| Comprehensive analysis to identify PUS7 as a prognostic biomarker from pan-cancer analysis to osteosarcoma validation. | Comprehensive analysis to identify PUS7 as a prognostic biomarker from pan-cancer analysis to osteosarcoma validation.
Dong B, Wang B, Fan M, Zhang J, Zhao Z., Free PMC Article | 10/11/2024 |
| PUS7-dependent pseudouridylation of ALKBH3 mRNA inhibits gastric cancer progression. | PUS7-dependent pseudouridylation of ALKBH3 mRNA inhibits gastric cancer progression.
Chang Y, Jin H, Cui Y, Yang F, Chen K, Kuang W, Huo C, Xu Z, Li Y, Lin A, Yang B, Liu W, Xie S, Zhou T., Free PMC Article | 10/3/2024 |
| PUS7 promotes the proliferation of colorectal cancer cells by directly stabilizing SIRT1 to activate the Wnt/beta-catenin pathway. | PUS7 promotes the proliferation of colorectal cancer cells by directly stabilizing SIRT1 to activate the Wnt/β-catenin pathway.
Zhang Q, Fei S, Zhao Y, Liu S, Wu X, Lu L, Chen W. | 01/28/2023 |
| PUS7 deficiency in human patients causes profound neurodevelopmental phenotype by dysregulating protein translation. | PUS7 deficiency in human patients causes profound neurodevelopmental phenotype by dysregulating protein translation.
Han ST, Kim AC, Garcia K, Schimmenti LA, Macnamara E, Network UD, Gahl WA, Malicdan MC, Tifft CJ., Free PMC Article | 04/30/2022 |
| Pseudouridylate Synthase 7 Promotes Cell Proliferation and Invasion in Colon Cancer Through Activating PI3K/AKT/mTOR Signaling Pathway. | Pseudouridylate Synthase 7 Promotes Cell Proliferation and Invasion in Colon Cancer Through Activating PI3K/AKT/mTOR Signaling Pathway.
Du J, Gong A, Zhao X, Wang G. | 04/23/2022 |
| Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing. | Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing.
Martinez NM, Su A, Burns MC, Nussbacher JK, Schaening C, Sathe S, Yeo GW, Gilbert WV., Free PMC Article | 03/5/2022 |
| The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface. | The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface.
Guegueniat J, Halabelian L, Zeng H, Dong A, Li Y, Wu H, Arrowsmith CH, Kothe U., Free PMC Article | 01/1/2022 |
| HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance. | HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.
Song D, Guo M, Xu S, Song X, Bai B, Li Z, Chen J, An Y, Nie Y, Wu K, Wang S, Zhao Q., Free PMC Article | 12/25/2021 |
| Pseudouridine synthase 7 is a nuclear protein involved in stem cell development and intellectual disabilities, and is a novel interactor of SIRT1. The binding regions are predicted and analyzed based on molecular docking studies. The direct interaction occurs between SIRT1 and PUS7, as evidenced by pull-down studies and surface plasmon resonance (SPR) assay. | Biochemical insight into pseudouridine synthase 7 (PUS7) as a novel interactor of sirtuin, SIRT1.
Dalal S, Deshmukh P, Unni S, Padavattan S, Padmanabhan B. | 06/13/2020 |
| Our results confirm that PUS7 is a bona fide Mendelian disease gene and expand the list of human diseases caused by impaired pseudouridylation. | PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly.
Shaheen R, Tasak M, Maddirevula S, Abdel-Salam GMH, Sayed ISM, Alazami AM, Al-Sheddi T, Alobeid E, Phizicky EM, Alkuraya FS., Free PMC Article | 03/30/2019 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |