| De novo variants in GATAD2A in individuals with a neurodevelopmental disorder: GATAD2A-related neurodevelopmental disorder. | De novo variants in GATAD2A in individuals with a neurodevelopmental disorder: GATAD2A-related neurodevelopmental disorder.
Werren EA, Guxholli A, Jones N, Wagner M, Hannibal I, Granadillo JL, Tyndall AV, Moccia A, Kuehl R, Levandoski KM, Day-Salvatore DL, Wheeler M, University of Washington Center for Mendelian Genomics, Chong JX, Bamshad MJ, Innes AM, Pierson TM, Mackay JP, Bielas SL, Martin DM., Free PMC Article | 05/17/2023 |
| lncKRT16P6 promotes tongue squamous cell carcinoma progression by sponging miR3180 and regulating GATAD2A expression. | lncKRT16P6 promotes tongue squamous cell carcinoma progression by sponging miR‑3180 and regulating GATAD2A expression.
Zhang M, Wu L, Wang X, Chen J., Free PMC Article | 08/6/2022 |
| p66alpha Suppresses Breast Cancer Cell Growth and Migration by Acting as Co-Activator of p53. | p66α Suppresses Breast Cancer Cell Growth and Migration by Acting as Co-Activator of p53.
Zhang Q, Zhang Y, Zhang J, Zhang D, Li M, Yan H, Zhang H, Song L, Wang J, Hou Z, Yang Y, Zou X., Free PMC Article | 01/8/2022 |
| Germinal GLT8D1, GATAD2A and SLC25A39 mutations in a patient with a glomangiopericytal tumor and five different sarcomas over a 10-year period. | Germinal GLT8D1, GATAD2A and SLC25A39 mutations in a patient with a glomangiopericytal tumor and five different sarcomas over a 10-year period.
Beddok A, Pérot G, Le Guellec S, Thebault N, Coutte A, Sevestre H, Chauffert B, Chibon F., Free PMC Article | 10/23/2021 |
| GATA zinc finger domain-containing protein 2A (GATAD2A) deficiency reactivates fetal haemoglobin in patients with beta-thalassaemia through impaired formation of methyl-binding domain protein 2 (MBD2)-containing nucleosome remodelling and deacetylation (NuRD) complex. | GATA zinc finger domain-containing protein 2A (GATAD2A) deficiency reactivates fetal haemoglobin in patients with β-thalassaemia through impaired formation of methyl-binding domain protein 2 (MBD2)-containing nucleosome remodelling and deacetylation (NuRD) complex.
Liang Y, Zhang X, Liu Y, Wang L, Ye Y, Tan X, Pu J, Zhang Q, Bao X, Wei X, Li D, Kurita R, Nakamura Y, Li D, Xu X. | 10/2/2021 |
| A shared genetic contribution to breast cancer and schizophrenia. | A shared genetic contribution to breast cancer and schizophrenia.
Lu D, Song J, Lu Y, Fall K, Chen X, Fang F, Landén M, Hultman CM, Czene K, Sullivan P, Tamimi RM, Valdimarsdóttir UA., Free PMC Article | 10/3/2020 |
| This study unveils a novel biomarker panel consisting of the hsa_circ_0058124/NOTCH3/GATAD2A axis which is critical for papillary thyroid cancer (PTC) tumorigenesis and invasiveness and may represent a novel therapeutic target for intervening in PTC progression. | Hsa_circ_0058124 promotes papillary thyroid cancer tumorigenesis and invasiveness through the NOTCH3/GATAD2A axis.
Yao Y, Chen X, Yang H, Chen W, Qian Y, Yan Z, Liao T, Yao W, Wu W, Yu T, Chen Y, Zhang Y., Free PMC Article | 01/18/2020 |
| circ-GATAD2A promotes the replication of H1N1 by inhibiting autophagy. | Circular RNA GATAD2A promotes H1N1 replication through inhibiting autophagy.
Yu T, Ding Y, Zhang Y, Liu Y, Li Y, Lei J, Zhou J, Song S, Hu B. | 05/4/2019 |
| The MYND domain of ZMYND8 directly interacts with PPPLPhi motifs in the NuRD subunit GATAD2A. | ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage.
Spruijt CG, Luijsterburg MS, Menafra R, Lindeboom RG, Jansen PW, Edupuganti RR, Baltissen MP, Wiegant WW, Voelker-Albert MC, Matarese F, Mensinga A, Poser I, Vos HR, Stunnenberg HG, van Attikum H, Vermeulen M. | 11/26/2017 |
| Results showed that suppression of GATAD2A attenuated thyroid cancer cell proliferation and colony formation and promoted apoptosis suggesting it as an essential factor in thyroid cancer cell pathogenesis. | Knockdown of GATAD2A suppresses cell proliferation in thyroid cancer in vitro.
Wang Z, Kang J, Deng X, Guo B, Wu B, Fan Y. | 04/22/2017 |
| These factors lead to a binding affinity hierarchy of p66alpha for the different MBD2 homologues (MBD2 approximately MBD3 > MBD3L1 approximately MBD3L2). | Unique features of the anti-parallel, heterodimeric coiled-coil interaction between methyl-cytosine binding domain 2 (MBD2) homologues and GATA zinc finger domain containing 2A (GATAD2A/p66α).
Walavalkar NM, Gordon N, Williams DC Jr., Free PMC Article | 03/30/2013 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Human variation in alcohol response is influenced by variation in neuronal signaling genes.
Joslyn G, Ravindranathan A, Brush G, Schuckit M, White RL. | 04/7/2010 |