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    KRT20 keratin 20 [ Homo sapiens (human) ]

    Gene ID: 54474, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Expression of cytokeratin 7/20 and Ki67 in Helicobacter pylori-associated gastritis and intestinal metaplasia.

    Expression of cytokeratin 7/20 and Ki67 in Helicobacter pylori-associated gastritis and intestinal metaplasia.
    Ismael AT, Abdulhameed RA, Jalal JA, Tawfeeq RD, Ommar A, Jalal A.

    09/9/2024
    Relevance of CD20 antigen expression among paediatric patients with B-lineage acute lymphoblastic leukaemia.

    Relevance of CD20 antigen expression among paediatric patients with B-lineage acute lymphoblastic leukaemia.
    Bommannan K, Arumugam JR, Radhakrishnan V, Sundersingh S.

    04/16/2024
    Loss of CD20 expression as a mechanism of resistance to mosunetuzumab in relapsed/refractory B-cell lymphomas.

    Loss of CD20 expression as a mechanism of resistance to mosunetuzumab in relapsed/refractory B-cell lymphomas.
    Schuster SJ, Huw LY, Bolen CR, Maximov V, Polson AG, Hatzi K, Lasater EA, Assouline SE, Bartlett NL, Budde LE, Matasar MJ, Koeppen H, Piccione EC, Wilson D, Wei MC, Yin S, Penuel E., Free PMC Article

    03/1/2024
    The Association of P53, CK29, and FGFR3 Overexpression with the Characteristics of Urothelial Cell Carcinoma of the Bladder.

    P53, CK20, and FGFR3 Overexpression is Associated with the Characteristics of Urothelial Cell Carcinoma of the Bladder.
    Asgari M, Firouzi F, Abolhasani M, Bahadoram M, Barahman M, Madjd Z, Mehrazam M, Hassanzadeh S, Akade E., Free PMC Article

    10/5/2023
    Significance of Intraperitoneal-free KRT20 and CEACAM6 mRNA Expression for Peritoneal Recurrence of Gastric Cancer.

    Significance of Intraperitoneal-free KRT20 and CEACAM6 mRNA Expression for Peritoneal Recurrence of Gastric Cancer.
    Kaku H, Aoyagi K, Sudo T, Tanaka Y, Minami T, Isobe T, Kizaki J, Umetani Y, Murakami N, Fujita F, Akagi Y.

    08/6/2022
    Identifying KRT20 as a Potential Key Gene in Lymphatic Metastasis of Head and Neck Squamous Cell Carcinoma.

    Identifying KRT20 as a Potential Key Gene in Lymphatic Metastasis of Head and Neck Squamous Cell Carcinoma.
    Zhang YF, Huang Q, Huang HY, Ren HL, Zhou L., Free PMC Article

    07/16/2022
    Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers.

    Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers.
    Dum D, Menz A, Völkel C, De Wispelaere N, Hinsch A, Gorbokon N, Lennartz M, Luebke AM, Hube-Magg C, Kluth M, Fraune C, Möller K, Bernreuther C, Lebok P, Clauditz TS, Jacobsen F, Sauter G, Uhlig R, Wilczak W, Steurer S, Minner S, Marx AH, Simon R, Burandt E, Krech T.

    06/11/2022
    Supervised machine learning algorithm identified KRT20, BATF and TP63 as biologically relevant biomarkers for bladder biopsy specimens from interstitial cystitis/bladder pain syndrome patients.

    Supervised machine learning algorithm identified KRT20, BATF and TP63 as biologically relevant biomarkers for bladder biopsy specimens from interstitial cystitis/bladder pain syndrome patients.
    Kamasako T, Kaga K, Inoue KI, Hariyama M, Yamanishi T.

    05/7/2022
    Biomarkers CDX2, CK20, CK7 in Schoolchildren with Gastritis in the Realization of Familial Predisposition of Stomach Cancer.

    Biomarkers CDX2, CK20, CK7 in Schoolchildren with Gastritis in the Realization of Familial Predisposition of Stomach Cancer.
    Polivanova TV, Kasparov EV, Vshivkov VA, Peretyatko OV.

    04/2/2022
    Differential expression of CK7, CK20, CDX2 in intestinal and pancreatobiliary types of preriampullary carcinoma.

    Differential expression of CK7, CK20, CDX2 in intestinal and pancreatobiliary types of preriampullary carcinoma.
    Sree UD, Prayaga AK, R Reddy VV, Rukmanghadha N, Chowhan AK, Phaneendra BV.

    02/26/2022
    The clinical significance of cytokeratin 20 staining pattern in Merkel cell carcinoma.

    The clinical significance of cytokeratin 20 staining pattern in Merkel cell carcinoma.
    Sakata Y, Inaba Y, Kunimoto K, Kaminaka C, Yamamoto Y, Iwahashi Y, Murata SI, Asamura S, Jinnin M.

    12/11/2021
    Urothelial Carcinoma In Situ of the Bladder: Correlation of CK20 Expression With Adaptive Immune Resistance, Response to BCG Therapy, and Clinical Outcome.

    Urothelial Carcinoma In Situ of the Bladder: Correlation of CK20 Expression With Adaptive Immune Resistance, Response to BCG Therapy, and Clinical Outcome.
    Lombardo KA, Murati Amador B, Parimi V, Hoffman-Censits J, Choi W, Hahn NM, Kates M, Bivalacqua TJ, McConkey D, Hoque MO, Matoso A., Free PMC Article

    10/30/2021
    Non-Muscle-Invasive Bladder Carcinoma with Respect to Basal Versus Luminal Keratin Expression.

