Acute contact with profibrotic macrophages mechanically activates fibroblasts via αvβ3 integrin-mediated engagement of Piezo1.
Ezzo M, Spindler K, Wang JB, Lee D, Pecoraro G, Cowen J, Pakshir P, Hinz B., Free PMC Article

Connexin 43 controls metastatic behavior in triple negative breast cancer through TGFβ1-Smad3-intergin αV signaling axis Based on optical image diagnosis.
Fu Y, Sun X, He Q, Gu Z, Jia X, Zhuang Z.

Integrin αVβ1-activated PYK2 promotes the progression of non-small-cell lung cancer via the STAT3-VGF axis.
Wu Z, Jiao M, Shu C, Zhang S, Wang J, Pu J, Zhu J, Zeng Y, Zhu Y, Liu Z., Free PMC Article

Hypoxia-driven heterogeneous expression of α5 integrin in glioblastoma stem cells is linked to HIF-2α.
Messé M, Bernhard C, Foppolo S, Thomas L, Marchand P, Herold-Mende C, Idbaih A, Kessler H, Etienne-Selloum N, Ochoa C, Tambar UK, Elati M, Laquerriere P, Entz-Werle N, Martin S, Reita D, Dontenwill M.

IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer.
Lu H, Ai J, Zheng Y, Zhou W, Zhang L, Zhu J, Zhang H, Wang S., Free PMC Article

Relationship between aggressive features of oral squamous cell carcinoma and the immunoexpression of CX3CR1, CX3CL1 and ITGAV.
Martínez-Flores R, Lozano-Burgos C, Niklander SE, Fernández-Cuya M, Lopes MA, González-Arriagada WA.

hsa_circ_0000518 stimulates the malignant progression of hepatocellular carcinoma via regulating ITGA5 to activate the Warburg effect.
Li J, Qian L, Ge M, Zhao J, Yang Y.

TLN1 synergizes with ITGA5 to ameliorate cardiac microvascular endothelial cell dysfunction.
Wang X, Mao W, Ma X.

Integrin α5 regulates motility of human monocyte-derived Langerhans cells during immune response.
Guo Z, Murakami M, Saito K, Kato H, Toriyama M, Tominaga M, Ishii KJ, Fujita F.

CircRSU1 alleviates LPS-induced human pulmonary microvascular endothelial cell injury by targeting miR-1224-5p/ITGA5 axis.
Cheng Y, Wang F, Guo C, Yuan S, Li J, Zhang Y.

DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
Liu C, Xu J, Fan J, Liu C, Xie W, Kong H.

A Continuous Extension of Gene Set Enrichment Analysis Using the Likelihood Ratio Test Statistics Identifies Vascular Endothelial Growth Factor as a Candidate Pathway for Alzheimer's Disease via ITGA5.
Mahzarnia A, Lutz MW, Badea A., Free PMC Article

Aldo-keto Reductase 1B10 Restrains Cell Migration, Invasion, and Adhesion of Gastric Cancer via Regulating Integrin Subunit Alpha 5.
Yao H, Hu J, Shao Y, Shah Q, Zheng S., Free PMC Article

ITGA5 promotes tumor angiogenesis in cervical cancer.
Xu X, Shen L, Li W, Liu X, Yang P, Cai J., Free PMC Article

The members of the miR-148/152 family inhibit cancer stem cell-like properties in gastric cancer via negative regulation of ITGA5.
Li X, Li L, Wu J., Free PMC Article

ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma.
Shi Y, Shang J, Li Y, Zhong D, Zhang Z, Yang Q, Lai C, Feng T, Yao Y, Huang X., Free PMC Article

AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway.
Sun B, Ding B, Chen Y, Peng C, Chen X., Free PMC Article

Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2.
Li D, Sun A, Zhang L, Ding Z, Yi F, Yang X, Wang Z, Chen X, Liu W, Liu S, Shen H, Miao M, Zhang L, Liu P, Liu Y, Su S, Huang H, Huang C, Hu Z, Zhang H, Zha X, Liu Y., Free PMC Article

ITGA5 Promotes Tumor Progression through the Activation of the FAK/AKT Signaling Pathway in Human Gastric Cancer.
Wang JF, Chen YY, Zhang SW, Zhao K, Qiu Y, Wang Y, Wang JC, Yu Z, Li BP, Wang Z, Chen JQ., Free PMC Article

Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer.
Assidicky R, Tokat UM, Tarman IO, Saatci O, Ersan PG, Raza U, Ogul H, Riazalhosseini Y, Can T, Sahin O., Free PMC Article

LncRNA NEAT1 Enhances Glioma Progression via Regulating the miR-128-3p/ITGA5 Axis.
Chen J, Wang H, Wang J, Niu W, Deng C, Zhou M., Free PMC Article

Long non-coding RNA ABHD11-AS1 promotes colorectal cancer progression and invasion through targeting the integrin subunit alpha 5/focal adhesion kinase/phosphoinositide 3 kinase/Akt signaling pathway.
Luo J, Jiang Y, Wu L, Zhuo D, Zhang S, Jiang X, Sun Y, Huang Y., Free PMC Article

Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells.
Schiesser JV, Loudovaris T, Thomas HE, Elefanty AG, Stanley EG., Free PMC Article

Integrin αVβ1 regulates procollagen I production through a non-canonical transforming growth factor β signaling pathway in human hepatic stellate cells.
Han Z, Ma Y, Cao G, Ma Z, Chen R, Cvijic ME, Cheng D.

Integrin α5 mediates intrinsic cisplatin resistance in three-dimensional nasopharyngeal carcinoma spheroids via the inhibition of phosphorylated ERK /caspase-3 induced apoptosis.
Ngaokrajang U, Janvilisri T, Sae-Ueng U, Prungsak A, Kiatwuthinon P.