| Tumor-mesothelium HOXA11-PDGF BB/TGF beta1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer. | Tumor-mesothelium HOXA11-PDGF BB/TGF β1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer.
Wang C, Ji J, Jin Y, Sun Y, Cai Q, Jiang J, Guo L, Zhou C, Zhang J., Free PMC Article | 01/27/2024 |
| Endometrial Injury Upregulates Expression of Receptivity Genes in Women with Implantation Failure. | Endometrial Injury Upregulates Expression of Receptivity Genes in Women with Implantation Failure.
Celik O, Yurci A, Ersahin A, Gungor ND, Celik N, Ozcil MD, Dogan S, Dalkilic S, Dalkilic L, Ulug U, Celik S, Tinelli A., Free PMC Article | 10/28/2023 |
| Cooperation between NSPc1 and DNA methylation represses HOXA11 expression and promotes apoptosis of trophoblast cells during preeclampsia. | Cooperation between NSPc1 and DNA methylation represses HOXA11 expression and promotes apoptosis of trophoblast cells during preeclampsia.
Xie L, Ding N, Sheng S, Zhang H, Yin H, Gao L, Zhang H, Ma S, Yang A, Li G, Jiao Y, Shi Q, Jiang Y, Zhang H., Free PMC Article | 05/8/2023 |
| lncRNA HOXA11-AS maintains the stemness of oral squamous cell carcinoma stem cells and reduces the radiosensitivity by targeting miR-518a-3p/PDK1. | lncRNA HOXA11-AS maintains the stemness of oral squamous cell carcinoma stem cells and reduces the radiosensitivity by targeting miR-518a-3p/PDK1.
Li B, Lv Y, Zhang C, Xiang C. | 03/21/2023 |
| The lncRNA HOXA11-AS acts as a tumor promoter in breast cancer through regulation of the miR-125a-5p/TMPRSS4 axis. | The lncRNA HOXA11-AS acts as a tumor promoter in breast cancer through regulation of the miR-125a-5p/TMPRSS4 axis.
Xu Y, Ren Z, Wang X, Ren M. | 05/14/2022 |
| Decreased expression of transcription factor Homeobox A11 and its potential target genes in bladder cancer. | Decreased expression of transcription factor Homeobox A11 and its potential target genes in bladder cancer.
Wang SS, Zhai GQ, Chen G, Huang ZG, He RQ, Huang SN, Liu JL, Cheng JW, Yan HB, Dang YW, Li SH. | 05/7/2022 |
| Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors. | Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors.
Bergman-Larsson J, Gustafsson S, Méar L, Huvila J, Tolf A, Olovsson M, Pontén F, Edqvist PD. | 03/26/2022 |
| HOXA11 plays critical roles in disease progression and response to cytarabine in AML. | HOXA11 plays critical roles in disease progression and response to cytarabine in AML.
Fu JF, Shih LY, Yen TH., Free PMC Article | 12/4/2021 |
| Long noncoding RNA HOXA11AS accelerates cell proliferation and epithelialmesenchymal transition in hepatocellular carcinoma by modulating the miR5063p/Slug axis. | Long non‑coding RNA HOXA11‑AS accelerates cell proliferation and epithelial‑mesenchymal transition in hepatocellular carcinoma by modulating the miR‑506‑3p/Slug axis.
Liu Y, Yan W, Zhou D, Jin G, Cheng X., Free PMC Article | 07/3/2021 |
| A homozygous HOXA11 variation as a potential novel cause of autosomal recessive congenital anomalies of the kidney and urinary tract. | A homozygous HOXA11 variation as a potential novel cause of autosomal recessive congenital anomalies of the kidney and urinary tract.
Saygili S, Atayar E, Canpolat N, Elicevik M, Kurugoglu S, Sever L, Caliskan S, Ozaltin F. | 07/3/2021 |
| Molecular mechanism of extracellular matrix disorder in pelvic organ prolapses. | Molecular mechanism of extracellular matrix disorder in pelvic organ prolapses.
Zhang L, Dai F, Chen G, Wang Y, Liu S, Zhang L, Xian S, Yuan M, Yang D, Zheng Y, Deng Z, Cheng Y, Yang X., Free PMC Article | 05/15/2021 |
| Laparoscopic Ovarian Drilling Improves Endometrial Homeobox Gene Expression in PCOS. | Laparoscopic Ovarian Drilling Improves Endometrial Homeobox Gene Expression in PCOS.
Senturk S, Celik O, Dalkilic S, Hatirnaz S, Celik N, Unlu C, Otlu B. | 12/12/2020 |
| Correlation of miR-181a and three HOXA genes as useful biomarkers in acute myeloid leukemia. | Correlation of miR-181a and three HOXA genes as useful biomarkers in acute myeloid leukemia.
Xu P, Zhou D, Yan G, Ouyang J, Chen B. | 10/3/2020 |
| A self-enforcing HOXA11/Stat3 feedback loop promotes stemness properties and peritoneal metastasis in gastric cancer cells. | A self-enforcing HOXA11/Stat3 feedback loop promotes stemness properties and peritoneal metastasis in gastric cancer cells.
