U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PGK1 phosphoglycerate kinase 1 [ Homo sapiens (human) ]

    Gene ID: 5230, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Acetylation of PGK1 at lysine 323 promotes glycolysis, cell proliferation, and metastasis in luminal A breast cancer cells.

    Acetylation of PGK1 at lysine 323 promotes glycolysis, cell proliferation, and metastasis in luminal A breast cancer cells.
    Gao X, Pan T, Gao Y, Zhu W, Liu L, Duan W, Han C, Feng B, Yan W, Song Q, Liu Y, Yue L., Free PMC Article

    10/4/2024
    Hypoxia-induced downregulation of PGK1 crotonylation promotes tumorigenesis by coordinating glycolysis and the TCA cycle.

    Hypoxia-induced downregulation of PGK1 crotonylation promotes tumorigenesis by coordinating glycolysis and the TCA cycle.
    Guo Z, Zhang Y, Wang H, Liao L, Ma L, Zhao Y, Yang R, Li X, Niu J, Chu Q, Fu Y, Li B, Yang C., Free PMC Article

    08/23/2024
    The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer.

    The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer.
    Tian T, Leng Y, Tang B, Dong X, Ren Q, Liang J, Liu T, Liu Y, Feng W, Liu S, Zhou Y, Zhao H, Shen L., Free PMC Article

    06/26/2024
    PUM1 and PGK1 are Favorable Housekeeping Genes over Established Biodosimetry-related Housekeeping Genes such as HPRT1, ITFG1, DPM1, MRPS5, 18S rRNA and Others after Radiation Exposure.

    PUM1 and PGK1 are Favorable Housekeeping Genes over Established Biodosimetry-related Housekeeping Genes such as HPRT1, ITFG1, DPM1, MRPS5, 18S rRNA and Others after Radiation Exposure.
    Muhtadi R, Stewart S, Bunert F, Fatanmi OO, Wise SY, Gärtner C, Motzke S, Ruf C, Ostheim P, Schüle S, Schwanke D, Singh VK, Port M, Abend M.

    06/5/2024
    CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation.

    CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation.
    Zhang Y, Wang X, Liu W, Lei T, Qiao T, Feng W, Song W., Free PMC Article

    03/13/2024
    PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis.

    PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis.
    Liu H, Chen X, Wang P, Chen M, Deng C, Qian X, Bai J, Li Z, Yu X., Free PMC Article

    02/26/2024
    RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA.

    RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA.
    Wang X, Liang C, Wang S, Ma Q, Pan X, Ran A, Qin C, Huang B, Yang F, Liu Y, Zhang Y, Ren J, Ning H, Li H, Jiang Y, Xiao B., Free PMC Article

    02/9/2024
    Upregulation of mitochondrial PGK1 by ROS-TBC1D15 pathway promotes neuronal death after oxygen-glucose deprivation/reoxygenation injury.

    Upregulation of mitochondrial PGK1 by ROS-TBC1D15 pathway promotes neuronal death after oxygen-glucose deprivation/reoxygenation injury.
    Chen S, Wang H, Chen J, Cheng J, Gao J, Chen S, Yao X, Sun J, Ren J, Li S, Che F, Wan Q.

    01/30/2024
    SNHG17 alters anaerobic glycolysis by resetting phosphorylation modification of PGK1 to foster pro-tumor macrophage formation in pancreatic ductal adenocarcinoma.

    SNHG17 alters anaerobic glycolysis by resetting phosphorylation modification of PGK1 to foster pro-tumor macrophage formation in pancreatic ductal adenocarcinoma.
    Lin J, Liu Y, Liu P, Qi W, Liu J, He X, Liu Q, Liu Z, Yin J, Lin J, Bao H, Lin J., Free PMC Article

    12/20/2023
    H19 encourages aerobic glycolysis and cell growth in gastric cancer cells through the axis of microRNA-19a-3p and phosphoglycerate kinase 1.

    H19 encourages aerobic glycolysis and cell growth in gastric cancer cells through the axis of microRNA-19a-3p and phosphoglycerate kinase 1.
    Chen S, Wang H, Xu P, Dang S, Tang Y., Free PMC Article

    10/13/2023
    N[6]-methyladenosine reader YTHDF3 contributes to the aerobic glycolysis of osteosarcoma through stabilizing PGK1 stability.

    N(6)-methyladenosine reader YTHDF3 contributes to the aerobic glycolysis of osteosarcoma through stabilizing PGK1 stability.
    Liu D, Li Z, Zhang K, Lu D, Zhou D, Meng Y.

