RNA sequencing comparing centenarian and middle-aged women lymphoblastoid cell lines identifies age-related dysregulated expression of genes encoding selenoproteins, heat shock proteins, CD99, and BID. | RNA sequencing comparing centenarian and middle-aged women lymphoblastoid cell lines identifies age-related dysregulated expression of genes encoding selenoproteins, heat shock proteins, CD99, and BID. Voinsky I, Goldenberg-Bogner O, Israel-Elgali I, Volkov H, Puzianowska-Kuźnicka M, Shomron N, Gurwitz D. | 10/31/2024 |
Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis. | Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis. Winschel I, Willing A, Engler JB, Walkenhorst M, Meurs N, Binkle-Ladisch L, Woo MS, Pfeffer LK, Sonner JK, Borgmeyer U, Hagen SH, Grünhagel B, Claussen JM, Altfeld M, Friese MA., Free PMC Article | 08/9/2024 |
CD99 Modulates the Proteomic Landscape of Ewing Sarcoma Cells and Related Extracellular Vesicles. | CD99 Modulates the Proteomic Landscape of Ewing Sarcoma Cells and Related Extracellular Vesicles. De Feo A, Manfredi M, Mancarella C, Maqueda JJ, De Giorgis V, Pignochino Y, Sciandra M, Cristalli C, Donadelli M, Scotlandi K., Free PMC Article | 02/22/2024 |
CD_99 G1 neutrophils modulate osteogenic differentiation of mesenchymal stem cells in the pathological process of ankylosing spondylitis. | CD_99 G1 neutrophils modulate osteogenic differentiation of mesenchymal stem cells in the pathological process of ankylosing spondylitis. Feng X, Wang C, Ji B, Qiao J, Xu Y, Zhu S, Ji Z, Zhou B, Tong W, Xu W., Free PMC Article | 02/21/2024 |
Cell Adhesion Molecule CD99 in Cancer Immunotherapy. | Cell Adhesion Molecule CD99 in Cancer Immunotherapy. Yu F, Liu G, Zhang H, Wang X, Wu Z, Xu Q, Wu Y, Chen D. | 11/1/2023 |
Role of CD99 in regulating homeostasis and differentiation in normal human epidermal keratinocytes. | Role of CD99 in regulating homeostasis and differentiation in normal human epidermal keratinocytes. Wong YL, Okubo T, Uno E, Suda K, Ishii T. | 05/7/2022 |
CD99 in malignant hematopoiesis. | CD99 in malignant hematopoiesis. Ali A, Vaikari VP, Alachkar H., Free PMC Article | 02/19/2022 |
Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99. | Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99. Mattisson J, Danielsson M, Hammond M, Davies H, Gallant CJ, Nordlund J, Raine A, Edén M, Kilander L, Ingelsson M, Dumanski JP, Halvardson J, Forsberg LA., Free PMC Article | 11/6/2021 |
CD99 and polymeric immunoglobulin receptor peptides deregulation in critical COVID-19: A potential link to molecular pathophysiology? | CD99 and polymeric immunoglobulin receptor peptides deregulation in critical COVID-19: A potential link to molecular pathophysiology? Siwy J, Wendt R, Albalat A, He T, Mischak H, Mullen W, Latosinska A, Lübbert C, Kalbitz S, Mebazaa A, Peters B, Stegmayr B, Spasovski G, Wiech T, Staessen JA, Wolf J, Beige J., Free PMC Article | 10/30/2021 |
Tumour cell CD99 regulates transendothelial migration via CDC42 and actin remodelling. | Tumour cell CD99 regulates transendothelial migration via CDC42 and actin remodelling. Mannion AJ, Odell AF, Taylor A, Jones PF, Cook GP., Free PMC Article | 10/30/2021 |
Anti-CD99 scFv-ELP nanoworms for the treatment of acute myeloid leukemia. | Anti-CD99 scFv-ELP nanoworms for the treatment of acute myeloid leukemia. Vaikari VP, Park M, Keossayan L, MacKay JA, Alachkar H., Free PMC Article | 07/10/2021 |
Anti-human CD99 antibody exerts potent antitumor effects in mantle cell lymphoma. | Anti-human CD99 antibody exerts potent antitumor effects in mantle cell lymphoma. Takheaw N, Sittithumcharee G, Kariya R, Kasinrerk W, Okada S., Free PMC Article | 06/5/2021 |
GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth. | GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth. Zhou F, Elzi DJ, Jayabal P, Ma X, Chiu YC, Chen Y, Blackman B, Weintraub ST, Houghton PJ, Shiio Y., Free PMC Article | 05/8/2021 |
Clinical and preclinical characterization of CD99 isoforms in acute myeloid leukemia. | Clinical and preclinical characterization of CD99 isoforms in acute myeloid leukemia. Vaikari VP, Du Y, Wu S, Zhang T, Metzeler K, Batcha AMN, Herold T, Hiddemann W, Akhtari M, Alachkar H., Free PMC Article | 05/8/2021 |
Association of Maternal Regulatory Single Nucleotide Polymorphic CD99 Genotype with Preeclampsia in Pregnancies Carrying Male Fetuses in Ethiopian Women. | Association of Maternal Regulatory Single Nucleotide Polymorphic CD99 Genotype with Preeclampsia in Pregnancies Carrying Male Fetuses in Ethiopian Women. Kelemu T, Erlandsson L, Seifu D, Abebe M, Teklu S, Storry JR, Hansson SR., Free PMC Article | 02/20/2021 |
