| ALDOA coordinates PDE3A through the beta-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations. | ALDOA coordinates PDE3A through the β-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations.
Yeh CY, Cai HY, Kuo HH, Lin YY, He ZJ, Cheng HC, Yang CJ, Huang CF, Chang YC. | 06/26/2024 |
| ID3 is a novel target gene of p53 and modulates lung cancer cell metastasis. | ID3 is a novel target gene of p53 and modulates lung cancer cell metastasis.
Nagasaka M, Miyajima C, Inoue Y, Hashiguchi S, Suzuki Y, Morishita D, Aoki H, Toriuchi K, Katayama R, Aoyama M, Hayashi H. | 04/12/2024 |
| The nuclear factor ID3 endows macrophages with a potent anti-tumour activity. | The nuclear factor ID3 endows macrophages with a potent anti-tumour activity.
Deng Z, Loyher PL, Lazarov T, Li L, Shen Z, Bhinder B, Yang H, Zhong Y, Alberdi A, Massague J, Sun JC, Benezra R, Glass CK, Elemento O, Iacobuzio-Donahue CA, Geissmann F., Free PMC Article | 02/26/2024 |
| Inhibitor of DNA Binding Protein 3 (ID3) and Nuclear Respiratory Factor 1 (NRF1) Mediated Transcriptional Gene Signatures are Associated with the Severity of Cerebral Amyloid Angiopathy. | Inhibitor of DNA Binding Protein 3 (ID3) and Nuclear Respiratory Factor 1 (NRF1) Mediated Transcriptional Gene Signatures are Associated with the Severity of Cerebral Amyloid Angiopathy.
Perez CM, Gong Z, Yoo C, Roy D, Deoraj A, Felty Q. | 02/15/2024 |
| Investigating the ID3/SLC22A4 as immune-related signatures in ischemic stroke. | Investigating the ID3/SLC22A4 as immune-related signatures in ischemic stroke.
Lu D, Cai H, Li Y, Chang W, Liu X, Dai Q, Yu W, Chen W, Qiao G, Xie H, Xiao X, Li Z., Free PMC Article | 01/26/2024 |
| Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1-mediated immune suppression during GVHD. | Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1-mediated immune suppression during GVHD.
Wang Y, He S, Calendo G, Bui T, Tian Y, Lee CY, Zhou Y, Zhao X, Abraham C, Mo W, Chen M, Sanders-Braggs R, Madzo J, Issa JP, Hexner EO, Wiest DL, Reshef R, Xue HH, Zhang Y., Free PMC Article | 01/12/2024 |
| A positive feedback loop between ID3 and PPARgamma via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer. | A positive feedback loop between ID3 and PPARγ via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer.
Huang C, Wang L, Chen H, Fu W, Shao L, Zhou D, Wu J, Ye Y., Free PMC Article | 06/2/2023 |
| Brain infiltration of breast cancer stem cells is facilitated by paracrine signaling by inhibitor of differentiation 3 to nuclear respiratory factor 1. | Brain infiltration of breast cancer stem cells is facilitated by paracrine signaling by inhibitor of differentiation 3 to nuclear respiratory factor 1.
Das JK, Deoraj A, Roy D, Felty Q. | 09/24/2022 |
| Circadian Period 2 (Per2) downregulate inhibitor of differentiation 3 (Id3) expression via PTEN/AKT/Smad5 axis to inhibits glioma cell proliferation. | Circadian Period 2 (Per2) downregulate inhibitor of differentiation 3 (Id3) expression via PTEN/AKT/Smad5 axis to inhibits glioma cell proliferation.
Zhang Y, Hu X, Li H, Yao J, Yang P, Lan Y, Xia H., Free PMC Article | 05/28/2022 |
| Loss of ID3 in pancreatic cancer cells increases DNA damage without impairing MDC1 recruitment to the nuclear foci. | Loss of ID3 in pancreatic cancer cells increases DNA damage without impairing MDC1 recruitment to the nuclear foci.
Xu J, Palestino Dominguez M, Alewine C., Free PMC Article | 05/14/2022 |
| Expression of Id3 represses exhaustion of anti-tumor CD8 T cells in liver cancer. | Expression of Id3 represses exhaustion of anti-tumor CD8 T cells in liver cancer.
Jin Y, Hu P, Sun H, Yang C, Zhai J, Wang Y, Chu X, Sun Z, Wang J, Sun J, Wang J. | 05/7/2022 |
| ID1/ID3 mediate the contribution of skin fibroblasts to local nerve regeneration through Itga6 in wound repair. | ID1/ID3 mediate the contribution of skin fibroblasts to local nerve regeneration through Itga6 in wound repair.
Chen Z, Shen G, Tan X, Qu L, Zhang C, Ma L, Luo P, Cao X, Yang F, Liu Y, Wang Y, Shi C., Free PMC Article | 04/16/2022 |
| Heme Oxygenase-1 (HMOX-1) and inhibitor of differentiation proteins (ID1, ID3) are key response mechanisms against iron-overload in pancreatic beta-cells. | Heme Oxygenase-1 (HMOX-1) and inhibitor of differentiation proteins (ID1, ID3) are key response mechanisms against iron-overload in pancreatic β-cells.
