Clinical pathological significance and biological function of PLIN1 in hepatocellular carcinoma: bioinformatics analysis and in vitro experiments. | Clinical pathological significance and biological function of PLIN1 in hepatocellular carcinoma: bioinformatics analysis and in vitro experiments. Huang JH, Wei Y, Fang Z, Yu C, Zhang R, Feng ZB, Zeng LP., Free PMC Article | 09/4/2024 |
Correlational analysis of PLIN1 with inflammation in diabetic foot ulcer wounds. | Correlational analysis of PLIN1 with inflammation in diabetic foot ulcer wounds. Wang M, Cao X, Shang Y, Jiang Y, Chen P, Duan C, Zhang D, Wang P, Ji J, Gong Z. | 03/26/2024 |
Perilipin 1: a systematic review on its functions on lipid metabolism and atherosclerosis in mice and humans. | Perilipin 1: a systematic review on its functions on lipid metabolism and atherosclerosis in mice and humans. Desgrouas C, Thalheim T, Cerino M, Badens C, Bonello-Palot N. | 03/18/2024 |
Effect of an acute long-duration exercise bout on skeletal muscle lipid droplet morphology, GLUT 4 protein, and perilipin protein expression. | Effect of an acute long-duration exercise bout on skeletal muscle lipid droplet morphology, GLUT 4 protein, and perilipin protein expression. Bajpeyi S, Apaflo JN, Rosas V, Sepulveda-Rivera K, Varela-Ramirez A, Covington JD, Galgani JE, Ravussin E. | 11/15/2023 |
RS2289487 variation in PERILIPIN gene is a predictor of weight loss and protection against impaired glucose metabolism after a meal-replacement diet in postmenopausal obese females. | RS2289487 variation in PERILIPIN gene is a predictor of weight loss and protection against impaired glucose metabolism after a meal-replacement diet in postmenopausal obese females. de Luis D, Izaola O, Primo D, Aller R. | 11/3/2023 |
Lipid Droplet Protein PLIN1 Regulates Inflammatory Polarity in Human Macrophages and is Involved in Atherosclerotic Plaque Development by Promoting Stable Lipid Storage. | Lipid Droplet Protein PLIN1 Regulates Inflammatory Polarity in Human Macrophages and is Involved in Atherosclerotic Plaque Development by Promoting Stable Lipid Storage. Cho KY, Miyoshi H, Nakamura A, Greenberg AS, Atsumi T., Free PMC Article | 02/11/2023 |
Impact of blood perilipin A levels on obesity and metabolic health. | Impact of blood perilipin A levels on obesity and metabolic health. Ofori EK, Letsu BS, Amponsah SK, Ahenkorah J, Crabbe S, Kwao-Zigah G, Oppong SY, Diaba-Nuhoho P, Amanquah SD., Free PMC Article | 01/11/2023 |
Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy. | Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy. Mandel-Brehm C, Vazquez SE, Liverman C, Cheng M, Quandt Z, Kung AF, Parent A, Miao B, Disse E, Cugnet-Anceau C, Dalle S, Orlova E, Frolova E, Alba D, Michels A, Oftedal BE, Lionakis MS, Husebye ES, Agarwal AK, Li X, Zhu C, Li Q, Oral E, Brown R, Anderson MS, Garg A, DeRisi JL., Free PMC Article | 12/31/2022 |
Polymorphism PLIN1 11482 G>A interacts with dietary intake to modulate anthropometric measures and lipid profile in adults with normal-weight obesity syndrome. | Polymorphism PLIN1 11482 G>A interacts with dietary intake to modulate anthropometric measures and lipid profile in adults with normal-weight obesity syndrome. Holzbach LC, Silveira AGZ, Franco LP, Horst MA, Cominetti C. | 12/24/2022 |
Sex-Dependent Mediation of Leptin in the Association of Perilipin Polymorphisms with BMI and Plasma Lipid Levels in Children. | Sex-Dependent Mediation of Leptin in the Association of Perilipin Polymorphisms with BMI and Plasma Lipid Levels in Children. Vales-Villamarín C, Lumpuy-Castillo J, Gavela-Pérez T, de Dios O, Pérez-Nadador I, Soriano-Guillén L, Garcés C., Free PMC Article | 08/6/2022 |
Genetic Association between Different Metabolic Variants in APOA5 and PLIN1 in Type 2 Diabetes Mellitus among the Western Saudi Population: Case-Control Study. | Genetic Association between Different Metabolic Variants in APOA5 and PLIN1 in Type 2 Diabetes Mellitus among the Western Saudi Population: Case-Control Study. Bakhashab S, Alsulami T, Gusti AMT, Harakeh S, Al-Raddadi R, Alwazani WA, Alshaibi HF., Free PMC Article | 08/6/2022 |
PLIN1 Haploinsufficiency Causes a Favorable Metabolic Profile. | PLIN1 Haploinsufficiency Causes a Favorable Metabolic Profile. Patel KA, Burman S, Laver TW, Hattersley AT, Frayling TM, Weedon MN., Free PMC Article | 05/21/2022 |
Aquaglyceroporins and orthodox aquaporins in human adipocytes. | Aquaglyceroporins and orthodox aquaporins in human adipocytes. Huang P, Hansen JS, Saba KH, Bergman A, Negoita F, Gourdon P, Hagström-Andersson A, Lindkvist-Petersson K. | 01/1/2022 |
The Utility of Perilipin in Liposarcomas: PLIN1 Differentiates Round Cell Liposarcoma From Other Round Cell Sarcomas. | The Utility of Perilipin in Liposarcomas: PLIN1 Differentiates Round Cell Liposarcoma From Other Round Cell Sarcomas. Compton ML, Al-Rohil RN. | 10/30/2021 |
