| miR-212/132 attenuates OVA-induced airway inflammation by inhibiting mast cells activation through MRGPRX2 and ASAP1. | miR-212/132 attenuates OVA-induced airway inflammation by inhibiting mast cells activation through MRGPRX2 and ASAP1.
Zhang Y, Bai H, Zhang W, Gao J, Gao C, Deng T, Liu X, Sun X, Liu Y, Wang N, Wu Y. | 01/3/2024 |
| ASAP1 Expression in Invasive Breast Cancer and Its Prognostic Role. | ASAP1 Expression in Invasive Breast Cancer and Its Prognostic Role.
Park H, Son H, Cha H, Song K, Bang S, Jee S, Kim H, Myung J, Shin SJ, Cha C, Chung MS, Paik S., Free PMC Article | 09/29/2023 |
| An Uncharacterised lncRNA Coded by the ASAP1 Locus Is Downregulated in Serum of Type 2 Diabetes Mellitus Patients. | An Uncharacterised lncRNA Coded by the ASAP1 Locus Is Downregulated in Serum of Type 2 Diabetes Mellitus Patients.
Barbagallo C, Stella M, Di Mauro S, Scamporrino A, Filippello A, Scionti F, Di Martino MT, Purrello M, Ragusa M, Purrello F, Piro S., Free PMC Article | 09/20/2023 |
| ASAP1 activates the IQGAP1/CDC42 pathway to promote tumor progression and chemotherapy resistance in gastric cancer. | ASAP1 activates the IQGAP1/CDC42 pathway to promote tumor progression and chemotherapy resistance in gastric cancer.
Xie W, Han Z, Zuo Z, Xin D, Chen H, Huang J, Zhu S, Lou H, Yu Z, Chen C, Chen S, Hu Y, Huang J, Zhang F, Ni Z, Shen X, Xue X, Lin K., Free PMC Article | 02/23/2023 |
| Polymorphisms in the ASAP1 and SP110 Genes and Its Association with the Susceptibility to Pulmonary Tuberculosis in a Mongolian Population. | Polymorphisms in the ASAP1 and SP110 Genes and Its Association with the Susceptibility to Pulmonary Tuberculosis in a Mongolian Population.
Cui X, Yuan T, Ning P, Han J, Liu Y, Feng J, Lian F, Hao M, Dong L, Hao J, Xing L, Wu C., Free PMC Article | 10/22/2022 |
| Clinicopathological Implications of ASAP1 Expression in Hepatocellular Carcinoma. | Clinicopathological Implications of ASAP1 Expression in Hepatocellular Carcinoma.
Bang S, Jee S, Son H, Cha H, Sim J, Kim Y, Park H, Myung J, Kim H, Paik S., Free PMC Article | 10/1/2022 |
| Loss of ASAP1 in the MMTV-PyMT model of luminal breast cancer activates AKT, accelerates tumorigenesis, and promotes metastasis. | Loss of ASAP1 in the MMTV-PyMT model of luminal breast cancer activates AKT, accelerates tumorigenesis, and promotes metastasis.
Schreiber C, Gruber A, Roßwag S, Saraswati S, Harkins S, Thiele W, Foroushani ZH, Munding N, Schmaus A, Rothley M, Dimmler A, Tanaka M, Garvalov BK, Sleeman JP. | 04/30/2022 |
| ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton. | ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Cui J, Chen G, Zhao Z, Wang L, Wen D, Xing L, Wu C. | 01/8/2022 |
| High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer. | High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer.
Tsutaho A, Hashimoto A, Hashimoto S, Hata S, Kachi S, Hirano S, Sabe H., Free PMC Article | 08/14/2021 |
| Circular RNA Sequencing Identifies CircASAP1 as a Key Regulator in Hepatocellular Carcinoma Metastasis. | Circular RNA Sequencing Identifies CircASAP1 as a Key Regulator in Hepatocellular Carcinoma Metastasis.
Hu ZQ, Zhou SL, Li J, Zhou ZJ, Wang PC, Xin HY, Mao L, Luo CB, Yu SY, Huang XW, Cao Y, Fan J, Zhou J. | 05/1/2021 |
| ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation. | ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation.
Zhang S, Luo Q, Feng R, Yang F, Xu Q, Chen X, Yang S. | 04/13/2021 |
| Knockout of ASAP1 induces autophagy in papillary thyroid carcinoma by inhibiting the mTOR signaling pathway. | Knockout of ASAP1 induces autophagy in papillary thyroid carcinoma by inhibiting the mTOR signaling pathway.
Jiang N, Yang Y, Zhao G, Yuan Q, Liu Z, Wang X, Geng Z, Jia M, Zheng J, Lu X, Yue J, Fan Y. | 04/3/2021 |
| The BAR domain of the Arf GTPase-activating protein ASAP1 directly binds actin filaments. | The BAR domain of the Arf GTPase-activating protein ASAP1 directly binds actin filaments.
