| [Characteristics of gastric neuroendocrine tumors and the PDX-1 transcription factor expression]. | [Characteristics of gastric neuroendocrine tumors and the PDX-1 transcription factor expression].
Gurevich LE, Vasyukova OA, Mikhaleva LM, Bondarenko EV, Shikina VE. | 10/10/2024 |
| RFX6 regulates human intestinal patterning and function upstream of PDX1. | RFX6 regulates human intestinal patterning and function upstream of PDX1.
Sanchez JG, Rankin S, Paul E, McCauley HA, Kechele DO, Enriquez JR, Jones NH, Greeley SAW, Letourneau-Frieberg L, Zorn AM, Krishnamurthy M, Wells JM., | 05/13/2024 |
| Novel pathogenic PDX1 gene variant in a Korean family with maturity-onset diabetes of the young. | Novel pathogenic PDX1 gene variant in a Korean family with maturity-onset diabetes of the young.
Kim H, Kim HY, Kim JH, Seo SH, Park KU., Free PMC Article | 01/12/2024 |
| Repression of latent NF-kappaB enhancers by PDX1 regulates beta cell functional heterogeneity. | Repression of latent NF-κB enhancers by PDX1 regulates β cell functional heterogeneity.
Weidemann BJ, Marcheva B, Kobayashi M, Omura C, Newman MV, Kobayashi Y, Waldeck NJ, Perelis M, Lantier L, McGuinness OP, Ramsey KM, Stein RW, Bass J., Free PMC Article | 01/10/2024 |
| miR-765 targeting PDX1 impairs pancreatic beta-cell function to induce type 2 diabetes. | miR-765 targeting PDX1 impairs pancreatic β-cell function to induce type 2 diabetes.
Zheng L, Wang Y, Li Y, Li L, Wang X, Li Y. | 11/16/2023 |
| Significance of pancreatic duodenal homeobox-1 (PDX-1) genetic polymorphism in insulin secretion in Japanese patients with type 2 diabetes. | Significance of pancreatic duodenal homeobox-1 (PDX-1) genetic polymorphism in insulin secretion in Japanese patients with type 2 diabetes.
Okura T, Nakamura R, Ito Y, Kitao S, Anno M, Endo S, Taneda N, Matsumoto K, Shoji K, Okura H, Matsuzawa K, Izawa S, Ueta E, Kato M, Imamura T, Taniguchi SI, Yamamoto K., Free PMC Article | 02/11/2023 |
| Biophysical insights into glucose-dependent transcriptional regulation by PDX1. | Biophysical insights into glucose-dependent transcriptional regulation by PDX1.
Usher ET, Showalter SA., Free PMC Article | 01/11/2023 |
| STAT3 suppression and beta-cell ablation enhance alpha-to-beta reprogramming mediated by Pdx1. | STAT3 suppression and β-cell ablation enhance α-to-β reprogramming mediated by Pdx1.
Wakabayashi Y, Miyatsuka T, Miura M, Himuro M, Taguchi T, Iida H, Nishida Y, Fujitani Y, Watada H., Free PMC Article | 12/31/2022 |
| Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer. | Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer.
Lee Y, Dho SH, Lee J, Hwang JH, Kim M, Choi WY, Lee JY, Lee J, Chang W, Lee MY, Choi J, Kim TY, Kim LK., Free PMC Article | 04/23/2022 |
| TAZ promotes PDX1-mediated insulinogenesis. | TAZ promotes PDX1-mediated insulinogenesis.
Jeong MG, Kim HK, Lee G, Won HY, Yoon DH, Hwang ES., Free PMC Article | 03/26/2022 |
| Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated beta-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes. | Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.
de Jesus DS, Mak TCS, Wang YF, von Ohlen Y, Bai Y, Kane E, Chabosseau P, Chahrour CM, Distaso W, Salem V, Tomas A, Stoffel M, Rutter GA, Latreille M., Free PMC Article | 03/26/2022 |
| Knockdown of PDX1 enhances the osteogenic differentiation of ADSCs partly via activation of the PI3K/Akt signaling pathway. | Knockdown of PDX1 enhances the osteogenic differentiation of ADSCs partly via activation of the PI3K/Akt signaling pathway.
Liu F, Chen GD, Fan LK., Free PMC Article | 03/19/2022 |
| PDX1 and MC4R genetic polymorphisms are associated with type 2 diabetes mellitus risk in the Chinese Han population. | PDX1 and MC4R genetic polymorphisms are associated with type 2 diabetes mellitus risk in the Chinese Han population.