Wang C, Shi M, Ji J, Cai Q, Jiang J, Zhang H, Zhu Z, Zhang J., Free PMC Article | 09/12/2020 |
| Study suggested that HOXA11-AS silencing exerts an antitumor effect, suppressing HCC development via Wnt signaling pathway inactivation by decreasing the methylation level of the HOXA11 promoter. | Silencing of long noncoding RNA HOXA11-AS inhibits the Wnt signaling pathway via the upregulation of HOXA11 and thereby inhibits the proliferation, invasion, and self-renewal of hepatocellular carcinoma stem cells.
Guo JC, Yang YJ, Zheng JF, Zhang JQ, Guo M, Yang X, Jiang XL, Xiang L, Li Y, Ping H, Zhuo L., Free PMC Article | 06/20/2020 |
| Study found that HOXA11 is hypermethylated and significantly downregulated in cisplatin resistant lung adenocarcinoma tumors and cell lines and that the 5-aza-CdR treatment restores HOXA11 expression and reverses the hypermethylation of CpG islands. | An inverse interaction between HOXA11 and HOXA11-AS is associated with cisplatin resistance in lung adenocarcinoma.
Zhang Y, Yuan Y, Li Y, Zhang P, Chen P, Sun S., Free PMC Article | 05/30/2020 |
| HOXA11-AS induced collagen synthesis via sponging miR-124-3p-mediated Smad5 signaling in keloid cells. | Long non-coding RNA HOXA11-AS induces type I collagen synthesis to stimulate keloid formation via sponging miR-124-3p and activation of Smad5 signaling.
Jin J, Zhai HF, Jia ZH, Luo XH. | 04/11/2020 |
| Abnormal methylation levels of the HOXA10 and HOXA11 promoters were found in the endometrium of women with tubal infertility and repeated implantation failures. | The role of abnormal hypermethylation of the HOXA10 and HOXA11 promoters in implantation failures in IVF programs.
Nazarenko TA, Kalinina EA, Knyazeva EA, Kiselev VI, Smolnikova VY, Sukhikh GT. | 03/7/2020 |
| HOXA11-AS could inhibit miR-124 expression by binding to EZH2 and thus promoted the migration and invasion of HCC cells. | HOXA11-AS promotes the migration and invasion of hepatocellular carcinoma cells by inhibiting miR-124 expression by binding to EZH2.
Zhang WL, Zhao YN, Shi ZZ, Gu GY, Cong D, Wei C, Bai YS. | 02/29/2020 |
| HOXA11-AS regulates diabetic arteriosclerosis-related inflammation via PI3K/AKT pathway | HOXA11-AS regulates diabetic arteriosclerosis-related inflammation via PI3K/AKT pathway.
Jin QS, Huang LJ, Zhao TT, Yao XY, Lin LY, Teng YQ, Kim SH, Nam MS, Zhang LY, Jin YJ. | 11/23/2019 |
| HOXA11 high expression might lead to the occurrence and development of lung squamous cancer. | Evaluation of the HOXA11 level in patients with lung squamous cancer and insights into potential molecular pathways via bioinformatics analysis.
Zhang R, Zhang TT, Zhai GQ, Guo XY, Qin Y, Gan TQ, Zhang Y, Chen G, Mo WJ, Feng ZB., Free PMC Article | 04/20/2019 |
| we uncovered a novel potential regulatory mechanism between HOTTIP and one of its physical HOXA clusters, HOXA11. Hence, HOTTIP may mediate, at least partly, HOXA11 expression involved in cell growth, migration, and apoptosis of breast cancer MCF-7 cells. | LncRNA HOTTIP-Mediated HOXA11 Expression Promotes Cell Growth, Migration and Inhibits Cell Apoptosis in Breast Cancer.
Sun Y, Zeng C, Gan S, Li H, Cheng Y, Chen D, Li R, Zhu W., Free PMC Article | 08/11/2018 |
| We conclude that the expression patterns of HoxA10, HoxA11, and HoxA13 and their actions in regulating CAP genes in the uterus create regionalized myometrium phenotypes in women that may be important to control regionalized myometrium contractility for maintaining pregnancy. | HoxA10 and HoxA11 Regulate the Expression of Contraction-Associated Proteins and Contribute to Regionalized Myometrium Phenotypes in Women.
Li Y, Li H, Xie N, Chen R, Lee AR, Slater D, Lye S, Dong X. | 07/28/2018 |
| High expression of lncRNA HOXA11-AS promotes breast cancer invasion and metastasis by affecting EMT. | Long Non-Coding RNA (LncRNA) HOXA11-AS Promotes Breast Cancer Invasion and Metastasis by Regulating Epithelial-Mesenchymal Transition.
Li W, Jia G, Qu Y, Du Q, Liu B, Liu B., Free PMC Article | 04/28/2018 |
| HOXA11 silencing suppressed osteosarcoma cell proliferation, invasion and induced cell arrest. | Long non-coding RNA HOXA11-AS functions as a competing endogenous RNA to regulate ROCK1 expression by sponging miR-124-3p in osteosarcoma.
Cui M, Wang J, Li Q, Zhang J, Jia J, Zhan X. | 04/7/2018 |