Nanoscale Interaction of Endonuclease APE1 with DNA. | Nanoscale Interaction of Endonuclease APE1 with DNA. Vemulapalli S, Hashemi M, Chen Y, Pramanik S, Bhakat KK, Lyubchenko YL., Free PMC Article | 08/9/2024 |
Live-cell imaging of human apurinic/apyrimidinic endonuclease 1 in the nucleus and nucleolus using a chaperone@DNA probe. | Live-cell imaging of human apurinic/apyrimidinic endonuclease 1 in the nucleus and nucleolus using a chaperone@DNA probe. Cao X, Zheng J, Zhang R, Sun Y, Zhao M., Free PMC Article | 06/3/2024 |
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy. | APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy. Du Y, Zhou Y, Yan X, Pan F, He L, Guo Z, Hu Z., | 04/29/2024 |
Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer. | Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer. Mao S, Xie C, Liu Y, Zhao Y, Li M, Gao H, Xiao Y, Zou Y, Zheng Z, Gao Y, Xie J, Tian B, Wang L, Hua Y, Xu H., Free PMC Article | 03/26/2024 |
Investigation of APE1 and OGG1 expression in chronic hemodialysis patients. | Investigation of APE1 and OGG1 expression in chronic hemodialysis patients. Rostami M, Yalin SF, Altiparmak MR, Guven M. | 02/7/2024 |
In vitro and In vivo evidence demonstrating chronic absence of Ref-1 Cysteine 65 impacts Ref-1 folding configuration, redox signaling, proliferation and metastasis in pancreatic cancer. | In vitro and In vivo evidence demonstrating chronic absence of Ref-1 Cysteine 65 impacts Ref-1 folding configuration, redox signaling, proliferation and metastasis in pancreatic cancer. Mijit M, Kpenu E, Chowdhury NN, Gampala S, Wireman R, Liu S, Babb O, Georgiadis MM, Wan J, Fishel ML, Kelley MR., Free PMC Article | 02/1/2024 |
Back-Up Base Excision DNA Repair in Human Cells Deficient in the Major AP Endonuclease, APE1. | Back-Up Base Excision DNA Repair in Human Cells Deficient in the Major AP Endonuclease, APE1. Kim DV, Diatlova EA, Zharkov TD, Melentyev VS, Yudkina AV, Endutkin AV, Zharkov DO., Free PMC Article | 01/16/2024 |
Coordination between human DNA polymerase beta and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair. | Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair. Bakman AS, Boichenko SS, Kuznetsova AA, Ishchenko AA, Saparbaev M, Kuznetsov NA. | 01/3/2024 |
Expression of Apurinic/Apyrimidinic Endonuclease 1 in Colorectal Cancer and its Relation to Tumor Progression and Prognosis. | Expression of Apurinic/Apyrimidinic Endonuclease 1 in Colorectal Cancer and its Relation to Tumor Progression and Prognosis. Hong JY, Oh HH, Park SY, Park YL, Cho SB, Joo YE., Free PMC Article | 11/6/2023 |
APE1-dependent base excision repair of DNA photodimers in human cells. | APE1-dependent base excision repair of DNA photodimers in human cells. Gautam A, Fawcett H, Burdova K, Brazina J, Caldecott KW. | 10/28/2023 |
JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1. | JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1. Tabanifar B, Moorthy A, Tsai HH, Kannan S, Verma CS, Sabapathy K. | 10/11/2023 |
AUF1 Recognizes 8-Oxo-Guanosine Embedded in DNA and Stimulates APE1 Endoribonuclease Activity. | AUF1 Recognizes 8-Oxo-Guanosine Embedded in DNA and Stimulates APE1 Endoribonuclease Activity. Malfatti MC, Codrich M, Dalla E, D'Ambrosio C, Storici F, Scaloni A, Tell G., Free PMC Article | 09/19/2023 |
APE1 promotes embryonic stem cell proliferation and teratoma formation by regulating GDNF/GFRalpha1 axis. | APE1 promotes embryonic stem cell proliferation and teratoma formation by regulating GDNF/GFRα1 axis. Liu L, Wu Q, Wang Z, Niu B, Jiao Y, An H. | 08/30/2023 |
Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons. | Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons. Malfatti MC, Bellina A, Antoniali G, Tell G., Free PMC Article | 08/2/2023 |
Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics. | Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics. Hoitsma NM, Norris J, Khoang TH, Kaushik V, Chadda R, Antony E, Hedglin M, Freudenthal BD., Free PMC Article | 07/26/2023 |
Elevated APE1 Dysregulates Homologous Recombination and Cell Cycle Driving Genomic Evolution, Tumorigenesis, and Chemoresistance in Esophageal Adenocarcinoma. | Elevated APE1 Dysregulates Homologous Recombination and Cell Cycle Driving Genomic Evolution, Tumorigenesis, and Chemoresistance in Esophageal Adenocarcinoma. Kumar S, Zhao J, Talluri S, Buon L, Mu S, Potluri LB, Liao C, Shi J, Chakraborty C, Gonzalez GB, Tai YT, Patel J, Pal J, Mashimo H, Samur MK, Munshi NC, Shammas MA., Free PMC Article | 07/25/2023 |
Fluorescently labeled human apurinic/apyrimidinic endonuclease APE1 reveals effects of DNA polymerase beta on the APE1-DNA interaction. | Fluorescently labeled human apurinic/apyrimidinic endonuclease APE1 reveals effects of DNA polymerase β on the APE1-DNA interaction. Bakman AS, Kuznetsova AA, Yanshole LV, Ishchenko AA, Saparbaev M, Fedorova OS, Kuznetsov NA. | 03/4/2023 |
Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-kappaB activation in oesophageal adenocarcinoma. | Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma. Chen L, Lu H, Peng D, Cao LL, Ballout F, Srirmajayam K, Chen Z, Bhat A, Wang TC, Capobianco A, Que J, McDonald OG, Zaika A, Zhang S, El-Rifai W., Free PMC Article | 02/16/2023 |
APEX1 promotes the oncogenicity of hepatocellular carcinoma via regulation of MAP2K6. | APEX1 promotes the oncogenicity of hepatocellular carcinoma via regulation of MAP2K6. Sun Z, Chen G, Wang L, Sang Q, Xu G, Zhang N., Free PMC Article | 10/29/2022 |
APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett's-associated esophageal adenocarcinomas. | APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett's-associated esophageal adenocarcinomas. Ballout F, Lu H, Chen L, Sriramajayam K, Que J, Meng Z, Wang TC, Giordano S, Zaika A, McDonald O, Peng D, El-Rifai W., Free PMC Article | 09/10/2022 |
Dual Function of Secreted APE1/Ref-1 in TNBC Tumorigenesis: An Apoptotic Initiator and a Regulator of Chronic Inflammatory Signaling. | Dual Function of Secreted APE1/Ref-1 in TNBC Tumorigenesis: An Apoptotic Initiator and a Regulator of Chronic Inflammatory Signaling. Choi S, Lee YR, Kim KM, Choi E, Jeon BH., Free PMC Article | 09/3/2022 |
Gliadin induced oxidative stress and altered cellular responses in human intestinal cells: An in-vitro study to understand the cross-talk between the transcription factor Nrf-2 and multifunctional APE1 enzyme. | Gliadin induced oxidative stress and altered cellular responses in human intestinal cells: An in-vitro study to understand the cross-talk between the transcription factor Nrf-2 and multifunctional APE1 enzyme. Gupta KB, Dhiman M, Mantha AK. | 08/20/2022 |
Conformational Rearrangements Regulating the DNA Repair Protein APE1. | Conformational Rearrangements Regulating the DNA Repair Protein APE1. Komaniecka N, Porras M, Cairn L, Santas JA, Ferreiro N, Penedo JC, Bañuelos S., Free PMC Article | 08/6/2022 |
Idiopathic sudden sensorineural hearing loss: A critique on corticosteroid therapy. | Idiopathic sudden sensorineural hearing loss: A critique on corticosteroid therapy. Murray DH, Fagan PA, Ryugo DK. | 08/6/2022 |
APEX1 regulates alternative splicing of key tumorigenesis genes in non-small-cell lung cancer. | APEX1 regulates alternative splicing of key tumorigenesis genes in non-small-cell lung cancer. Peng L, Liu Y, Chen J, Cheng M, Wu Y, Chen M, Zhong Y, Shen D, Chen L, Ye X., Free PMC Article | 07/16/2022 |