| The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation. | The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation.
Hunter EJ, Hamaia SW, Kim PS, Malcor JM, Farndale RW., Free PMC Article | 01/11/2023 |
| Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma. | Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma.
Li X, Wang N, Leng H, Yuan H, Xu L. | 11/26/2022 |
| Erianin Controls Collagen-Mediated Retinal Angiogenesis via the RhoA/ROCK1 Signaling Pathway Induced by the alpha2/beta1 Integrin-Collagen Interaction. | Erianin Controls Collagen-Mediated Retinal Angiogenesis via the RhoA/ROCK1 Signaling Pathway Induced by the alpha2/beta1 Integrin-Collagen Interaction.
Li X, Liu X, Xing Y, Zeng L, Liu X, Shen H, Ma J., Free PMC Article | 02/19/2022 |
| The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1. | The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1.
Singh JP, Li Y, Chen YY, Hsu SD, Page R, Peti W, Meng TC., Free PMC Article | 01/29/2022 |
| CD49a Identifies Polyfunctional Memory CD8 T Cell Subsets that Persist in the Lungs After Influenza Infection. | CD49a Identifies Polyfunctional Memory CD8 T Cell Subsets that Persist in the Lungs After Influenza Infection.
Reilly EC, Sportiello M, Emo KL, Amitrano AM, Jha R, Kumar ABR, Laniewski NG, Yang H, Kim M, Topham DJ., Free PMC Article | 01/1/2022 |
| Nanofluorescence Probes to Detect miR-192/Integrin Alpha 1 and Their Correlations with Retinoblastoma. | Nanofluorescence Probes to Detect miR-192/Integrin Alpha 1 and Their Correlations with Retinoblastoma.
Gao Y, Zhang H, Zhao S, He D, Gu C. | 12/25/2021 |
| An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease. | An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease.
Brubaker DK, Kumar MP, Chiswick EL, Gregg C, Starchenko A, Vega PN, Southard-Smith AN, Simmons AJ, Scoville EA, Coburn LA, Wilson KT, Lau KS, Lauffenburger DA., Free PMC Article | 11/6/2021 |
| Alginate oligosaccharide protects endothelial cells against oxidative stress injury via integrin-alpha/FAK/PI3K signaling. | Alginate oligosaccharide protects endothelial cells against oxidative stress injury via integrin-α/FAK/PI3K signaling.
Zhao J, Han Y, Wang Z, Zhang R, Wang G, Mao Y. | 07/31/2021 |
| These data indicate that integrin alpha2 signaling may have an increased osteogenic effect relative to integrin alpha1 . | Influence of collagen-based integrin α(1) and α(2) mediated signaling on human mesenchymal stem cell osteogenesis in three dimensional contexts.
Becerra-Bayona SM, Guiza-Arguello VR, Russell B, Höök M, Hahn MS., Free PMC Article | 10/5/2019 |
| VLA1-collagen recognition is regulated by magnesium. | Magnesium Activates Microsecond Dynamics to Regulate Integrin-Collagen Recognition.
Nunes AM, Minetti CASA, Remeta DP, Baum J., Free PMC Article | 08/10/2019 |
| ITGA1 promotes therapy resistance and metastatic potential in pancreatic cancer. | ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer.
Gharibi A, La Kim S, Molnar J, Brambilla D, Adamian Y, Hoover M, Hong J, Lin J, Wolfenden L, Kelber JA., Free PMC Article | 04/27/2019 |
| IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells. | IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells.
Hydes T, Noll A, Salinas-Riester G, Abuhilal M, Armstrong T, Hamady Z, Primrose J, Takhar A, Walter L, Khakoo SI., Free PMC Article | 03/16/2019 |
| It was found that the levels of integrin alpha1 and VE-cadherin mRNA increased during co-culturing of activated endothelium cells with mesenchymal stromal cells. | Expression of Adhesion Molecules in Activated Endothelium after Interaction with Mesenchymal Stromal Cells.
Zhidkova OV, Andreeva ER, Buravkova LB. | 09/1/2018 |
| Results suggest that genetic variants in ITGA1 may be involved in the etiology of attention-deficit/hyperactivity disorder and the single-nucleotide polymorphisms -set based analysis is a promising strategy for the detection of underlying genetic risk factors. | The SNP-set based association study identifies ITGA1 as a susceptibility gene of attention-deficit/hyperactivity disorder in Han Chinese.
