APC and ZBTB2 May Mediate M2 Macrophage Infiltration to Promote the Development of Renal Fibrosis: A Bioinformatics Analysis. | APC and ZBTB2 May Mediate M2 Macrophage Infiltration to Promote the Development of Renal Fibrosis: A Bioinformatics Analysis. Song J, Ke B, Fang X., Free PMC Article | 10/7/2024 |
Plasma-Derived Extracellular Vesicles and Non-Extracellular Vesicle Components from APC[Min/+] Mice Promote Pro-Tumorigenic Activities and Activate Human Colonic Fibroblasts via the NF-kappaB Signaling Pathway. | Plasma-Derived Extracellular Vesicles and Non-Extracellular Vesicle Components from APC(Min/+) Mice Promote Pro-Tumorigenic Activities and Activate Human Colonic Fibroblasts via the NF-κB Signaling Pathway. Arteaga-Blanco LA, Evans AE, Dixon DA., Free PMC Article | 08/1/2024 |
Bcl-2 Up-Regulation Mediates Taxane Resistance Downstream of APC Loss. | Bcl-2 Up-Regulation Mediates Taxane Resistance Downstream of APC Loss. Wise AR, Maloney S, Hering A, Zabala S, Richmond GE, VanKlompenberg MK, Nair MT, Prosperi JR., Free PMC Article | 07/5/2024 |
Mutational analysis of pulmonary large cell neuroendocrine carcinoma: APC gene mutations identify a good prognostic factor. | Mutational analysis of pulmonary large cell neuroendocrine carcinoma: APC gene mutations identify a good prognostic factor. Li M, Zhang Y, Zhou P, Miao Y, Li S, Jiang L. | 06/13/2024 |
BET protein-dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer. | BET protein-dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer. Morino S, Mashima T, Shirai F, Nagayama S, Katayama R, Seimiya H. | 02/28/2024 |
beta-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53. | β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53. Bourmoum M, Radulovich N, Sharma A, Tkach JM, Tsao MS, Pelletier L., Free PMC Article | 02/20/2024 |
Case Series of Men with the Germline APC I1307K variant and Treatment-Emergent Neuroendocrine Prostate Cancer. | Case Series of Men with the Germline APC I1307K variant and Treatment-Emergent Neuroendocrine Prostate Cancer. Economides MP, Nakazawa M, Lee JW, Li X, Hollifield L, Chambers R, Sarfaty M, Goldberg JD, Antonarakis ES, Wise DR. | 02/16/2024 |
Clinical features and distribution of the APC variant in duodenal and ampullary polyps in patients with familial adenomatous polyposis: a multicenter retrospective cohort study in Japan. | Clinical features and distribution of the APC variant in duodenal and ampullary polyps in patients with familial adenomatous polyposis: a multicenter retrospective cohort study in Japan. Miyakura Y, Yamaguchi T, Lefor AK, Tamaki S, Takao A, Takao M, Mori Y, Chikatani K, Ishida H, Kono M, Takeuchi Y, Ishikawa H, Nagasaki T, Sasaki K, Matsubara T, Hirata K, Taniguchi F, Tanakaya K, Tomita N, Ajioka Y. | 02/5/2024 |
A novel APC mutation associated with Gardner syndrome in a Chinese family. | A novel APC mutation associated with Gardner syndrome in a Chinese family. Zeng M, Yao X, Pan Y, Gu H, Xiong F, Yin X, Wu B, Chen T. | 02/1/2024 |
APC mutations disrupt beta-catenin destruction complex condensates organized by Axin phase separation. | APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation. Zhang D, Ni QQ, Wang SY, He WF, Hong ZX, Liu HY, Chen XH, Chen LJ, Han FY, Zhang LJ, Li XM, Ding YQ, Jiao HL, Ye YP., Free PMC Article | 01/30/2024 |
APC/PIK3CA mutations and beta-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells. | APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells. Chen M, Mashima T, Oishi T, Muramatsu Y, Seto Y, Takamatsu M, Kawata N, Morino S, Nakamura A, Inaba S, Yuan X, Maruyama K, Suzuki M, Sato A, Yoshida H, Jang MK, Mizutani A, Takeuchi K, Yamaguchi K, Shirai F, Nagayama S, Katayama R, Seimiya H., Free PMC Article | 01/12/2024 |
A one-stop approach to diagnosing hereditary colorectal cancer in the Chinese population. | A one-stop approach to diagnosing hereditary colorectal cancer in the Chinese population. Li C, Song W, Xu Y, Guo T, Zhou X, Liu F, Xu Y. | 01/4/2024 |
