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    HNRNPK heterogeneous nuclear ribonucleoprotein K [ Homo sapiens (human) ]

    Gene ID: 3190, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Hnrnpk protects against osteoarthritis through targeting WWC1 mRNA and inhibiting Hippo signaling pathway.

    Hnrnpk protects against osteoarthritis through targeting WWC1 mRNA and inhibiting Hippo signaling pathway.
    Zhang S, Zhang B, Liao Z, Chen Y, Guo W, Wu J, Liu H, Weng R, Su D, Chen G, Zhang Z, Li C, Long J, Xiao Y, Ma Y, Zhou T, Xu C, Su P.,

    05/23/2024
    Tumor-suppressive miR-4732-3p is sorted into fucosylated exosome by hnRNPK to avoid the inhibition of lung cancer progression.

    Tumor-suppressive miR-4732-3p is sorted into fucosylated exosome by hnRNPK to avoid the inhibition of lung cancer progression.
    Zhuang W, Liu C, Hong Y, Zheng Y, Huang M, Tang H, Zhao L, Huang Z, Tu M, Yu L, Chen J, Zhang Y, Chen X, Lin F, Gao Q, Yu C, Huang Y., Free PMC Article

    05/13/2024
    Heterogeneous nuclear ribonucleoprotein K promotes cap-independent translation initiation of retroviral mRNAs.

    Heterogeneous nuclear ribonucleoprotein K promotes cap-independent translation initiation of retroviral mRNAs.
    Fuentes Y, Olguín V, López-Ulloa B, Mendonça D, Ramos H, Abdalla AL, Guajardo-Contreras G, Niu M, Rojas-Araya B, Mouland AJ, López-Lastra M., Free PMC Article

    03/25/2024
    Regulatory mechanism of interaction between Y-box-binding protein 1 and heterogenous nuclear ribonucleoprotein K in cell division cycle 25a signal pathway and lung cancer metastasis.

    Regulatory mechanism of interaction between Y-box-binding protein 1 and heterogenous nuclear ribonucleoprotein K in cell division cycle 25a signal pathway and lung cancer metastasis.
    Fu L, Yang M, Ma Y.

    02/1/2024
    HnRNP K regulates inflammatory gene expression by mediating splicing pattern of transcriptional factors.

    HnRNP K regulates inflammatory gene expression by mediating splicing pattern of transcriptional factors.
    Liu S, Duan Y, You R, Chen D, Tan J., Free PMC Article

    11/28/2023
    c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis.

    c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis.
    Li B, Yao B, Guo X, Wang Z, Xie W, Wu X, Wang F, Mei Y.

    09/20/2023
    Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer.

    Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer.
    Fallatah A, Anastasakis DG, Manzourolajdad A, Sharma P, Wang X, Jacob A, Alsharif S, Elgerbi A, Coulombe PA, Hafner M, Chung BM., Free PMC Article

    08/22/2023
    hnRNP K induces HPV16 oncogene expression and promotes cervical cancerization.

    hnRNP K induces HPV16 oncogene expression and promotes cervical cancerization.
    Lyu Y, Song L, Mao R, Liu C, Feng M, Wu C, Pei R, Ding L, Wang J.

    07/27/2023
    MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.

    MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.
    Chu F, Wu P, Mu M, Hu S, Niu C., Free PMC Article

    07/20/2023
    Unravelling the Tripartite Interactions Among Hepatitis E Virus RNA, miR-140 and hnRNP K.

    Unravelling the Tripartite Interactions Among Hepatitis E Virus RNA, miR-140 and hnRNP K.
    Patil R, Salunke P, Karpe YA.

    05/25/2023
    Epigenetic Control of Cancer Cell Proliferation and Cell Cycle Progression by HNRNPK via Promoting Exon 4 Inclusion of Histone Code Reader SPIN1.

    Epigenetic Control of Cancer Cell Proliferation and Cell Cycle Progression by HNRNPK via Promoting Exon 4 Inclusion of Histone Code Reader SPIN1.
    Li D, Guo J, Jia R.

    04/4/2023
    BBOX1-AS1 mediates trophoblast cells dysfunction via regulating hnRNPK/GADD45A axisdagger.

    BBOX1-AS1 mediates trophoblast cells dysfunction via regulating hnRNPK/GADD45A axis†.
    Li Y, Zhao H, Li N, Yuan C, Dong N, Wen J, Li Z, Wang Q, Wang L, Mao H.

    03/17/2023
    The SYNGAP1 3'UTR Variant in ALS Patients Causes Aberrant SYNGAP1 Splicing and Dendritic Spine Loss by Recruiting HNRNPK.

    The SYNGAP1 3'UTR Variant in ALS Patients Causes Aberrant SYNGAP1 Splicing and Dendritic Spine Loss by Recruiting HNRNPK.
    Yokoi S, Ito T, Sahashi K, Nakatochi M, Nakamura R, Tohnai G, Fujioka Y, Ishigaki S, Udagawa T, Izumi Y, Morita M, Kano O, Oda M, Sone T, Okano H, Atsuta N, Katsuno M, Okada Y, Sobue G., Free PMC Article

    12/3/2022
    Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation.

    Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation.
    Mucha B, Qie S, Bajpai S, Tarallo V, Diehl JN, Tedeschi F, Zhou G, Gao Z, Flashner S, Klein-Szanto AJ, Hibshoosh H, Masataka S, Chajewski OS, Majsterek I, Pytel D, Hatzoglou M, Der CJ, Nakagawa H, Bass AJ, Wong KK, Fuchs SY, Rustgi AK, Jankowsky E, Diehl JA., Free PMC Article

    11/12/2022
    An HNRNPK-specific DNA methylation signature makes sense of missense variants and expands the phenotypic spectrum of Au-Kline syndrome.

