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    TRIM44 tripartite motif containing 44 [ Homo sapiens (human) ]

    Gene ID: 54765, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress.

    TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress.
    Wang Y, Lyu L, Vu T, McCarty N., Free PMC Article

    08/22/2024
    Overexpression of TRIM44 mediates the NF-kappaB pathway to promote the progression of ovarian cancer.

    Overexpression of TRIM44 mediates the NF-κB pathway to promote the progression of ovarian cancer.
    Yu Y, Li S, Sun J, Wang Y, Xie L, Guo Y, Li J, Han F.

    05/24/2024
    Silencing LINC00491 inhibits prostate cancer development through the miR-384/TRIM44 axis.

    Silencing LINC00491 inhibits prostate cancer development through the miR-384/TRIM44 axis.
    Zhou S, Wu C, Tang Q, Zhou X, He B, Chang P, He X.

    07/26/2023
    TRIM44 regulates tumor immunity in gastric cancer through LOXL2-dependent extracellular matrix remodeling.

    TRIM44 regulates tumor immunity in gastric cancer through LOXL2-dependent extracellular matrix remodeling.
    Zhang X, Wu X, Sun Y, Chu Y, Liu F, Chen C.

    04/14/2023
    Long noncoding RNA LINC00858 promotes the progression of ovarian cancer via regulating the miR-134-5p/TRIM44 axis.

    Long noncoding RNA LINC00858 promotes the progression of ovarian cancer via regulating the miR-134-5p/TRIM44 axis.
    Li P, Huang G.

    08/20/2022
    CircFBXW8 Acts an Oncogenic Role in the Malignant Progression of Non-small Cell Lung Carcinoma by miR-370-3p-Dependent Regulation of TRIM44.

    CircFBXW8 Acts an Oncogenic Role in the Malignant Progression of Non-small Cell Lung Carcinoma by miR-370-3p-Dependent Regulation of TRIM44.
    Wang X, Lv J, He B, Zhou D.

    07/16/2022
    Clinical Significance of TRIM44 Expression in Patients with Gastric Cancer.

    Clinical Significance of TRIM44 Expression in Patients with Gastric Cancer.
    Goshayeshi L, Afshar J, Mehrad-Majd H., Free PMC Article

    06/11/2022
    TRIM44 promotes BRCA1 functions in HR repair to induce Cisplatin Chemoresistance in Lung Adenocarcinoma by Deubiquitinating FLNA.

    TRIM44 promotes BRCA1 functions in HR repair to induce Cisplatin Chemoresistance in Lung Adenocarcinoma by Deubiquitinating FLNA.
    Zhang S, Cao M, Yan S, Liu Y, Fan W, Cui Y, Tian F, Gu R, Cui Y, Zhan Y, Sun Y, Xing Y, Cai L, Song Y., Free PMC Article

    05/14/2022
    YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44.

    YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44.
    Li W, Chen G, Feng Z, Zhu B, Zhou L, Zhang Y, Mai J, Jiang C, Zeng J., Free PMC Article

    03/19/2022
    Knockdown of circRAD23B Exerts Antitumor Response in Colorectal Cancer via the Regulation of miR-1205/TRIM44 axis.

    Knockdown of circRAD23B Exerts Antitumor Response in Colorectal Cancer via the Regulation of miR-1205/TRIM44 axis.
    Han B, Wang X, Yin X.

    03/12/2022
    TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression.

    TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression.
    Lyu L, Lin TC, McCarty N., Free PMC Article

    01/8/2022
    MiR-34a-5p directly targeting TRIM44 affects the biological behavior of ovarian cancer cells.

    MiR-34a-5p directly targeting TRIM44 affects the biological behavior of ovarian cancer cells.
    Li HL, Duan YA, Zhao N.

    09/18/2021
    TRIM44 facilitates ovarian cancer proliferation, migration, and invasion by inhibiting FRK.

    TRIM44 facilitates ovarian cancer proliferation, migration, and invasion by inhibiting FRK.
    Yu XZ, Yuan JL, Ye H, Yi K, Qie MR, Hou MM.

    08/14/2021
    The Novel Target of Colorectal Carcinoma: TRIM44 Regulates Cell Migration and Invasion via Activation of CXCR4/NF-kappaB Signaling.

    The Novel Target of Colorectal Carcinoma: TRIM44 Regulates Cell Migration and Invasion via Activation of CXCR4/NF-κB Signaling.
    Kou T, Sha D, Wang F, He T, He X.

