| Length and saturation of fatty acids in phosphatidylserine determine the rate of lysozyme aggregation simultaneously altering the structure and toxicity of amyloid oligomers and fibrils. | Length and saturation of fatty acids in phosphatidylserine determine the rate of lysozyme aggregation simultaneously altering the structure and toxicity of amyloid oligomers and fibrils.
Frese A, Goode C, Zhaliazka K, Holman AP, Dou T, Kurouski D., Free PMC Article | 08/14/2023 |
| Characterisation of the structural, dynamic and aggregation properties of the W64R amyloidogenic variant of human lysozyme. | Characterisation of the structural, dynamic and aggregation properties of the W64R amyloidogenic variant of human lysozyme.
Vettore N, Moray J, Brans A, Herman R, Charlier P, Kumita JR, Kerff F, Dobson CM, Dumoulin M. | 01/15/2022 |
| Analyses of displacements resulting from a point mutation in proteins. | Analyses of displacements resulting from a point mutation in proteins.
Carpentier M, Chomilier J. | 08/7/2021 |
| Lysozyme elicits pain during nerve injury by neuronal Toll-like receptor 4 activation and has therapeutic potential in neuropathic pain. | Lysozyme elicits pain during nerve injury by neuronal Toll-like receptor 4 activation and has therapeutic potential in neuropathic pain.
Yadav S, Surolia A. | 08/15/2020 |
| Serum amyloid P component promotes formation of distinct aggregated lysozyme morphologies and reduces toxicity in Drosophila flies expressing human F57I lysozyme. | Serum amyloid P component promotes formation of distinct aggregated lysozyme morphologies and reduces toxicity in Drosophila flies expressing F57I lysozyme.
Bergkvist L, Richards DR, Bernardo-Gancedo A, Kumita JR, Nilsson PR, Brorsson AC., Free PMC Article | 04/11/2020 |
| These results of the RNA-seq experiment show that lysozyme induces transcriptional modulation of the TNF-alpha/IL-1beta pathway genes in U937 monocytes. | Lysozyme-Induced Transcriptional Regulation of TNF-α Pathway Genes in Cells of the Monocyte Lineage.
Bergamo A, Gerdol M, Pallavicini A, Greco S, Schepens I, Hamelin R, Armand F, Dyson PJ, Sava G., Free PMC Article | 04/4/2020 |
| Three AMP genes, histatin 3 (HTN3), alpha-defensin 4 (DEFA4) and lysozyme C (LYZ), presented different expression levels in periodontitis patients compared with healthy subjects. The relative expression level of DEFA4 appeared to be a protective factor against periodontitis. | Antimicrobial peptide gene expression in periodontitis patients: A pilot study.
Jourdain ML, Pierrard L, Kanagaratnam L, Velard F, Sergheraert J, Lefèvre B, Gangloff SC, Braux J. | 09/14/2019 |
| The findings suggest that the F57I mutation affects the aggregation process of lysozyme resulting in the formation of cytotoxic species and that SAP is able to prevent cell death in the F57I flies by preventing accumulation of toxic F57I structures. | Serum Amyloid P Component Ameliorates Neurological Damage Caused by Expressing a Lysozyme Variant in the Central Nervous System of Drosophila melanogaster.
Helmfors L, Bergkvist L, Brorsson AC., Free PMC Article | 07/22/2017 |
| the location of specific mutations is an important factor in determining the native-state dynamical properties of human lysozyme | The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.
Ahn M, Hagan CL, Bernardo-Gancedo A, De Genst E, Newby FN, Christodoulou J, Dhulesia A, Dumoulin M, Robinson CV, Dobson CM, Kumita JR., Free PMC Article | 07/8/2017 |
| rhamnolipid (RL) secreted by Pseudomonas aeruginosa (PA) accelerates proteolysis of lysozyme. | Human Lysozyme Peptidase Resistance Is Perturbed by the Anionic Glycolipid Biosurfactant Rhamnolipid Produced by the Opportunistic Pathogen Pseudomonas aeruginosa.
Andersen KK, Vad BS, Scavenius C, Enghild JJ, Otzen DE. | 05/27/2017 |
| Data show increased levels of lysozyme C (LYZ), lacritin (LACRT) and zinc-alpha-2 glycoprotein 1 (AZGP1) in pooled tear fluid sample from Graves' disease (GD) patients with moderate-to-severe Graves' orbitopathy (GO) compared with GD patients without clinical signs of GO. | Establishment of a tear protein biomarker panel differentiating between Graves' disease with or without orbitopathy.
Aass C, Norheim I, Eriksen EF, Børnick EC, Thorsby PM, Pepaj M., Free PMC Article | 05/27/2017 |
| lysozyme cannot be used as a marker of acinar differentiation in salivary tumors. However, lysozyme expression can be helpful to distinguish mammary analog secretory carcinoma from acinic cell carcinoma | Lysozyme Expression Can be Useful to Distinguish Mammary Analog Secretory Carcinoma from Acinic Cell Carcinoma of Salivary Glands.
