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    PRMT1 protein arginine methyltransferase 1 [ Homo sapiens (human) ]

    Gene ID: 3276, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    P4HB regulates the TGFbeta/SMAD3 signaling pathway through PRMT1 to participate in high glucose-induced epithelial-mesenchymal transition and fibrosis of renal tubular epithelial cells.

    P4HB regulates the TGFβ/SMAD3 signaling pathway through PRMT1 to participate in high glucose-induced epithelial-mesenchymal transition and fibrosis of renal tubular epithelial cells.
    Wang H, Li Y, Wu N, Lv C, Wang Y., Free PMC Article

    10/31/2024
    PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma.

    PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma.
    Walton J, Ng ASN, Arevalo K, Apostoli A, Meens J, Karamboulas C, St-Germain J, Prinos P, Dmytryshyn J, Chen E, Arrowsmith CH, Raught B, Ailles L., Free PMC Article

    09/25/2024
    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer.

    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer.
    Nguyen CDK, Colón-Emeric BA, Murakami S, Shujath MNY, Yi C., Free PMC Article

    09/24/2024
    PRMT1 mediates the proliferation of Y79 retinoblastoma cells by regulating the p53/p21/CDC2/cyclin B pathway.

    PRMT1 mediates the proliferation of Y79 retinoblastoma cells by regulating the p53/p21/CDC2/cyclin B pathway.
    Zhang Y, Mao L, Jiang A, Liu J, Lu Y, Yao C, Huang G.

    09/19/2024
    Arginine Methylation of DDX3 by PRMT1 Mediates Mitochondrial Homeostasis to Promote Breast Cancer Metastasis.

    Arginine Methylation of DDX3 by PRMT1 Mediates Mitochondrial Homeostasis to Promote Breast Cancer Metastasis.
    Hsu WJ, Chiang MC, Chao YC, Chang YC, Hsu MC, Chung CH, Tsai IL, Chu CY, Wu HC, Yang CC, Lee CC, Lin CW.

    09/17/2024
    PRMT1 and TDRD3 promote stress granule assembly by rebuilding the protein-RNA interaction network.

    PRMT1 and TDRD3 promote stress granule assembly by rebuilding the protein-RNA interaction network.
    Qin M, Fan W, Li L, Xu T, Zhang H, Chen F, Man J, Kombe AJK, Zhang J, Shi Y, Yao X, Yang Z, Hou Z, Ruan K, Liu D.

    09/12/2024
    Caprin1 Bridges PRMT1 to G3BP1 and Spaces Them to Ensure Proper Stress Granule Formation.

    Caprin1 Bridges PRMT1 to G3BP1 and Spaces Them to Ensure Proper Stress Granule Formation.
    Qin M, Fan W, Chen F, Ruan K, Liu D.

    09/9/2024
    Tumor Necrosis Factor alpha-Induced Protein 8-Like 1 Binds to Protein Arginine Methyltransferase 1 to Suppress the Methylation of Signal Transducer and Activator of Transcription 3 and Cell Growth in Oral Squamous Cell Carcinoma.

    Tumor Necrosis Factor α-Induced Protein 8-Like 1 Binds to Protein Arginine Methyltransferase 1 to Suppress the Methylation of Signal Transducer and Activator of Transcription 3 and Cell Growth in Oral Squamous Cell Carcinoma.
    Liu B, Si W, Wei B, Zhang X, Chen P.

    08/7/2024
    EGR3 reduces podocyte inflammatory damage in obesity related glomerulopathy by inhibiting the PRMT1/p-STAT3 pathway.

    EGR3 reduces podocyte inflammatory damage in obesity related glomerulopathy by inhibiting the PRMT1/p-STAT3 pathway.
    Peng L, Sun X, Yi X, Wang Z, Chen K., Free PMC Article

    08/1/2024
    Oligomerization of protein arginine methyltransferase 1 and its effect on methyltransferase activity and substrate specificity.

    Oligomerization of protein arginine methyltransferase 1 and its effect on methyltransferase activity and substrate specificity.
    Rossi V, Nielson SE, Ortolano A, Lonardo I, Haroldsen E, Comer D, Price OM, Wallace N, Hevel JM., Free PMC Article

    07/19/2024
    FBXO7 ubiquitinates PRMT1 to suppress serine synthesis and tumor growth in hepatocellular carcinoma.

