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    NME1 NME/NM23 nucleoside diphosphate kinase 1 [ Homo sapiens (human) ]

    Gene ID: 4830, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    NME1 and DCC variants are associated with susceptibility and tumor characteristics in Mexican patients with colorectal cancer.

    NME1 and DCC variants are associated with susceptibility and tumor characteristics in Mexican patients with colorectal cancer.
    Márquez-González RM, Saucedo-Sariñana AM, de Jesús Tovar-Jacome C, Barros-Núñez P, Gallegos-Arreola MP, Orozco-Gutiérrez MH, Mariscal-Ramírez I, Pineda-Razo TD, Alcaraz-Wong AA, Marín-Contreras ME, Rosales-Reynoso MA.

    04/2/2024
    NSUN6 Regulates NM23-H1 Expression in an m5C Manner to Affect Epithelial-Mesenchymal Transition in Lung Cancer.

    NSUN6 Regulates NM23-H1 Expression in an m5C Manner to Affect Epithelial-Mesenchymal Transition in Lung Cancer.
    Lu Z, Liu B, Kong D, Zhou X, Pei D, Liu D., Free PMC Article

    03/4/2024
    A Unique Mode of Coenzyme A Binding to the Nucleotide Binding Pocket of Human Metastasis Suppressor NME1.

    A Unique Mode of Coenzyme A Binding to the Nucleotide Binding Pocket of Human Metastasis Suppressor NME1.
    Tossounian MA, Hristov SD, Semelak JA, Yu BYK, Baczynska M, Zhao Y, Estrin DA, Trujillo M, Filonenko V, Gouge J, Gout I., Free PMC Article

    06/13/2023
    Does the Blood-Brain Barrier Integrity Change in Regard to the Onset of Fetal Growth Restriction?

    Does the Blood-Brain Barrier Integrity Change in Regard to the Onset of Fetal Growth Restriction?
    Misan N, Michalak S, Kapska K, Osztynowicz K, Ropacka-Lesiak M, Kawka-Paciorkowska K., Free PMC Article

    02/28/2023
    Extracellular vesicle expansion of PMIS-miR-210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism.

    Extracellular vesicle expansion of PMIS-miR-210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism.
    Eliason S, Hong L, Sweat Y, Chalkley C, Cao H, Liu Q, Qi H, Xu H, Zhan F, Amendt BA., Free PMC Article

    10/8/2022
    Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems.

    Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems.
    Khan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS., Free PMC Article

    10/1/2022
    MicroRNA-139-5p negatively regulates NME1 expression in hepatocellular carcinoma cells.

    MicroRNA-139-5p negatively regulates NME1 expression in hepatocellular carcinoma cells.
    Yang J, Li Z, Pang Y, Zhou T, Sun J, Cheng XY, Zheng WV.

    07/9/2022
    Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis.

    Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis.
    Zhang S, Nelson OD, Price IR, Zhu C, Lu X, Fernandez IR, Weiss RS, Lin H., Free PMC Article

    03/26/2022
    Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.

    Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.
    Lodillinsky C, Fuhrmann L, Irondelle M, Pylypenko O, Li XY, Bonsang-Kitzis H, Reyal F, Vacher S, Calmel C, De Wever O, Bièche I, Lacombe ML, Eiján AM, Houdusse A, Vincent-Salomon A, Weiss SJ, Chavrier P, Boissan M., Free PMC Article

    01/15/2022
    The Potential Role of Human NME1 in Neuronal Differentiation of Porcine Mesenchymal Stem Cells: Application of NB-hNME1 as a Human NME1 Suppressor.

    The Potential Role of Human NME1 in Neuronal Differentiation of Porcine Mesenchymal Stem Cells: Application of NB-hNME1 as a Human NME1 Suppressor.
    Cho JH, Ju WS, Seo SY, Kim BH, Kim JS, Kim JG, Park SJ, Choo YK., Free PMC Article

    12/18/2021
    Regulation of metastasis suppressor NME1 by a key metabolic cofactor coenzyme A.

    Regulation of metastasis suppressor NME1 by a key metabolic cofactor coenzyme A.
    Yu BYK, Tossounian MA, Hristov SD, Lawrence R, Arora P, Tsuchiya Y, Peak-Chew SY, Filonenko V, Oxenford S, Angell R, Gouge J, Skehel M, Gout I., Free PMC Article

    08/21/2021
    Correlation Between Onco-suppressors PTEN and NM23 and Clinical Outcome in Patients With T1 Breast Cancer.

    Correlation Between Onco-suppressors PTEN and NM23 and Clinical Outcome in Patients With T1 Breast Cancer.
    Izzo L, Messineo D, DI Cello P, Nicolanti V, Sterpetti A, Izzo S, Izzo P., Free PMC Article

    07/31/2021
    Association of polymorphisms in metastasis suppressor genes NME1 and KISS1 with breast cancer development and metastasis.