Mariano FV, Gómez CA, de Souza do Nascimento J, Dos Santos HT, Egal ES, Montalli VA, Vargas PA, de Almeida OP, Altemani A., Free PMC Article | 04/8/2017 |
| The preliminary results from the milk yield and milk compositions from a naturally lactating transgenic cloned cow 0906 were also tested. These results provide a solid foundation for the large-scale production of rhLZ in the future. | Large-scale production of functional human lysozyme from marker-free transgenic cloned cows.
Lu D, Liu S, Ding F, Wang H, Li J, Li L, Dai Y, Li N., Free PMC Article | 03/18/2017 |
| The purpose of this study is to understand the oral mucosal immune status of cancer patients and to make clear whether antibacterial proteins such as salivary secretory immunoglobulin (SIgA) and lysozyme in saliva were influenced by patients' health status and certain medical treatment therapy. | Salivary Secretory Immunoglobulin (SIgA) and Lysozyme in Malignant Tumor Patients.
Sun H, Chen Y, Zou X, Li Q, Li H, Shu Y, Li X, Li W, Han L, Ge C., Free PMC Article | 02/18/2017 |
| Data show that hen lysozyme aggregates faster than the human lysozyme. | A comparative study of fibrillation kinetics of two homologous proteins under identical solution condition.
Chaudhary AP, Vispute NH, Shukla VK, Ahmad B. | 02/4/2017 |
| the possible relationship between ocular symptomatology, tear volume and tear break-up time (TBUT) and lipocalin, lactoferrin and lysozyme concentrations in the tear film were explored in a group of symptomatic dry-eyed postmenopausal (PM) women. | Tear lipocalin, lysozyme and lactoferrin concentrations in postmenopausal women.
Careba I, Chiva A, Totir M, Ungureanu E, Gradinaru S., Free PMC Article | 05/7/2016 |
| Tear lysozyme, lactoferrin and lipocalin concentrations were determined via electrophoresis and the results for patients with or without eyelid tumors were compared. | Correlations between eyelid tumors and tear lipocalin, lysozyme and lactoferrin concentrations in postmenopausal women.
Careba I, Gradinaru D, Chiva A, Totir M, Ciuluvica R, Gradinaru S, Ungureanu E., Free PMC Article | 04/16/2016 |
| Data show that transgenic hens with stable expression of recombinant human lysozyme proteins can be created by microinjection of lentiviral vectors. | Expression of recombinant human lysozyme in egg whites of transgenic hens.
Cao D, Wu H, Li Q, Sun Y, Liu T, Fei J, Zhao Y, Wu S, Hu X, Li N., Free PMC Article | 01/23/2016 |
| Both the hLF and hLZ were expressed in the mammary gland of bi-transgenic pigs, as detected by western blotting.Interestingly, pig milk containing hLF and hLZ had synergistic antimicrobial activity | Generation of bi-transgenic pigs overexpressing human lactoferrin and lysozyme in milk.
Cui D, Li J, Zhang L, Liu S, Wen X, Li Q, Zhao Y, Hu X, Zhang R, Li N. | 12/5/2015 |
| The determination of the structure of a low-population intermediate in the product release process by human lysozyme, is reported. | Structure of a low-population intermediate state in the release of an enzyme product.
De Simone A, Aprile FA, Dhulesia A, Dobson CM, Vendruscolo M., Free PMC Article | 09/26/2015 |
| Accumulation of pathogenic lysozymes in the endoplasmic reticulum caused ER stress and the unfolded protein response mainly via the IRE1alpha pathway. | Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals.
Kamada Y, Kusakabe T, Sugimoto Y. | 09/5/2015 |
| Hereditary amyloidosis associated with the p.Trp82Arg lysozyme variant in this new family is predominantly associated with mild upper gastrointestinal tract involvement and in some cases with inflammatory bowel disease. | A new family with hereditary lysozyme amyloidosis with gastritis and inflammatory bowel disease as prevailing symptoms.
Jean E, Ebbo M, Valleix S, Benarous L, Heyries L, Grados A, Bernit E, Grateau G, Papo T, Granel B, Daniel L, Harlé JR, Schleinitz N., Free PMC Article | 04/18/2015 |
| Both mRNA and protein levels of lysozyme were significantly higher in patients with biofilm associated chronic rhinosinusitis (CRS) than those with CRS and no biofilm and controls. | Enhanced expressions of lysozyme, SLPI and glycoprotein 340 in biofilm-associated chronic rhinosinusitis.
Dong D, Yulin Z, Yan X, Hongyan Z, Shitao Z, Jia W. | 01/3/2015 |
| Lzm-S can deposit in the systemic vasculature and kidneys in SS, where this deposition could lead to acute organ dysfunction. | Lysozyme, a mediator of sepsis that deposits in the systemic vasculature and kidney as a possible mechanism of acute organ dysfunction.
Gotes J, Kasian K, Jacobs H, Cheng ZQ, Mink SN. | 10/18/2014 |
| Lysozyme functions as an antimicrobial peptide, with antibacterial activity. | Antimicrobial skin peptides and proteins.
Schröder JM, Harder J., Free PMC Article | 10/3/2014 |