Association of IRS1 gene Pro512Ala polymorphism with nonalcoholic fatty liver disease.
Asadi A, Rostami M, Shafiee R, Ardalani A, Dehghanitafti A, Golshadi Z, Kohansal K, Ghasemi F, Najafi M, Mahmoudi T, Rezamand G, Dabiri R, Nobakht H, Farahani H, Tabaeian SP., Free PMC Article

Sex differences in adipose insulin resistance are linked to obesity, lipolysis and insulin receptor substrate 1.
Arner P, Viguerie N, Massier L, Rydén M, Astrup A, Blaak E, Langin D, Andersson DP., Free PMC Article

sh- Ambra1 inhibits IRS-1/PI3K/Akt signalling pathway to reduce autophagy in gestational diabetes.
Qu X, Li XY, Feng Y, Wang X, Li L, Wang YP, Chu YL.

IRS1 promotes thyroid cancer metastasis through EMT and PI3K/AKT pathways.
Yu F, Huang D, Kuang Y, Dong J, Han Q, Zhou J, Teng X.

High risk genetic variants of human insulin receptor substrate 1(IRS1) infer structural instability and functional interference.
Bhattacharjee A, Pranto SMAM, Ahammad I, Chowdhury ZM, Juliana FM, Das KC, Keya CA, Salimullah M.

Influence of polymorphisms in IRS1, IRS2, MC3R, and MC4R on metabolic and inflammatory status and food intake in Brazilian adults: An exploratory pilot study.
Fajardo CM, Cerda A, Bortolin RH, de Oliveira R, Stefani TIM, Dos Santos MA, Braga AA, Dorea EL, Bernik MMS, Bastos GM, Sampaio MF, Damasceno NRT, Verlengia R, de Oliveira MRM, Hirata MH, Hirata RDC.

Gender Differences of Gly972Arg Polymorphism of the IRS-1 Gene Related to Cardiovascular Disease Risk Factors Among Indonesians.
Sukmawan R, Akip HM, Wulandari P, Bobians ET, Koencoro BAS, Danny SS, Ambari AM, Raharjo SB, Widyantoro B, Adiarto S.

Association of IRS-1 and IRS-2 polymorphisms with predisposition to type-2 diabetes (T2D): a meta-analysis and trial sequential analysis.
Luo Q, Ling Z, Huang X, Zuo Y.

Long Non-coding RNA SPAG5-AS1 Attenuates Diabetic Retinal Vascular Dysfunction by Inhibiting Human Retinal Microvascular Endothelial Cell Proliferation, Migration, and Tube Formation by Regulating the MicroRNA-1224-5p/IRS-1 Axis.
Su X, Yang X, Liu H.

Overexpression of Insulin Receptor Substrate 1 (IRS1) Relates to Poor Prognosis and Promotes Proliferation, Stemness, Migration, and Oxidative Stress Resistance in Cholangiocarcinoma.
Kaewlert W, Sakonsinsiri C, Lert-Itthiporn W, Ungarreevittaya P, Pairojkul C, Pinlaor S, Murata M, Thanan R., Free PMC Article

Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice.
Zhang X, Varma S, Yee D., Free PMC Article

Insulin Receptor Substrate 1 Gly972Arg (rs1801278) Polymorphism Is Associated with Obesity and Insulin Resistance in Kashmiri Women with Polycystic Ovary Syndrome.
Rasool SUA, Nabi M, Ashraf S, Amin S., Free PMC Article

MicroRNA-7 Regulates Insulin Signaling Pathway by Targeting IRS1, IRS2, and RAF1 Genes in Gestational Diabetes Mellitus.
Bhushan R, Rani A, Gupta D, Ali A, Dubey PK.

GST T1, M1, and IRS-1 G972R Genetic Variants Association to Gestational Diabetes Mellitus (GDM) in Egyptian Women: Linkage to Maternal Hyperglycemia.
Barseem NF, Khattab E, Dawood R, Mohamed S.

Insulin receptor substrate 1(IRS1) is related with lymph node metastases and prognosis in esophageal squamous cell carcinoma.
Lei Y, Jamal M, Zeng X, He H, Xiao D, Zhang C, Zhang X, Tan H, Xie S, Zhang Q.

THE RELATIONSHIPS OF IRS-1 POLYMORPHISM WITH HEMODYNAMIC DISORDERS IN HYPERTENSIVE PATIENTS DEPENDING ON BODY WEIGHT AND METABOLIC COMORBIDITY.
Psarova V, Kochuieva M, Gogunska I, Shchur O, Kochuiev G, Tymchenko H.

Insulin Receptor Substrate 1 Gene and Glucose Metabolism Characteristics in Type 2 Diabetes Mellitus with Comorbidities.
Marushchak M, Krynytska I., Free PMC Article

The association between sarcopenia susceptibility and polymorphisms of FTO, ACVR2B, and IRS1 in Tibetans.
Zhang X, Ye L, Li X, Chen Y, Jiang Y, Li W, Wen Y., Free PMC Article

Long noncoding RNA ADIRF antisense RNA 1 upregulates insulin receptor substrate 1 to decrease the aggressiveness of osteosarcoma by sponging microRNA-761.
Xu L, Tan Y, Xu F, Zhang Y., Free PMC Article

miR-410-3P inhibits adipocyte differentiation by targeting IRS-1 in cancer-associated cachexia patients.
Sun D, Ding Z, Shen L, Yang F, Han J, Wu G., Free PMC Article

TGF-β Induction of miR-143/145 Is Associated to Exercise Response by Influencing Differentiation and Insulin Signaling Molecules in Human Skeletal Muscle.
Dreher SI, Höckele S, Huypens P, Irmler M, Hoffmann C, Jeske T, Hastreiter M, Moller A, Birkenfeld AL, Häring HU, Peter A, Beckers J, Hrabě de Angelis M, Weigert C., Free PMC Article

MicroRNA-21 deficiency suppresses prostate cancer progression through downregulation of the IRS1-SREBP-1 signaling pathway.
Kanagasabai T, Li G, Shen TH, Gladoun N, Castillo-Martin M, Celada SI, Xie Y, Brown LK, Mark ZA, Ochieng J, Ballard BR, Cordon-Cardo C, Adunyah SE, Jin R, Matusik RJ, Chen Z.

Curcumin represses mTORC1 signaling in Caco-2 cells by a two-sided mechanism involving the loss of IRS-1 and activation of AMPK.
Kaur H, Moreau R.

Differential expression of insulin receptor substrate-1(IRS-1) in visceral and subcutaneous adipose depots of morbidly obese subjects undergoing bariatric surgery in a tertiary care center in north India; SNP analysis and correlation with metabolic profile.
Sharma M, Aggarwal S, Nayar U, Vikram NK, Misra A, Luthra K.

Sofosbuvir improves HCV-induced insulin resistance by blocking IRS1 degradation.
Rey E, Ampuero J, Molina-Jiménez F, Marañón P, García-García Y, Múñoz-Hernández R, Romero-Gómez M, García-Monzón C, Majano P, González-Rodríguez Á., Free PMC Article