    FBXO7 ubiquitinates PRMT1 to suppress serine synthesis and tumor growth in hepatocellular carcinoma.
    Luo L, Wu X, Fan J, Dong L, Wang M, Zeng Y, Li S, Yang W, Jiang J, Wang K., Free PMC Article

    06/13/2024
    LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis.

    LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis.
    Cao N, Zhang F, Yin J, Zhang J, Bian X, Zheng G, Li N, Lin Y, Luo L., Free PMC Article

    06/6/2024
    PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer.

    PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer.
    Yamamoto T, Hayashida T, Masugi Y, Oshikawa K, Hayakawa N, Itoh M, Nishime C, Suzuki M, Nagayama A, Kawai Y, Hishiki T, Matsuura T, Naito Y, Kubo A, Yamamoto A, Yoshioka Y, Kurahori T, Nagasaka M, Takizawa M, Takano N, Kawakami K, Sakamoto M, Wakui M, Yamamoto T, Kitagawa Y, Kabe Y, Horisawa K, Suzuki A, Matsumoto M, Suematsu M., Free PMC Article

    04/5/2024
    PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity.

    PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity.
    Djajawi TM, Pijpers L, Srivaths A, Chisanga D, Chan KF, Hogg SJ, Neil L, Rivera SM, Bartonicek N, Ellis SL, Lim Kam Sian TCC, Faridi P, Liao Y, Pal B, Behren A, Shi W, Vervoort SJ, Johnstone RW, Kearney CJ.

    04/1/2024
    PRMT1 promotes pancreatic cancer development and resistance to chemotherapy.

    PRMT1 promotes pancreatic cancer development and resistance to chemotherapy.
    Ku B, Eisenbarth D, Baek S, Jeong TK, Kang JG, Hwang D, Noh MG, Choi C, Choi S, Seol T, Kim H, Kim YH, Woo SM, Kong SY, Lim DS., Free PMC Article

    03/22/2024
    Inhibition of PRMT1 Suppresses the Growth of U87MG-Derived Glioblastoma Stem Cells by Blocking the STAT3 Signaling Pathway.

    Inhibition of PRMT1 Suppresses the Growth of U87MG-Derived Glioblastoma Stem Cells by Blocking the STAT3 Signaling Pathway.
    Yuk N, Jung HJ., Free PMC Article

    03/20/2024
    PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis.

    PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis.
    Liu H, Chen X, Wang P, Chen M, Deng C, Qian X, Bai J, Li Z, Yu X., Free PMC Article

    02/26/2024
    Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1.

    Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1.
    Rowley MJ, Prout-Holm RA, Liu RW, Hendrickson-Rebizant T, Ige OO, Lakowski TM, Frankel A., Free PMC Article

    01/9/2024
    Targeting PRMT1 prevents acute and chronic graft-versus-host disease.

    Targeting PRMT1 prevents acute and chronic graft-versus-host disease.
    Zhao X, Sun Y, Xu Z, Cai L, Hu Y, Wang H., Free PMC Article

    11/27/2023
    PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.

    PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.
    Feng G, Chen C, Luo Y., Free PMC Article

    11/13/2023
    CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth.

    CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth.
    Yin S, Liu L, Ball LE, Wang Y, Bedford MT, Duncan SA, Wang H, Gan W., Free PMC Article

    10/6/2023
    Methylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion.

    Methylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion.
    Liu Y, Liu H, Ye M, Jiang M, Chen X, Song G, Ji H, Wang ZW, Zhu X., Free PMC Article

    09/28/2023
    Metabolome Sequencing Reveals that Protein Arginine-N-Methyltransferase 1 Promotes the Progression of Invasive Micropapillary Carcinoma of the Breast and Predicts a Poor Prognosis.

    Metabolome Sequencing Reveals that Protein Arginine-N-Methyltransferase 1 Promotes the Progression of Invasive Micropapillary Carcinoma of the Breast and Predicts a Poor Prognosis.
    Wu K, Li W, Liu H, Niu C, Shi Q, Zhang J, Gao G, Sun H, Liu F, Fu L.

    08/28/2023
    Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma.

    Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma.
    Nguyen HP, Le AQ, Liu E, Cesarano A, DiMeo F, Perna F, Kapur R, Walker BA, Tran NT., Free PMC Article

    08/22/2023
    Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis.

    Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis.
    Kim E, Rahmawati L, Aziz N, Kim HG, Kim JH, Kim KH, Yoo BC, Parameswaran N, Kang JS, Hur H, Manavalan B, Lee J, Cho JY., Free PMC Article

    08/16/2023
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