    An HNRNPK-specific DNA methylation signature makes sense of missense variants and expands the phenotypic spectrum of Au-Kline syndrome.
    Choufani S, McNiven V, Cytrynbaum C, Jangjoo M, Adam MP, Bjornsson HT, Harris J, Dyment DA, Graham GE, Nezarati MM, Aul RB, Castiglioni C, Breckpot J, Devriendt K, Stewart H, Banos-Pinero B, Mehta S, Sandford R, Dunn C, Mathevet R, van Maldergem L, Piard J, Brischoux-Boucher E, Vitobello A, Faivre L, Bournez M, Tran-Mau F, Maystadt I, Fernández-Jaén A, Alvarez S, García-Prieto ID, Alkuraya FS, Alsaif HS, Rahbeeni Z, El-Akouri K, Al-Mureikhi M, Spillmann RC, Shashi V, Sanchez-Lara PA, Graham JM Jr, Roberts A, Chorin O, Evrony GD, Kraatari-Tiri M, Dudding-Byth T, Richardson A, Hunt D, Hamilton L, Dyack S, Mendelsohn BA, Rodríguez N, Sánchez-Martínez R, Tenorio-Castaño J, Nevado J, Lapunzina P, Tirado P, Carminho Amaro Rodrigues MT, Quteineh L, Innes AM, Kline AD, Au PYB, Weksberg R., Free PMC Article

    10/15/2022
    Long Noncoding RNA LINC00941 Promotes Cell Proliferation and Invasion by Interacting with hnRNPK in Oral Squamous Cell Carcinoma.

    Long Noncoding RNA LINC00941 Promotes Cell Proliferation and Invasion by Interacting with hnRNPK in Oral Squamous Cell Carcinoma.
    Liu J, Li Z, Zhang T, Wang C, Chen W, Zhang D, Wang J.

    07/30/2022
    CircRFX3 Up-regulates Its Host Gene RFX3 to Facilitate Tumorigenesis and Progression of Glioma.

    CircRFX3 Up-regulates Its Host Gene RFX3 to Facilitate Tumorigenesis and Progression of Glioma.
    Qian Y, Cheng B, Luo J, Hu Y, Gao L, Cheng H.

    06/25/2022
    Heterogeneous nuclear ribonucleoprotein K promotes the progression of lung cancer by inhibiting the p53-dependent signaling pathway.

    Heterogeneous nuclear ribonucleoprotein K promotes the progression of lung cancer by inhibiting the p53-dependent signaling pathway.
    Li M, Yang X, Zhang G, Wang L, Zhu Z, Zhang W, Huang H, Gao R., Free PMC Article

    05/7/2022
    PROX1 promotes breast cancer invasion and metastasis through WNT/beta-catenin pathway via interacting with hnRNPK.

    PROX1 promotes breast cancer invasion and metastasis through WNT/β-catenin pathway via interacting with hnRNPK.
    Zhu L, Tian Q, Gao H, Wu K, Wang B, Ge G, Jiang S, Wang K, Zhou C, He J, Liu P, Ren Y, Wang B., Free PMC Article

    04/30/2022
    HnRNPK and lysine specific histone demethylase-1 regulates IP-10 mRNA stability in monocytes.

    HnRNPK and lysine specific histone demethylase-1 regulates IP-10 mRNA stability in monocytes.
    Natarajan K, Sundaramoorthy A, Shanmugam N.

    04/16/2022
    LCDR regulates the integrity of lysosomal membrane by hnRNP K-stabilized LAPTM5 transcript and promotes cell survival.

    LCDR regulates the integrity of lysosomal membrane by hnRNP K-stabilized LAPTM5 transcript and promotes cell survival.
    Yang X, Wen Y, Liu S, Duan L, Liu T, Tong Z, Wang Z, Gu Y, Xi Y, Wang X, Luo D, Zhang R, Liu Y, Wang Y, Cheng T, Jiang S, Zhu X, Yang X, Pan Y, Cheng S, Ye Q, Chen J, Xu X, Gao S., Free PMC Article

    02/26/2022
    Mass Spectrometry and Computer Simulation Predict the Interactions of AGPS and HNRNPK in Glioma.

    Mass Spectrometry and Computer Simulation Predict the Interactions of AGPS and HNRNPK in Glioma.
    Zhou W, Liu Y, Li H, Song Z, Ma Y, Zhu Y., Free PMC Article

    01/15/2022
    Caveolin-1-driven membrane remodelling regulates hnRNPK-mediated exosomal microRNA sorting in cancer.

    Caveolin-1-driven membrane remodelling regulates hnRNPK-mediated exosomal microRNA sorting in cancer.
    Robinson H, Ruelcke JE, Lewis A, Bond CS, Fox AH, Bharti V, Wani S, Cloonan N, Lai A, Margolin D, Li L, Salomon C, Richards RS, Farrell A, Gardiner RA, Parton RG, Cristino AS, Hill MM., Free PMC Article

    01/15/2022
    Circ-GALNT16 restrains colorectal cancer progression by enhancing the SUMOylation of hnRNPK.

    Circ-GALNT16 restrains colorectal cancer progression by enhancing the SUMOylation of hnRNPK.
    Peng C, Tan Y, Yang P, Jin K, Zhang C, Peng W, Wang L, Zhou J, Chen R, Wang T, Jin C, Ji J, Feng Y, Tang J, Sun Y., Free PMC Article

    01/8/2022
    SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.

    SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.
    Ren D, Sun Y, Zhang D, Li D, Liu Z, Jin X, Wu H.

    01/8/2022
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