Perilipin 1 and adipophilin immunoexpression suggests the presence of lipid droplets in tooth germ, ameloblastoma, and ameloblastic carcinoma. | Perilipin 1 and adipophilin immunoexpression suggests the presence of lipid droplets in tooth germ, ameloblastoma, and ameloblastic carcinoma. Sánchez-Romero C, Carreón-Burciaga R, Gónzalez-Gónzalez R, Villarroel-Dorrego M, Molina-Frechero N, Bologna-Molina R. | 09/4/2021 |
High prevalence of mutations in perilipin 1 in patients with precocious acute coronary syndrome. | High prevalence of mutations in perilipin 1 in patients with precocious acute coronary syndrome. Bonello-Palot N, Laine M, Cuisset T, Ronchard T, Desgrouas C, Merono F, Ibrahim-Kosta M, Cerino M, Blanchard A, Bourgeois P, Levy N, Loundou A, Morange PE, Alessi MC, Badens C, Bonello L. | 12/19/2020 |
Identification of two heterozygous PLIN1 frameshift variants segregating with the phenotype in nine patients from four unrelated families. The Familial partial lipodystrophy 4 stereotypical signs included postpubertal partial lipoatrophy of variable severity, muscular hypertrophy, acromegaloid features, polycystic ovary syndrome and/or hirsutism, metabolic complications. | Diagnostic Challenge in PLIN1-Associated Familial Partial Lipodystrophy. Jéru I, Vantyghem MC, Bismuth E, Cervera P, Barraud S, PLIN1-Study Group, Auclair M, Vatier C, Lascols O, Savage DB, Vigouroux C., Free PMC Article | 05/30/2020 |
perilipin 1 is a promising marker for the differential diagnosis of liposarcomas from other soft tissue sarcomas, whereas perilipin 2 correlates negatively with tumor grade and may be therapeutically useful. | Perilipin 1 Expression Differentiates Liposarcoma from Other Types of Soft Tissue Sarcoma. Straub BK, Witzel HR, Pawella LM, Renner M, Eiteneuer E, Hashani M, Schirmacher P, Roth W, Mechtersheimer G. | 03/14/2020 |
Studied physiology of weight loss through gene expression of uncoupling protein 3(UCP3), perilipin 1 (PLIN1), and peroxisome proliferator activated receptor gamma (PPARG2) in obese female patients after low calorie diet intervention. With hypocaloric diet, found UCP3 reduced in obese patients and UCP3, PLIN1 and PPARG2 correlate positively with carbohydrate oxidation and negatively with lipid oxidation. | Influence of expression of UCP3, PLIN1 and PPARG2 on the oxidation of substrates after hypocaloric dietary intervention. Cortes de Oliveira C, Nicoletti CF, Pinhel MAS, de Oliveira BAP, Quinhoneiro DCG, Noronha NY, Fassini PG, Marchini JS, da Silva Júnior WA, Salgado Júnior W, Nonino CB. | 11/23/2019 |
Data indicate that perilipin 1 (PLIN1) specifically binds to cholesteryl esters, and that their dynamic properties direct segregation of perilipin 1 into topologically distinct micro domains on the lipid droplet. | Visualization of lipid directed dynamics of perilipin 1 in human primary adipocytes. Hansen JS, de Maré S, Jones HA, Göransson O, Lindkvist-Petersson K., Free PMC Article | 07/13/2019 |
These findings suggest that dual amphipathic helical regions mediate lipid droplets (LD) targeting and underpin the hierarchical binding of Plin1-3 to LDs. | Dual binding motifs underpin the hierarchical association of perilipins1-3 with lipid droplets. Ajjaji D, Ben M'barek K, Mimmack ML, England C, Herscovitz H, Dong L, Kay RG, Patel S, Saudek V, Small DM, Savage DB, Thiam AR., Free PMC Article | 06/29/2019 |
The study suggests that heterozygous variants that are predicted to result in PLIN1 haploinsufficiency are not a cause of familial partial lipodystrophy. | PLIN1 Haploinsufficiency Is Not Associated With Lipodystrophy. Laver TW, Patel KA, Colclough K, Curran J, Dale J, Davis N, Savage DB, Flanagan SE, Ellard S, Hattersley AT, Weedon MN., Free PMC Article | 06/1/2019 |
In pediatric controls, PLIN1 immunostaining was absent. PLIN1 was present in 1 child with HepC, mildly expressed in NAFL, and increased in NASH. In adults, PLIN1 immunostaining was detected in only 1 control adult and was significantly higher in adult NASH compared with NAFL. | Perilipin Staining Distinguishes Between Steatosis and Nonalcoholic Steatohepatitis in Adults and Children. Carr RM, Dhir R, Mahadev K, Comerford M, Chalasani NP, Ahima RS., Free PMC Article | 05/11/2019 |
PLIN1 gene is epigenetically regulated and promoter methylation is inversely correlated with basal lipolysis in obese women. | Epigenetic Regulation of PLIN 1 in Obese Women and its Relation to Lipolysis. Bialesova L, Kulyté A, Petrus P, Sinha I, Laurencikiene J, Zhao C, Wright KD, Arner P, Dahlman I., Free PMC Article | 05/4/2019 |
OPA1 mediates adrenergic control of lipolysis in human adipocytes by regulating phosphorylation of perilipin 1. | OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells. Rogne M, Chu DT, Küntziger TM, Mylonakou MN, Collas P, Tasken K., Free PMC Article | 03/9/2019 |