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    ANXA1 annexin A1 [ Homo sapiens (human) ]

    Gene ID: 301, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity.

    Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity.
    Fang L, Liu C, Jiang ZZ, Wang M, Geng K, Xu Y, Zhu Y, Fu Y, Xue J, Shan W, Zhang Q, Chen J, Chen J, Zhao M, Guo Y, Siu KWM, Chen YE, Xu Y, Liu D, Zheng L., Free PMC Article

    10/3/2024
    TAZ downregulated ANXA1 expression to modulate myeloma cell interactions with bone marrow mesenchymal stromal cells.

    TAZ downregulated ANXA1 expression to modulate myeloma cell interactions with bone marrow mesenchymal stromal cells.
    Abegunde SO, Grieve S, Reiman T.

    09/27/2024
    Annexins A1 and A2 Accumulate and Are Immobilized at Cross-Linked Membrane-Membrane Interfaces.

    Annexins A1 and A2 Accumulate and Are Immobilized at Cross-Linked Membrane-Membrane Interfaces.
    Berg Klenow M, Iversen C, Wendelboe Lund F, Mularski A, Busk Heitmann AS, Dias C, Nylandsted J, Simonsen AC.

    07/26/2024
    Annexin A1 protects epidermal stem cells against ultraviolet-B irradiation-induced mitochondrial dysfunction.

    Annexin A1 protects epidermal stem cells against ultraviolet-B irradiation-induced mitochondrial dysfunction.
    Ge L, Chen W, Wei F.

    06/27/2024
    PRMT6 Promotes the Immune Evasion of Gastric Cancer by Upregulating ANXA1.

    PRMT6 Promotes the Immune Evasion of Gastric Cancer by Upregulating ANXA1.
    Xu L, Zhang F, Yu B, Jia S, Fan S.

    06/14/2024
    Mitigation of acute lung injury by human bronchial epithelial cell-derived extracellular vesicles via ANXA1-mediated FPR signaling.

    Mitigation of acute lung injury by human bronchial epithelial cell-derived extracellular vesicles via ANXA1-mediated FPR signaling.
    Fujita Y, Kadota T, Kaneko R, Hirano Y, Fujimoto S, Watanabe N, Kizawa R, Ohtsuka T, Kuwano K, Ochiya T, Araya J., Free PMC Article

    05/23/2024
    Loss of Endothelial Annexin A1 Aggravates Inflammation-Induched Vascular Aging.

    Loss of Endothelial Annexin A1 Aggravates Inflammation-Induched Vascular Aging.
    You Q, Ke Y, Chen X, Yan W, Li D, Chen L, Wang R, Yu J, Hong H., Free PMC Article

    05/7/2024
    An overview of the regulatory role of annexin A1 in the tumor microenvironment and its prospective clinical application (Review).

    An overview of the regulatory role of annexin A1 in the tumor microenvironment and its prospective clinical application (Review).
    Gao K, Li X, Luo S, Zhao L., Free PMC Article

    04/4/2024
    Annexin A1 may contribute to the morphological changes in podocytes by mediating endocytic vesicle fusion and transport via promotion of SNARE assembly in idiopathic membranous nephropathy.

    Annexin A1 may contribute to the morphological changes in podocytes by mediating endocytic vesicle fusion and transport via promotion of SNARE assembly in idiopathic membranous nephropathy.
    Song L, Shen W, Wang L, Song J, Tu W, Ke B, Fang X.

    02/6/2024
    Glioma-derived ANXA1 suppresses the immune response to TLR3 ligands by promoting an anti-inflammatory tumor microenvironment.

    Glioma-derived ANXA1 suppresses the immune response to TLR3 ligands by promoting an anti-inflammatory tumor microenvironment.
    Zheng Y, Jiang H, Yang N, Shen S, Huang D, Jia L, Ling J, Xu L, Li M, Yu K, Ren X, Cui Y, Lan X, Lin S, Lin X., Free PMC Article

    01/5/2024
    The expression of annexin-A1 in esophageal squamous cell carcinoma and its association with the biological behavior of the primary human esophageal squamous carcinoma cell line.

    The expression of annexin-A1 in esophageal squamous cell carcinoma and its association with the biological behavior of the primary human esophageal squamous carcinoma cell line.
    Li XJ, Li J, Zhang QQ, Su LP, Guo Y, Gong XL, Yao JJ, Wang L, Zhang ZQ.

    12/20/2023
    Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s.

    Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s.
    Irie M, Kabata H, Sasahara K, Kurihara M, Shirasaki Y, Kamatani T, Baba R, Matsusaka M, Koga S, Masaki K, Miyata J, Araki Y, Kikawada T, Kabe Y, Suematsu M, Yamagishi M, Uemura S, Moro K, Fukunaga K.

    10/12/2023
    ANXA1 Promotes Tumor Immune Evasion by Binding PARP1 and Upregulating Stat3-Induced Expression of PD-L1 in Multiple Cancers.

