production | MBP-1 is efficiently encoded by an alternative transcript of the ENO1 gene but post-translationally regulated by proteasome-dependent protein turnover. Lung J, Liu KJ, Chang JY, Leu SJ, Shih NY. | 11/6/2010 |
Observational study of gene-disease association. (HuGE Navigator) | New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. | 04/7/2010 |
The proMBP is a novel first trimester serum marker for adverse pregnancy outcome. | The proform of eosinophil major basic protein: a new maternal serum marker for adverse pregnancy outcome. Pihl K, Larsen T, Rasmussen S, Krebs L, Christiansen M. | 02/8/2010 |
addition to granule-stored MBP, even unstimulated eosinophils contained appreciable amounts of MBP within secretory vesicles | Vesicle-mediated secretion of human eosinophil granule-derived major basic protein. Melo RC, Spencer LA, Perez SA, Neves JS, Bafford SP, Morgan ES, Dvorak AM, Weller PF., Free PMC Article | 01/21/2010 |
The significantly elevated levels of proMBP in myelofibrosis patients implies that proMBP could be an important stromal cytokine in bone marrow fibrosis. | Clinical correlates of serum pro-major basic protein in a spectrum of eosinophilic disorders and myelofibrosis. Ho CL, Kito H, Squillace DL, Lasho TL, Tefferi A. | 01/21/2010 |
No variation in genes major basic protein for Atopic dermatitis pathogenesis in this German cohort | Variation in genes encoding eosinophil granule proteins in atopic dermatitis patients from Germany. Parwez Q, Stemmler S, Epplen JT, Hoffjan S., Free PMC Article | 01/21/2010 |
knockdown of endogenous MBP-1 is involved in cellular senescence of HFF through p53-p21 pathway. | Knockdown of MBP-1 in human foreskin fibroblasts induces p53-p21 dependent senescence. Ghosh AK, Kanda T, Steele R, Ray RB., Free PMC Article | 01/21/2010 |
Pregnancy-associated plasma protein A is involved in processes preceding vulnerable plaque development in acute coronary syndrome. | Pregnancy-associated plasma protein A and proform eosinophilic major basic protein in the detection of different types of coronary artery disease. Hájek P, Macek M, Hladíková M, Houbová B, Alan D, Durdil V, Fiedler J, Malý M, Ostádal P, Veselka J, Krebsová A. | 01/21/2010 |
two regions shown previously to contain the cytotoxic and cytostimulatory properties of MBP are accessible for ligand interaction in cell surface-bound MBP | The proform of the eosinophil major basic protein binds the cell surface through a site distinct from its C-type lectin ligand-binding region. Glerup S, Kløverpris S, Oxvig C. | 01/21/2010 |
the proform of eosinophil major basic protein inhibits the proteolytic activity of PAPP-A | Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements. Glerup S, Boldt HB, Overgaard MT, Sottrup-Jensen L, Giudice LC, Oxvig C. | 01/21/2010 |
Deposits of eosinophilic MBP are found on the surface of eosinophils and damaged muscle fibers surrounded by eosinophils in patients with idiopathic eosinophilic myositis. | Eosinophilic major basic protein and interleukin-5 in eosinophilic myositis. Murata K, Sugie K, Takamure M, Fujimoto T, Ueno S. | 01/21/2010 |