    Association of polymorphisms in metastasis suppressor genes NME1 and KISS1 with breast cancer development and metastasis.
    Antar S, Mokhtar N, Abd Elghaffar MA, Seleem AK.

    07/24/2021
    Granzyme A Participates in the Pathogenesis of Infection-Associated Acute Encephalopathy.

    Granzyme A Participates in the Pathogenesis of Infection-Associated Acute Encephalopathy.
    Yamanaka G, Morichi S, Takamatsu T, Takahashi R, Watanabe Y, Ishida Y, Takeshita M, Morishita N, Kasuga A, Kanou K, Oana S, Suzuki S, Go S, Kashiwagi Y, Kawashima H.

    07/24/2021
    Nm23-H1 inhibits lung cancer bone-specific metastasis by upregulating miR-660-5p targeted SMARCA5.

    Nm23-H1 inhibits lung cancer bone-specific metastasis by upregulating miR-660-5p targeted SMARCA5.
    Ai C, Ma G, Deng Y, Zheng Q, Gen Y, Li W, Li Y, Zu L, Zhou Q., Free PMC Article

    03/13/2021
    The multiple regulation of metastasis suppressor NM23-H1 in cancer.

    The multiple regulation of metastasis suppressor NM23-H1 in cancer.
    Yu L, Wang X, Zhang W, Khan E, Lin C, Guo C.

    03/6/2021
    Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR.

    Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR.
    Puts G, Jarrett S, Leonard M, Matsangos N, Snyder D, Wang Y, Vincent R, Portney B, Abbotts R, McLaughlin L, Zalzman M, Rassool F, Kaetzel D., Free PMC Article

    02/20/2021
    The Potential Functional Roles of NME1 Histidine Kinase Activity in Neuroblastoma Pathogenesis.

    The Potential Functional Roles of NME1 Histidine Kinase Activity in Neuroblastoma Pathogenesis.
    Adam K, Lesperance J, Hunter T, Zage PE., Free PMC Article

    02/13/2021
    Association of NM23 polymorphisms and clinicopathological features and recurrence of invasive pituitary adenomas.

    Association of NM23 polymorphisms and clinicopathological features and recurrence of invasive pituitary adenomas.
    Wang H, Sang W.

    01/9/2021
    Association of HOTAIR (rs920778 and rs1899663) and NME1 (rs16949649 and rs2302254) gene polymorphisms with breast cancer risk in India.

    Association of HOTAIR (rs920778 and rs1899663) and NME1 (rs16949649 and rs2302254) gene polymorphisms with breast cancer risk in India.
    Rajagopal T, Seshachalam A, Akshaya RL, Rathnam KK, Talluri S, Jothi A, Dunna NR.

    10/10/2020
    these data indicate metastasis suppressor activity of NME1 in melanoma is mediated by induction of ITGB3 gene transcription.

    The metastasis suppressor NME1 inhibits melanoma cell motility via direct transcriptional induction of the integrin beta-3 gene.
    Leonard MK, Novak M, Snyder D, Snow G, Pamidimukkala N, McCorkle JR, Yang XH, Kaetzel DM., Free PMC Article

    05/9/2020
    High NME1 expression is associated with metastasis in melanoma.

    NME1 Drives Expansion of Melanoma Cells with Enhanced Tumor Growth and Metastatic Properties.
    Wang Y, Leonard MK, Snyder DE, Fisher ML, Eckert RL, Kaetzel DM., Free PMC Article

    04/18/2020
    miR-146 can promote the proliferation and invasion of breast cancer by targeting NM23-H1

    miR-146a promoted breast cancer proliferation and invasion by regulating NM23-H1.
    Chen J, Jiang Q, Jiang XQ, Li DQ, Jiang XC, Wu XB, Cao YL.

    03/28/2020
    our experiment provided evidence that nm23-H1 can reverse hypoxia induced EMT and stemness through the inhibition of the Wnt/beta-catenin pathway, which may furnish a deeper perspective into the better treatment or prognosis for NSCLC

    Nm23-H1 inhibits hypoxia induced epithelial-mesenchymal transition and stemness in non-small cell lung cancer cells.
    Wu CE, Zhuang YW, Zhou JY, Liu SL, Zou X, Wu J, Wang RP, Shu P.

    02/22/2020
    NME1 promotes non-homologous end joining of DNA double-strand breaks

    Metastasis suppressor NME1 promotes non-homologous end joining of DNA double-strand breaks.
    Xue R, Peng Y, Han B, Li X, Chen Y, Pei H.

    01/11/2020
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