Chen PW, Billington N, Maron BY, Sload JA, Chinthalapudi K, Heissler SM., Free PMC Article | 02/20/2021 |
| Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression. | Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
He J, McLaughlin RP, van der Beek L, Canisius S, Wessels L, Smid M, Martens JWM, Foekens JA, Zhang Y, van de Water B., Free PMC Article | 11/28/2020 |
| Mutations in the ARF N terminus that reduced binding also reduced GAP activity. We conclude that PIP2 regulates binding of ASAP1's PH domain to the ARF1 N terminus, which may partially regulate GAP activity. | Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.
Roy NS, Jian X, Soubias O, Zhai P, Hall JR, Dagher JN, Coussens NP, Jenkins LM, Luo R, Akpan IO, Hall MD, Byrd RA, Yohe ME, Randazzo PA., Free PMC Article | 06/13/2020 |
| 2 Arf GAPs, ASAP1 and AGAP1, have been found to bind directly to and influence the activity of myosins and kinesins, motor proteins associated with filamentous actin and microtubules, respectively. | Arf GAPs and molecular motors.
Luo R, Reed CE, Sload JA, Wordeman L, Randazzo PA, Chen PW., Free PMC Article | 04/11/2020 |
| rs4733781 A allele of ASAP1 is associated with a decreased risk of tuberculosis in Han Chinese. | A Common Variant of ASAP1 Is Associated with Tuberculosis Susceptibility in the Han Chinese Population.
Chen C, Zhao Q, Shao Y, Li Y, Song H, Li G, Zhu L, Lu W, Xu B., Free PMC Article | 08/31/2019 |
| Histone modifications of certain miRNA loci, such as the miR-183-96-182 cistron, are different between epithelial cells and non-epithelial cells | Epithelial-specific histone modification of the miR-96/182 locus targeting AMAP1 mRNA predisposes p53 to suppress cell invasion in epithelial cells.
Handa H, Hashimoto A, Hashimoto S, Sugino H, Oikawa T, Sabe H., Free PMC Article | 05/18/2019 |
| AMAP1 mediated CCL18-induce activation of NF-kappaB and promoted breast cancer metastasis. | CCL18-dependent translocation of AMAP1 is critical for epithelial to mesenchymal transition in breast cancer.
Li H, Zhang D, Yu J, Liu H, Chen Z, Zhong H, Wan Y. | 12/22/2018 |
| Results indicate that monocyte differentiation involves enhancement of IRES activity, by which protein levels of AMAP1 are primarily upregulated. | IRES-mediated translational control of AMAP1 expression during differentiation of monocyte U937 cells.
Miyata M, Raven JF, Baltzis D, Koromilas AE, Sabe H. | 09/27/2018 |
| Less differentiated embryonal and undifferentiated small hepatoblastoma cells progressively lose EGFR and ASAP1 expression. This trend is exaggerated in unresectable, locally invasive or metastatic tumors. | Loss of EGFR-ASAP1 signaling in metastatic and unresectable hepatoblastoma.
Ranganathan S, Ningappa M, Ashokkumar C, Higgs BW, Min J, Sun Q, Schmitt L, Subramaniam S, Hakonarson H, Sindhi R., Free PMC Article | 06/2/2018 |
| eIF5B promoted hepatocellular carcinoma cell proliferation and migration in vitro and in vivo partly through increasing ASAP1 expression. | eIF5B increases ASAP1 expression to promote HCC proliferation and invasion.
Wang ZG, Zheng H, Gao W, Han J, Cao JZ, Yang Y, Li S, Gao R, Liu H, Pan ZY, Fu SY, Gu FM, Xing H, Ni JS, Yan HL, Ren H, Zhou WP., Free PMC Article | 02/10/2018 |
| results, specifically, the absence of associations of polymorphisms of ASAP1 with tuberculosis (TB) risk, suggest that ASAP1 may not be a susceptibility gene for TB in Western Chinese Han and Tibetan population | No Significant Effect of ASAP1 Gene Variants on the Susceptibility to Tuberculosis in Chinese Population.
Hu X, Peng W, Chen X, Zhao Z, Zhang J, Zhou J, Cai B, Chen J, Zhou Y, Lu X, Ying B., Free PMC Article | 04/1/2017 |
| results support the hypothesis that ASAP1 is a positive regulator of NM2A. | The Arf GTPase-activating Protein, ASAP1, Binds Nonmuscle Myosin 2A to Control Remodeling of the Actomyosin Network.
Chen PW, Jian X, Heissler SM, Le K, Luo R, Jenkins LM, Nagy A, Moss J, Sellers JR, Randazzo PA., Free PMC Article | 08/20/2016 |
| Rab11-FIP3 coordinates the interactions of ASAP1 and Rab11a with Rabin8. | The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting.
Wang J, Deretic D., Free PMC Article | 04/23/2016 |