Liu L, Zhang L, Li HM, Wang ZR, Xie XF, Mei JP, Jin JL, Shi J, Sun L, Li SC, Tan YL, Yang L, Wang J, Yang HM, Qian QJ, Wang YF., Free PMC Article | 05/12/2018 |
| favors adhesive over migratory fibroblast phenotype | Blocking α1-integrin reverts the adhesive phenotype of adult fibroblasts towards a foetal-like migratory phenotype.
Walraven M, van Vliet SJ, Beelen RH, van Egmond M, Ulrich MM. | 02/17/2018 |
| Data suggest that the residue volume at phenylalanine (Phe) in alpha1-helix is critical for alpha(L)/beta(2) integrin (CD49a/CD18) activation and binding with soluble/immobilized ICAM1 (intercellular cell adhesion molecule 1). | A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding.
Wang Z, Thinn AMM, Zhu J., Free PMC Article | 01/27/2018 |
| Studies suggest there are two nonoverlapping NK cell populations that are potentially liver resident in humans: CD49a+ NK cells and Eomes hi. | Liver-Resident NK Cells: The Human Factor.
Male V. | 01/20/2018 |
| A range of affinities from almost no interaction to the relatively high avidity that characterizes alphaIIbbeta3 is seen between various alpha subunits and beta1 transmembrane and cytosolic domains. | Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function.
Lu Z, Mathew S, Chen J, Hadziselimovic A, Palamuttam R, Hudson BG, Fässler R, Pozzi A, Sanders CR, Zent R., Free PMC Article | 11/18/2017 |
| a comparative study between the wild type integrin alpha1 I and a gain-of-function E317A mutant. NMR HDX results suggest a relationship between regions exhibiting a reduced local stability in the unbound I domain and those that undergo significant conformational changes upon binding. | Intrinsic local destabilization of the C-terminus predisposes integrin α1 I domain to a conformational switch induced by collagen binding.
Nunes AM, Zhu J, Jezioro J, Minetti CA, Remeta DP, Farndale RW, Hamaia SW, Baum J., Free PMC Article | 07/15/2017 |
| MYC is a key regulating factor for the control of ITGA1 expression in colorectal cancer. | Integrin α1β1 expression is controlled by c-MYC in colorectal cancer cells.
Boudjadi S, Carrier JC, Groulx JF, Beaulieu JF., Free PMC Article | 09/3/2016 |
| Data indicate that CD49a(+) NK cells retain their phenotype after expansion in long-term in vitro cultures. | Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson MA, Kekäläinen E, Johansson H, Mjösberg J, Westgren M, Lankisch TO, Wedemeyer H, Ellis EC, Ljunggren HG, Michaëlsson J, Björkström NK. | 06/20/2015 |
| Integrin alpha1 and beta4 are downregulated, following Dendrofalconerol A treatment, in H460 cells. | Dendrofalconerol A suppresses migrating cancer cells via EMT and integrin proteins.
Pengpaeng P, Sritularak B, Chanvorachote P. | 03/21/2015 |
| miR-101:DNMT-3B interaction modulates integrin alpha-1 epigenetically. | Two non-coding RNAs, MicroRNA-101 and HOTTIP contribute cartilage integrity by epigenetic and homeotic regulation of integrin-α1.
Kim D, Song J, Han J, Kim Y, Chun CH, Jin EJ. | 12/6/2014 |
| 17-beta-estradiol modulates connexins and integrins as well as ER-beta expression induced by high frequency electromagnetic fields. | 17-β-Estradiol counteracts the effects of high frequency electromagnetic fields on trophoblastic connexins and integrins.
Cervellati F, Valacchi G, Lunghi L, Fabbri E, Valbonesi P, Marci R, Biondi C, Vesce F., Free PMC Article | 08/16/2014 |
| CD49a promoted Con A-induced hepatitis through enhancing inflammatory cytokine production (IFN-gamma and IL-17A) by CD4(+) T and invariant natural killer T cells. | CD49a promotes T-cell-mediated hepatitis by driving T helper 1 cytokine and interleukin-17 production.
Chen Y, Peng H, Chen Y, Wei H, Sun R, Tian Z., Free PMC Article | 05/17/2014 |