Data show that nuclear factor erythroid 2 like 2 (Nrf2) induced cisplatin resistance in ovarian cancer cells by promoting T-cell surface glycoprotein E2 (CD99) expression. | Nrf2 induced cisplatin resistance in ovarian cancer by promoting CD99 expression. Wu J, Zhang L, Li H, Wu S, Liu Z. | 06/6/2020 |
The pseudoautosomal region of human X and Y chromosome encoded CD99 protein was predicted to interact with at least 14 proteins encoded on the somatic chromosomes. | Bioinformatics Annotation of Human Y Chromosome-Encoded Protein Pathways and Interactions. Rengaraj D, Kwon WS, Pang MG. | 04/6/2020 |
CD99 and its ligand interaction induced the upregulation of IL-6 and TNF-alpha expression in anti-CD3 monoclonal antibody activated T cells. | Interaction of CD99 and its ligand upregulates IL-6 and TNF-α upon T cell activation. Takheaw N, Earwong P, Laopajon W, Pata S, Kasinrerk W., Free PMC Article | 02/1/2020 |
A new gene regulatory function for MMP-9 in chronic lymphocytic leukemia (CLL). It also identifies CD99 as an MMP-9 target and a novel contributor to CLL cell adhesion, migration and arrest. CD99 thus constitutes a new therapeutic target in CLL, complementary to MMP-9. | MMP-9 affects gene expression in chronic lymphocytic leukemia revealing CD99 as an MMP-9 target and a novel partner in malignant cell migration/arrest. Aguilera-Montilla N, Bailón E, Uceda-Castro R, Ugarte-Berzal E, Santos A, Gutiérrez-González A, Pérez-Sánchez C, Van den Steen PE, Opdenakker G, García-Marco JA, García-Pardo A. | 12/14/2019 |
Authors demonstrated that ligation of CD99 on monocytes by anti-CD99 mAb MT99/3 could mediate T cell hypo-responsiveness. These findings provide the first evidence of the role of CD99 on monocytes that contributes to T cell activation. | Triggering of CD99 on monocytes by a specific monoclonal antibody regulates T cell activation. Laopajon W, Pata S, Takheaw N, Surinkaew S, Khummuang S, Kasinrerk W. | 12/7/2019 |
Most cases stained positive for CD99 and negative for lymphocytic markers. Markers of epithelial differentiation displayed variable results. In all cases tested, characteristic translocations were displayed supporting the diagnosis. | Primary peripheral neuroectodermal tumor (PNET) of the adrenal gland: a rare entity. Koufopoulos N, Kokkali S, Manatakis D, Balalis D, Nasi D, Ardavanis A, Korkolis D, Khaldi L. | 11/23/2019 |
findings demonstrate that high expression levels of CD99 are mainly found in high-risk BCP-ALL, e.g. BCR-ABL1 and CRLF2(Re/Hi) , and that high CD99 mRNA levels are strongly associated with a high frequency of relapse, high proportion of positive for minimal residual disease at day 29 and poor overall survival in paediatric cohorts | CD99 expression is strongly associated with clinical outcome in children with B-cell precursor acute lymphoblastic leukaemia. Chen D, Camponeschi A, Wu Q, Gerasimcik N, Li H, Shen X, Tan Y, Sjögren H, Nordlund J, Lönnerholm G, Abrahamsson J, Fogelstrand L, Mårtensson IL. | 11/2/2019 |
Study showed that isoform 1, of CD99, is exclusively present in human astrocytomas and cell line and regulates functions, such as cytoskeleton remodeling, cell migration, invasion, and adhesion. The present transcriptome data of CD99 silenced GBM cells, suggest that CD99 modulates FAK1/c-Src signaling pathways, related to actin cytoskeleton dynamics. | CD99 Expression in Glioblastoma Molecular Subtypes and Role in Migration and Invasion. Cardoso LC, Soares RDS, Laurentino TS, Lerario AM, Marie SKN, Oba-Shinjo SM., Free PMC Article | 07/6/2019 |
In summary, we established that tumor suppressor CD99 is markedly downregulated in multiple myeloma. | Tumor suppressor CD99 is downregulated in plasma cell neoplasms lacking CCND1 translocation and distinguishes neoplastic from normal plasma cells and B-cell lymphomas with plasmacytic differentiation from primary plasma cell neoplasms. Gao Q, Yellapantula V, Fenelus M, Pichardo J, Wang L, Landgren O, Dogan A, Roshal M., Free PMC Article | 05/25/2019 |
The present findings identify the genetic basis of the erythroid-specific Xg(a)/CD99 blood group phenotypes and reveal the molecular background of their formation. | The molecular genetic background leading to the formation of the human erythroid-specific Xg(a)/CD99 blood groups. Yeh CC, Chang CJ, Twu YC, Chu CC, Liu BS, Huang JT, Hung ST, Chan YS, Tsai YJ, Lin SW, Lin M, Yu LC., Free PMC Article | 04/6/2019 |