    07/31/2021
    Down-regulation of long non-coding RNA DUXAP8 suppresses proliferation, metastasis and EMT by modulating miR-498 through TRIM44-mediated AKT/mTOR pathway in non-small-cell lung cancer.

    Down-regulation of long non-coding RNA DUXAP8 suppresses proliferation, metastasis and EMT by modulating miR-498 through TRIM44-mediated AKT/mTOR pathway in non-small-cell lung cancer.
    Ji X, Tao R, Sun LY, Xu XL, Ling W.

    03/20/2021
    Knockdown of HIF1A-AS2 suppresses TRIM44 to protect cardiomyocytes against hypoxia-induced injury.

    Knockdown of HIF1A-AS2 suppresses TRIM44 to protect cardiomyocytes against hypoxia-induced injury.
    Luo F, Wu Y, Zhu L, Zhang J, Liu Y, Jia W.

    02/6/2021
    Expression of tripartite motif-containing 44 and its prognostic and clinicopathological value in human malignancies:a meta-analysis.

    Expression of tripartite motif-containing 44 and its prognostic and clinicopathological value in human malignancies:a meta-analysis.
    Xiao G, Yang Q, Bao Z, Mao H, Zhang Y, Lin S., Free PMC Article

    01/23/2021
    ELFN1-AS1 accelerates the proliferation and migration of colorectal cancer via regulation of miR-4644/TRIM44 axis.

    ELFN1-AS1 accelerates the proliferation and migration of colorectal cancer via regulation of miR-4644/TRIM44 axis.
    Lei R, Feng L, Hong D.

    12/5/2020
    miR-192-5p suppresses the progression of lung cancer bone metastasis by targeting TRIM44.

    miR-192-5p suppresses the progression of lung cancer bone metastasis by targeting TRIM44.
    Zou P, Zhu M, Lian C, Wang J, Chen Z, Zhang X, Yang Y, Chen X, Cui X, Liu J, Wang H, Wen Q, Yi J., Free PMC Article

    11/21/2020
    TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway. TRIM44 was associated with oncogenic potential of glioma. Targeting TRIM44 might be beneficial for glioma therapy.

    TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway.
    Zhou X, Yang Y, Ma P, Wang N, Yang D, Tu Q, Sun B, Xiang T, Zhao X, Hou Z, Fang X.

    04/11/2020
    TRIM44 promotes cell proliferation by regulating FRK.

    TRIM44 promotes cell proliferation and migration by inhibiting FRK in renal cell carcinoma.
    Yamada Y, Kimura N, Takayama KI, Sato Y, Suzuki T, Azuma K, Fujimura T, Ikeda K, Kume H, Inoue S., Free PMC Article

    03/14/2020
    Studies indicate that tripartite motif containing 44 (TRIM44)expression contributes to the progression of cervical cancer, and could be used as a marker of clinical diagnosis and prognosis of patients with cervical cancer.

    High TRIM44 expression as a valuable biomarker for diagnosis and prognosis in cervical cancer.
    Liu S, Meng F, Ding J, Ji H, Lin M, Zhu J, Ma R., Free PMC Article

    02/29/2020
    Study demonstrates that TRIM44 is significantly amplified in melanoma tissues, and overexpression of TRIM44 is associated with a malignant phenotype of melanoma. TRIM44 is the target of miR-26b-5p, which is significantly downregulated in melanoma tissues and may be responsible for the overexpression of TRIM44.

    TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4.
    Wei CY, Wang L, Zhu MX, Deng XY, Wang DH, Zhang SM, Ying JH, Yuan X, Wang Q, Xuan TF, He AQ, Qi FZ, Gu JY., Free PMC Article

    08/17/2019
    Results suggest elevated TRIM44 promotes ICC development by inducing cell EMT and apoptosis resistance.

    Elevated TRIM44 promotes intrahepatic cholangiocarcinoma progression by inducing cell EMT via MAPK signaling.
    Peng R, Zhang PF, Zhang C, Huang XY, Ding YB, Deng B, Bai DS, Xu YP., Free PMC Article

    07/6/2019
    High TRIM44 expression is associated with multiple myeloma.

    TRIM44 promotes quiescent multiple myeloma cell occupancy and survival in the osteoblastic niche via HIF-1α stabilization.
    Chen Z, Lin TC, Bi X, Lu G, Dawson BC, Miranda R, Medeiros LJ, McNiece I, McCarty N., Free PMC Article

    05/25/2019
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