    Non-Muscle-Invasive Bladder Carcinoma with Respect to Basal Versus Luminal Keratin Expression.
    Jung M, Jang I, Kim K, Moon KC., Free PMC Article

    02/27/2021
    Expression pattern of placenta specific 8 and keratin 20 in different types of gastrointestinal cancer.

    Expression pattern of placenta specific 8 and keratin 20 in different types of gastrointestinal cancer.
    Hung CS, Wang YC, Guo JW, Yang RN, Lee CL, Shen MH, Huang CC, Huang CJ, Yang JY, Liu CY., Free PMC Article

    10/10/2020
    The large-section CK20 staining technique is useful for the detection of infiltration on the distal wall and mesangial metastasis in patients with middle and lower rectal cancer.

    Usefulness of large-section cytokeratin 20 in the detection of intestinal wall infiltration and mesangial metastasis in patients with middle and lower rectal cancer.
    Shan KS, Zhang XP, Wang JS, Guo XB, Shang L, Tian F, Jing CQ, Li LP, Wan DS, Li CS.

    08/3/2019
    Increased cytokeratin 20 messenger RNA expression is associated with Micrometastasis and recurrence in Gastric Carcinoma.

    Aberrant Cytokeratin 20 mRNA Expression in Peripheral Blood and Lymph Nodes Indicates Micrometastasis and Poor Prognosis in Patients With Gastric Carcinoma.
    You X, Wang Y, Wu J, Liu Q, Chen D, Tang D, Wang D., Free PMC Article

    05/18/2019
    combination of KRT5 and KRT20 allowed identification of patients with a very poor prognosis (KRT20/KRT5(-), 5-year DSS 0%, p < 0.0001). In silico analysis of the independent MDACC cohorts revealed congruent results (5-year DSS for KRT20 low vs. high: 84% vs. 40%, p = 0.042).

    mRNA-Expression of KRT5 and KRT20 Defines Distinct Prognostic Subgroups of Muscle-Invasive Urothelial Bladder Cancer Correlating with Histological Variants.
    Eckstein M, Wirtz RM, Gross-Weege M, Breyer J, Otto W, Stoehr R, Sikic D, Keck B, Eidt S, Burger M, Bolenz C, Nitschke K, Porubsky S, Hartmann A, Erben P., Free PMC Article

    02/2/2019
    Carcinoid-like/labyrinthine pattern of cell arrangement in vimentin/cytokeratin 20 expressing sebaceous neoplasms may represent a morphological phenotype of sebaceous mantles.

    Carcinoid-Like/Labyrinthine Pattern in Sebaceous Neoplasms Represents a Sebaceous Mantle Phenotype: Immunohistochemical Analysis of Aberrant Vimentin Expression and Cytokeratin 20-Positive Merkel Cell Distribution.
    Goto K, Anan T, Fukumoto T, Kimura T, Misago N.

    06/23/2018
    In our cohort of specimens with equivocal urothelial atypia, very few patients without a prior diagnosis of bladder cancer progressed to diagnostic cancer (1 of 22), suggesting that CK20 and p53 staining results should be interpreted with caution in de novo atypia.

    CK20 and p53 Immunohistochemical Staining Patterns in Urinary Bladder Specimens With Equivocal Atypia.
    Arias-Stella JA 3rd, Shah AB, Gupta NS, Williamson SR.

    01/6/2018
    results demonstrate the diagnostic value of urinary cytology and confirm CK 20 as an adjunct marker for the diagnosis of urothelial carcinoma.

    The diagnostic value of cytohistological urine analysis and cytokeratin 20 in malignant and atypical urothelial cells.
    Negri S, Biavati P, Bondi A.

    11/26/2017
    findings of our study imply that sequential staining of CK20 and E-cadherin prevents false-positive classification of BCC. Furthermore, our study demonstrated that p40 exhibits the same staining pattern in BCC, TE, and TB

    p40 in Conjunction With CK20 and E-Cadherin Distinguishes Primary Adnexal Neoplasms of the Skin.
    Andruszkow JH, Oll M, Förster S, Knüchel R, Jäkel J.

    06/3/2017
    In stomach adenocarcinomas, CDH17 positively stained 64.0% (112 of 175) of tissues, compared to CK20 and CDX2, where staining was observed in only 24.6% (43 of 175) and 46.9% (82 of 175), respectively.

    CDH17 Is a More Sensitive Marker for Gastric Adenocarcinoma Than CK20 and CDX2.
    Altree-Tacha D, Tyrrell J, Haas T.

    03/11/2017
    results demonstrated upregulation of fibroblast growth factor receptor 1 and CK20 expressions in cancer bladder tissues

    Fibroblast growth factor receptor 1 and cytokeratin 20 expressions and their relation to prognostic variables in bladder cancer.
    Abdul-Maksoud RS, Shalaby SM, Elsayed WS, Elkady S.

    01/28/2017
    K20 expression was detected in 6 of 75 patients with triple-negative carcinoma

    Aberrant keratin 7 and 20 expression in triple-negative carcinoma of the breast.
    Kuroda H, Imai Y, Yamagishi H, Ueda Y, Kuroso K, Oishi Y, Ohashi H, Yamashita A, Yashiro Y, Fukushima H.

    10/22/2016
    Circulating tumor cell CK20 and survivin expression may effectively predict overall survival in metastic colorectal cancer patients receiving chemotherapy.

    Cytokeratin-20 and Survivin-Expressing Circulating Tumor Cells Predict Survival in Metastatic Colorectal Cancer Patients by a Combined Immunomagnetic qRT-PCR Approach.
    Ning Y, Hanna DL, Zhang W, Mendez A, Yang D, El-Khoueiry R, Matsusaka S, Sunakawa Y, Stremitzer S, Parekh A, Okazaki S, Berger MD, Barzi A, Lenz HJ., Free PMC Article

    08/6/2016
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