Wang N, Tong R, Xu J, Tian Y, Pan J, Cui J, Chen H, Peng Y, Fei S, Yang S, Wang L, Yao J, Cui W., Free PMC Article | 03/5/2022 |
| Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function. | Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
Zhang M, Yang C, Zhu M, Qian L, Luo Y, Cheng H, Geng R, Xu X, Qian C, Liu Y. | 02/26/2022 |
| Oxidative Stress Leads to beta-Cell Dysfunction Through Loss of beta-Cell Identity. | Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity.
Leenders F, Groen N, de Graaf N, Engelse MA, Rabelink TJ, de Koning EJP, Carlotti F., Free PMC Article | 01/8/2022 |
| PDX1-MODY: A rare missense mutation as a cause of monogenic diabetes. | PDX1-MODY: A rare missense mutation as a cause of monogenic diabetes.
Abreu GM Miss, Tarantino RM, da Fonseca ACP, de Souza RB, Soares CAPD, Cabello PH, Rodacki M, Zajdenverg L, Zembrzuski VM, Campos Junior M. | 08/7/2021 |
| Soluble expression, purification, and secondary structure determination of human PDX1 transcription factor. | Soluble expression, purification, and secondary structure determination of human PDX1 transcription factor.
Narayan G, Sundaravadivelu PK, Agrawal A, Gogoi R, Nagotu S, Thummer RP. | 08/7/2021 |
| miR-1249-5p regulates the osteogenic differentiation of ADSCs by targeting PDX1. | miR-1249-5p regulates the osteogenic differentiation of ADSCs by targeting PDX1.
Yang XM, Song YQ, Li L, Liu DM, Chen GD., Free PMC Article | 07/17/2021 |
| Effect of Sonic hedgehog pathway inhibition on PDX1 expression during pancreatic differentiation of human embryonic stem cells. | Effect of Sonic hedgehog pathway inhibition on PDX1 expression during pancreatic differentiation of human embryonic stem cells.
Pethe PS, Dumasia NP, Bhartiya D. | 06/5/2021 |
| REST Inhibits Direct Reprogramming of Pancreatic Exocrine to Endocrine Cells by Preventing PDX1-Mediated Activation of Endocrine Genes. | REST Inhibits Direct Reprogramming of Pancreatic Exocrine to Endocrine Cells by Preventing PDX1-Mediated Activation of Endocrine Genes.
Elhanani O, Salame TM, Sobel J, Leshkowitz D, Povodovski L, Vaknin I, Kolodkin-Gal D, Walker MD. | 06/5/2021 |
| Alternative Lengthening of Telomeres and Differential Expression of Endocrine Transcription Factors Distinguish Metastatic and Non-metastatic Insulinomas. | Alternative Lengthening of Telomeres and Differential Expression of Endocrine Transcription Factors Distinguish Metastatic and Non-metastatic Insulinomas.
Hackeng WM, Schelhaas W, Morsink FHM, Heidsma CM, van Eeden S, Valk GD, Vriens MR, Heaphy CM, Nieveen van Dijkum EJM, Offerhaus GJA, Dreijerink KMA, Brosens LAA., Free PMC Article | 03/27/2021 |
| Tectorigenin enhances PDX1 expression and protects pancreatic beta-cells by activating ERK and reducing ER stress. | Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.
Yao X, Li K, Liang C, Zhou Z, Wang J, Wang S, Liu L, Yu CL, Song ZB, Bao YL, Zheng LH, Sun Y, Wang G, Huang Y, Yi J, Sun L, Li Y., Free PMC Article | 02/2/2021 |
| Annexin A10 is involved in the induction of pancreatic duodenal homeobox1 in gastric cancer tissue, cells and organoids. | Annexin A10 is involved in the induction of pancreatic duodenal homeobox‑1 in gastric cancer tissue, cells and organoids.
Ishikawa A, Sakamoto N, Honma R, Taniyama D, Fukada K, Hattori T, Sentani K, Oue N, Yanagihara K, Tanabe K, Ohdan H, Yasui W. | 08/22/2020 |
| A novel gene in early childhood diabetes: EDEM2 silencing decreases SLC2A2 and PXD1 expression, leading to impaired insulin secretion. | A novel gene in early childhood diabetes: EDEM2 silencing decreases SLC2A2 and PXD1 expression, leading to impaired insulin secretion.
Alhaidan Y, Christesen HT, Højlund K, Al Balwi MA, Brusgaard K. | 08/13/2020 |
| Point mutations in PDX1 transactivation domain disrupt beta-cell differentiation and insulin secretion. | Point mutations in the PDX1 transactivation domain impair human β-cell development and function.
Wang X, Sterr M, Ansarullah, Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H., Free PMC Article | 04/18/2020 |