    07/20/2023
    Comprehensive analysis of lncRNA-mRNA co-expression networks in HPV-driven cervical cancer reveals the pivotal function of LINC00511-PGK1 in tumorigenesis.

    Comprehensive analysis of lncRNA-mRNA co-expression networks in HPV-driven cervical cancer reveals the pivotal function of LINC00511-PGK1 in tumorigenesis.
    Xin X, Jia-Yin Y, Jun-Yang H, Rui W, Xiong-Ri K, Long-Rui D, Liu J, Jue-Yu Z.

    05/15/2023
    PGK1 modulates balance between pro- and anti-inflammatory cytokines by interacting with ITI-H4.

    PGK1 modulates balance between pro- and anti-inflammatory cytokines by interacting with ITI-H4.
    Park HB, Choi BC, Baek KH.

    04/7/2023
    Circular RNA circHMCU promotes breast tumorigenesis through miR-4458/PGK1 regulatory cascade.

    Circular RNA circHMCU promotes breast tumorigenesis through miR-4458/PGK1 regulatory cascade.
    Qiu S, Zou L, Qiu R, Wang X., Free PMC Article

    03/24/2023
    Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core.

    Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core.
    Pacheco-García JL, Loginov DS, Naganathan AN, Vankova P, Cano-Muñoz M, Man P, Pey AL., Free PMC Article

    10/22/2022
    Long non-coding RNA NRSN2-AS1, transcribed by SOX2, promotes progression of esophageal squamous cell carcinoma by regulating the ubiquitin-degradation of PGK1.

    Long non-coding RNA NRSN2-AS1, transcribed by SOX2, promotes progression of esophageal squamous cell carcinoma by regulating the ubiquitin-degradation of PGK1.
    Xu T, Yan Z, Lu J, Chen L, Li X, Li Y, Dong Z, Guo W.

    10/1/2022
    The basic functions of phosphoglycerate kinase 1 and its roles in cancer and other diseases.

    The basic functions of phosphoglycerate kinase 1 and its roles in cancer and other diseases.
    Liu H, Wang X, Shen P, Ni Y, Han X.

    04/16/2022
    PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis.

    PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis.
    He Y, Wang X, Lu W, Zhang D, Huang L, Luo Y, Xiong L, Li H, Zhang P, Li Q, Liang S., Free PMC Article

    04/16/2022
    PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.

    PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
    Zhang T, Wang Y, Yu H, Zhang T, Guo L, Xu J, Wei X, Wang N, Wu Y, Wang X, Huang L., Free PMC Article

    04/16/2022
    HPV16 E6/E7 stabilize PGK1 protein by reducing its poly-ubiquitination in cervical cancer.

    HPV16 E6/E7 stabilize PGK1 protein by reducing its poly-ubiquitination in cervical cancer.
    Liu S, Song L, Yao H, Zhang L.

    04/16/2022
    LncRNA NEAT1 facilitates glioma progression via stabilizing PGK1.

    LncRNA NEAT1 facilitates glioma progression via stabilizing PGK1.
    Liang J, Liu C, Xu D, Xie K, Li A., Free PMC Article

    03/26/2022
    FOXO3A-induced LINC00926 suppresses breast tumor growth and metastasis through inhibition of PGK1-mediated Warburg effect.

    FOXO3A-induced LINC00926 suppresses breast tumor growth and metastasis through inhibition of PGK1-mediated Warburg effect.
    Chu Z, Huo N, Zhu X, Liu H, Cong R, Ma L, Kang X, Xue C, Li J, Li Q, You H, Zhang Q, Xu X., Free PMC Article

    02/12/2022
    Phosphoglycerate kinase 1 silencing by a novel microRNA microRNA-4523 protects human osteoblasts from dexamethasone through activation of Nrf2 signaling cascade.

    Phosphoglycerate kinase 1 silencing by a novel microRNA microRNA-4523 protects human osteoblasts from dexamethasone through activation of Nrf2 signaling cascade.
    Liang JQ, Zhou ZT, Bo L, Tan HN, Hu JH, Tan MS., Free PMC Article

    02/5/2022
    Molecular mechanism of glycolytic flux control intrinsic to human phosphoglycerate kinase.

    Molecular mechanism of glycolytic flux control intrinsic to human phosphoglycerate kinase.
    Yagi H, Kasai T, Rioual E, Ikeya T, Kigawa T., Free PMC Article

    01/8/2022
    PGK1 : An Essential Player in Modulating Tumor Metabolism.

    PGK1 : An Essential Player in Modulating Tumor Metabolism.
    Duncan L, Shay C, Teng Y.

    12/25/2021
    firstprevious page of 4 nextlast