Low adenoma burden in unselected patients with a pathogenic APC variant. | Low adenoma burden in unselected patients with a pathogenic APC variant. Schwiter R, Rocha H, Johns A, Savatt JM, Diehl DL, Kelly MA, Williams MS, Buchanan AH. | 12/20/2023 |
An update of the variant spectrum of the APC gene in Iranian familial adenomatous polyposis patients. | An update of the variant spectrum of the APC gene in Iranian familial adenomatous polyposis patients. Mirabdolhosseini SM, Rejali L, Yaghoob Taleghani M, Sadeghi H, Kashfi SMH, Behboudi Farahbakhsh F, Golmohammadi M, Larki P, Fatemi N, Ketabi Moghadam P, Nazemalhosseini Mojarad E, Sadeghi A, Asadzadeh Aghdaie H, Zali MR. | 12/15/2023 |
Usefulness of genotyping APC gene for individualizing management of patients with familial adenomatous polyposis. | Usefulness of genotyping APC gene for individualizing management of patients with familial adenomatous polyposis. Mori Y, Ishida H, Chika N, Ito T, Amano K, Chikatani K, Takeuchi Y, Kono M, Shichijo S, Chino A, Nagasaki T, Takao A, Takao M, Nakamori S, Sasaki K, Akagi K, Yamaguchi T, Tanakaya K, Naohiro T, Ajioka Y. | 12/4/2023 |
Germline APC Alterations May Predispose to Testicular Sex Cord-Stromal Tumors. | Germline APC Alterations May Predispose to Testicular Sex Cord-Stromal Tumors. Siegmund S, Ricci C, Kao CS, Sangoi AR, Mohanty S, Fletcher CDM, Colecchia M, Acosta AM. | 11/18/2023 |
CTNNB1 and APC Mutations in Sinonasal Myxoma : Expanding the Spectrum of Tumors Driven By WNT/beta-catenin Pathway. | CTNNB1 and APC Mutations in Sinonasal Myxoma : Expanding the Spectrum of Tumors Driven By WNT/β-catenin Pathway. Chen S, Gallant S, Cunningham MJ, Robson CD, Church AJ, Perez-Atayde AR, Al-Ibraheemi A. | 10/30/2023 |
Clinical significance of SPOP and APC gene alterations in colorectal cancer in Indian population. | Clinical significance of SPOP and APC gene alterations in colorectal cancer in Indian population. Ali A, Nimisha, Sharma AK, Mishra PK, Saluja SS. | 07/25/2023 |
Long noncoding RNA UFC1 acts as an oncogene via stimulating EZH2-induced inhibition of APC expression in renal cell carcinoma. | Long noncoding RNA UFC1 acts as an oncogene via stimulating EZH2-induced inhibition of APC expression in renal cell carcinoma. Wang J, Liu G. | 06/28/2023 |
The adenomatous polyposis coli protein 30 years on. | The adenomatous polyposis coli protein 30 years on. Abbott J, Näthke IS. | 06/5/2023 |
Let-7b-5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1. | Let-7b-5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1. Dai Y, Liu J, Li X, Deng J, Zeng C, Lu W, Hou Y, Sheng Y, Wu H, Liu Q., Free PMC Article | 05/7/2023 |
APC germline pathogenic variants and epithelial ovarian cancer: causal or coincidental findings? | APC germline pathogenic variants and epithelial ovarian cancer: causal or coincidental findings? Vibert R, Le Gall J, Buecher B, Mouret-Fourme E, Bataillon G, Becette V, Trabelsi-Grati O, Moncoutier V, Dehainault C, Carriere J, Schwartz M, Suybeng V, Bieche I, Colas C, Vincent-Salomon A, Stoppa-Lyonnet D, Golmard L. | 04/26/2023 |
Rare Genetic Variants in Human APC Are Implicated in Mesiodens and Isolated Supernumerary Teeth. | Rare Genetic Variants in Human APC Are Implicated in Mesiodens and Isolated Supernumerary Teeth. Panyarat C, Nakornchai S, Chintakanon K, Leelaadisorn N, Intachai W, Olsen B, Tongsima S, Adisornkanj P, Ngamphiw C, Cox TC, Kantaputra P., Free PMC Article | 03/15/2023 |
Impact of a haplotype (composed of the APC, KRAS, and TP53 genes) on colorectal adenocarcinoma differentiation and patient prognosis. | Impact of a haplotype (composed of the APC, KRAS, and TP53 genes) on colorectal adenocarcinoma differentiation and patient prognosis. Peng X, Zhang T, Jia X, Wang T, Lin H, Li G, Li R, Zhang A. | 12/3/2022 |
Constitutional chromothripsis of the APC locus as a cause of genetic predisposition to colon cancer. | Constitutional chromothripsis of the APC locus as a cause of genetic predisposition to colon cancer. Scharf F, Leal Silva RM, Morak M, Hastie A, Pickl JMA, Sendelbach K, Gebhard C, Locher M, Laner A, Steinke-Lange V, Koehler U, Holinski-Feder E, Wolf DA., Free PMC Article | 10/29/2022 |