| Melanoma differentiation associated gene-9/syndecan binding protein promotes hepatocellular carcinoma. | Melanoma differentiation associated gene-9/syndecan binding protein promotes hepatocellular carcinoma.
Manna D, Reghupaty SC, Camarena MDC, Mendoza RG, Subler MA, Koblinski JE, Martin R, Dozmorov MG, Mukhopadhyay ND, Liu J, Qu X, Das SK, Lai Z, Windle JJ, Fisher PB, Sarkar D., Free PMC Article | 01/26/2024 |
| Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. | Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis.
Meyer A, Zack SR, Nijim W, Burgos A, Patel V, Zanotti B, Volin MV, Amin MA, Lewis MJ, Pitzalis C, Arami S, Karam JA, Sweiss NJ, Shahrara S., Free PMC Article | 01/5/2024 |
| Downregulation of stromal syntenin sustains AML development. | Downregulation of stromal syntenin sustains AML development.
Leblanc R, Ghossoub R, Goubard A, Castellano R, Fares J, Camoin L, Audebert S, Balzano M, Bou-Tayeh B, Fauriat C, Vey N, Garciaz S, Borg JP, Collette Y, Aurrand-Lions M, David G, Zimmermann P., Free PMC Article | 11/14/2023 |
| SDCBP promotes pancreatic cancer progression by preventing YAP1 from beta-TrCP-mediated proteasomal degradation. | SDCBP promotes pancreatic cancer progression by preventing YAP1 from β-TrCP-mediated proteasomal degradation.
Liu J, Bai W, Zhou T, Xie Y, Yang B, Sun J, Wang Y, Li X, Hou X, Liu Z, Fu D, Yan J, Jiang W, Zhao K, Zhou B, Yuan S, Guo Y, Wang H, Chang A, Gao S, Shi L, Huang C, Yang S, Hao J. | 08/10/2023 |
| PDZ interaction of the GABA transporter GAT1 with the syntenin-1 in Neuro-2a cells. | PDZ interaction of the GABA transporter GAT1 with the syntenin-1 in Neuro-2a cells.
Jahodova I, Baliova M, Jursky F. | 04/19/2023 |
| Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker. | Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker.
Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R., Free PMC Article | 08/28/2021 |
| Binding of syntenin-1 requires phosphorylation of UNC93B1 and provides a mechanism for dynamic regulation of TLR7 activation and signalling | UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity.
Majer O, Liu B, Kreuk LSM, Krogan N, Barton GM., Free PMC Article | 04/11/2020 |
| High Sdcbp expression is associated with B16 melanoma invasion. | MicroRNA-23a inhibits melanoma cell proliferation, migration, and invasion in mice through a negative feedback regulation of sdcbp and the MAPK/ERK signaling pathway.
Lu S, Xu Q. | 03/7/2020 |
| Our results suggest that syntenin-1 plays an important role in extinction of cued fear memory by modulating neuronal activity in the basolateral amygdala and infralimbic cortex. | Impairment in extinction of cued fear memory in syntenin-1 knockout mice.
Talukdar G, Inoue R, Yoshida T, Mori H. | 09/21/2019 |
| These findings demonstrate that syntenin promotes VEGF signaling and, through its PDZ-dependent interaction with ephrin-B2, enhances VEGF-mediated VEGFR2 endocytosis and subsequent downstream signaling and angiogenesis in endothelial cells | Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells.
Tae N, Lee S, Kim O, Park J, Na S, Lee JH., Free PMC Article | 04/21/2018 |
| Present study is the first demonstration of the relevance of MDA-9/Syntenin expression in regulating inflammation and immunosuppression in the microenvironment thereby impacting tumor growth and metastasis in mouse melanoma model. | Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.
Das SK, Guo C, Pradhan AK, Bhoopathi P, Talukdar S, Shen XN, Emdad L, Subler MA, Windle JJ, Sarkar D, Wang XY, Fisher PB., Free PMC Article | 01/6/2018 |
| Syntenin-1 negatively regulates the intestinal immunoglobulin production and has a function to maintain the intestinal homeostasis in vivo. | Increased production of intestinal immunoglobulins in Syntenin-1-deficient mice.
Tamura K, Ikutani M, Yoshida T, Tanaka-Hayashi A, Yanagibashi T, Inoue R, Nagai Y, Adachi Y, Miyawaki T, Takatsu K, Mori H. | 01/23/2016 |
| ALCAM stably interacts with actin by binding to syntenin-1 and ezrin. | Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton.
Tudor C, te Riet J, Eich C, Harkes R, Smisdom N, Bouhuijzen Wenger J, Ameloot M, Holt M, Kanger JS, Figdor CG, Cambi A, Subramaniam V., Free PMC Article | 06/28/2014 |
| Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways. | Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.
Ju R, Zhuang ZW, Zhang J, Lanahan AA, Kyriakides T, Sessa WC, Simons M., Free PMC Article | 03/22/2014 |
| MDA-9/syntenin may play a prominent role during normal mouse development in the context of cell proliferation as well as differentiation through modulating multiple signaling pathways as a crucial adaptor protein. | Expression patterns of MDA-9/syntenin during development of the mouse embryo.
Jeon HY, Das SK, Dasgupta S, Emdad L, Sarkar D, Kim SH, Lee SG, Fisher PB., Free PMC Article | 11/16/2013 |
| syntenin plays a role in the migration of oligodendroglial precursors, and we suggest that NG2-syntenin-1 interactions contribute to this | Interaction of syntenin-1 and the NG2 proteoglycan in migratory oligodendrocyte precursor cells.
Chatterjee N, Stegmüller J, Schätzle P, Karram K, Koroll M, Werner HB, Nave KA, Trotter J. | 01/21/2010 |
| Syntenin-1 may function as a scaffolding protein coupling CD6 and other lymphocyte receptors to cytoskeleton and/or signaling effectors during immunologic synapse maturation | The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains.
Gimferrer I, Ibáñez A, Farnós M, Sarrias MR, Fenutría R, Roselló S, Zimmermann P, David G, Vives J, Serra-Pagès C, Lozano F. | 01/21/2010 |
| Complex of Unc51.1/SynGAP1/Syntenin governs axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons | Role of Unc51.1 and its binding partners in CNS axon outgrowth.
Tomoda T, Kim JH, Zhan C, Hatten ME., Free PMC Article | 01/21/2010 |