Hamad M, Mohammed AK, Hachim MY, Mukhopadhy D, Khalique A, Laham A, Dhaiban S, Bajbouj K, Taneera J. | 04/2/2022 |
| EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression. | EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression.
Fang L, Gao Y, Wang Z, Li Y, Yan Y, Wu Z, Cheng JC, Sun YP., Free PMC Article | 02/26/2022 |
| Amphiregulin stimulates human chorionic gonadotropin expression by inducing ERK1/2-mediated ID3 expression in trophoblast cells. | Amphiregulin stimulates human chorionic gonadotropin expression by inducing ERK1/2-mediated ID3 expression in trophoblast cells.
Fang L, Wang S, Han X, Gao Y, Li Y, Cheng JC, Sun YP. | 02/26/2022 |
| ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition. | ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition.
Bakr A, Hey J, Sigismondo G, Liu CS, Sadik A, Goyal A, Cross A, Iyer RL, Müller P, Trauernicht M, Breuer K, Lutsik P, Opitz CA, Krijgsveld J, Weichenhan D, Plass C, Popanda O, Schmezer P., Free PMC Article | 01/1/2022 |
| LEF1/Id3/HRAS axis promotes the tumorigenesis and progression of esophageal squamous cell carcinoma. | LEF1/Id3/HRAS axis promotes the tumorigenesis and progression of esophageal squamous cell carcinoma.
Wang X, Zhao Y, Fei X, Lu Q, Li Y, Yuan Y, Lu C, Li C, Chen H., Free PMC Article | 11/22/2021 |
| Up-regulated DNA-binding inhibitor Id3 promotes differentiation of regulatory T cell to influence antiviral immunity in chronic hepatitis B virus infection. | Up-regulated DNA-binding inhibitor Id3 promotes differentiation of regulatory T cell to influence antiviral immunity in chronic hepatitis B virus infection.
Liu C, Zeng X, Yu S, Ren L, Sun X, Long Y, Wang X, Lu S, Song Y, Sun XH, Zhang Y. | 11/22/2021 |
| Correlation of the levels of DNA-binding inhibitor Id3 and regulatory T cells with SLE disease severity. | Correlation of the levels of DNA-binding inhibitor Id3 and regulatory T cells with SLE disease severity.
Liu C, Yu S, Jin R, Long Y, Lu S, Song Y, Sun X, Sun XH, Zhang Y. | 10/16/2021 |
| The HBx and HBc of hepatitis B virus can influence Id1 and Id3 by reducing their transcription and stability. | The HBx and HBc of hepatitis B virus can influence Id1 and Id3 by reducing their transcription and stability.
Xia L, Wang S, Zhang H, Yang Y, Wei J, Shi Y, Zou C, Liu J, Luo M, Huang A, Wang D. | 09/4/2021 |
| Role of inhibitor of differentiation 3 gene in cellular differentiation of human corneal stromal fibroblasts. | Role of inhibitor of differentiation 3 gene in cellular differentiation of human corneal stromal fibroblasts.
Gupta S, Martin LM, Sinha NR, Smith KE, Sinha PR, Dailey EM, Hesemann NP, Mohan RR., Free PMC Article | 08/28/2021 |
| miR-212-5p exerts tumor promoter function by regulating the Id3/PI3K/Akt axis in lung adenocarcinoma cells. | miR-212-5p exerts tumor promoter function by regulating the Id3/PI3K/Akt axis in lung adenocarcinoma cells.
Chen FF, Sun N, Wang Y, Xi HY, Yang Y, Yu BZ, Li XJ. | 03/20/2021 |
| blocks E47-mediated inhibition of beta-catenin transcription in choloangiocarcinoma cells | ID3 Promotes Stem Cell Features and Predicts Chemotherapeutic Response of Intrahepatic Cholangiocarcinoma.
Huang L, Cai J, Guo H, Gu J, Tong Y, Qiu B, Wang C, Li M, Xia L, Zhang J, Wu H, Kong X, Xia Q. | 06/20/2020 |
| our results show that the suppressive effect of TGF-beta1 on the expression of MMP1 is mediated by a transcription factor, the inhibitor of differentiation 3 (ID3) protein. Our findings provide insights into the molecular interactions and mechanisms of TGF-b1 and ID3 during the regulation of MMP1 in human granulosa-lutein cells. | ID3 mediates the TGF-β1-induced suppression of matrix metalloproteinase-1 in human granulosa cells.
Li H, Chang HM, Shi Z, Leung PCK. | 06/13/2020 |
| a critical role for highly altered Ossification of the posterior longitudinal ligament (OPLL)-specific microRNA-10a in regulating the development of OPLL by modulating the ID3/RUNX2 axis. | The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament.
Xu C, Zhang H, Gu W, Wu H, Chen Y, Zhou W, Sun B, Shen X, Zhang Z, Wang Y, Liu Y, Yuan W., Free PMC Article | 10/12/2019 |