    ANXA1 Promotes Tumor Immune Evasion by Binding PARP1 and Upregulating Stat3-Induced Expression of PD-L1 in Multiple Cancers.
    Xiao D, Zeng T, Zhu W, Yu ZZ, Huang W, Yi H, Lu SS, Feng J, Feng XP, Wu D, Wen Q, Zhou JH, Yuan L, Zhuang W, Xiao ZQ.

    10/5/2023
    Tissue plasminogen activator receptor ANXA2 and its complementary regulator anti-inflammatory ANXA1 as prognostic indicators of inflammatory response in COVID-19 pathogenesis.

    Tissue plasminogen activator receptor ANXA2 and its complementary regulator anti-inflammatory ANXA1 as prognostic indicators of inflammatory response in COVID-19 pathogenesis.
    Shenoy RD, Nithin Kuriakose, Vijaykrishnaraj M, Patil P, Jayaswamy PK, Alagundagi DB, Shetty P.

    08/31/2023
    Targeting of Annexin A1 in Tumor-associated Macrophages as a therapeutic strategy for hepatocellular carcinoma.

    Targeting of Annexin A1 in Tumor-associated Macrophages as a therapeutic strategy for hepatocellular carcinoma.
    Song Z, Wang X, Liu X, Luo Y, Qiu J, Yin A, Liu Y, Yi H, Xiao Z, Li A.

    06/25/2023
    Salivary annexin A1: A candidate biomarker for periodontitis.

    Salivary annexin A1: A candidate biomarker for periodontitis.
    Casarin RCV, Salmon CR, Stolf CS, Paz HES, Rangel TP, Domingues RR, Pauletti BA, Paes-Leme AF, Araújo C, Santamaria MP, Ruiz KS, Monteiro MF.

    06/21/2023
    The Multifaceted Role of Annexin A1 in Viral Infections.

    The Multifaceted Role of Annexin A1 in Viral Infections.
    Resende F, Araújo S, Tavares LP, Teixeira MM, Costa VV., Free PMC Article

    05/23/2023
    Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing's sarcoma.

    Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing's sarcoma.
    Shi X, Wu Y, Tang L, Ni H, Xu Y., Free PMC Article

    04/12/2023
    ANXA1 mutation analysis in Italian patients with early onset PD.

    ANXA1 mutation analysis in Italian patients with early onset PD.
    Gagliardi M, Procopio R, Talarico M, Quattrone A, Arabia G, Morelli M, D'Amelio M, Malanga D, Bonapace G, Quattrone A, Annesi G.

    03/31/2023
    Annexin A1 induces oxaliplatin resistance of gastric cancer through autophagy by targeting PI3K/AKT/mTOR.

    Annexin A1 induces oxaliplatin resistance of gastric cancer through autophagy by targeting PI3K/AKT/mTOR.
    Ren J, Hu Z, Niu G, Xia J, Wang X, Hong R, Gu J, Wang D, Ke C.

    02/23/2023
    Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis.

    Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis.
    Fankhaenel M, Hashemi FSG, Mourao L, Lucas E, Hosawi MM, Skipp P, Morin X, Scheele CLGJ, Elias S., Free PMC Article

    02/13/2023
    Knockdown of Annexin A1 induces apoptosis, causing G2/M arrest and facilitating phagocytosis activity in human leukemia cell lines.

    Knockdown of Annexin A1 induces apoptosis, causing G2/M arrest and facilitating phagocytosis activity in human leukemia cell lines.
    Hasan M, Kumolosasi E, Jantan I, Jasamai M, Nazarudin N.

    01/28/2023
    Extracellular vesicles-transferred SBSN drives glioma aggressiveness by activating NF-kappaB via ANXA1-dependent ubiquitination of NEMO.

    Extracellular vesicles-transferred SBSN drives glioma aggressiveness by activating NF-κB via ANXA1-dependent ubiquitination of NEMO.
    Chen H, Chen X, Zhang Z, Bao W, Gao Z, Li D, Xie X, Zhou P, Yang C, Zhou Z, Pan J, Kuang X, Tang R, Feng Z, Zhou L, Zhu D, Yang J, Wang L, Huang H, Tang D, Liu J, Jiang L.

    12/10/2022
    Endothelial CYP2J2 overexpression restores the BRB via METTL3-mediated ANXA1 upregulation.

    Endothelial CYP2J2 overexpression restores the BRB via METTL3-mediated ANXA1 upregulation.
    Zhao B, Huang J, Lou X, Yao K, Ye M, Mou Q, Wen Z, Duan Q, Zhang H, Zhao Y.

    11/12/2022
    Annexin-1 is an oncogene in glioblastoma and causes tumour immune escape through the indirect upregulation of interleukin-8.

    Annexin-1 is an oncogene in glioblastoma and causes tumour immune escape through the indirect upregulation of interleukin-8.
    Chen R, Chen C, Han N, Guo W, Deng H, Wang Y, Ding Y, Zhang M., Free PMC Article

    08/6/2022
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