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    SLC40A1 solute carrier family 40 member 1 [ Homo sapiens (human) ]

    Gene ID: 30061, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Influence of SLC40A1 on Cytokine Interactions and Immune Infiltration in Glioblastoma.

    Influence of SLC40A1 on Cytokine Interactions and Immune Infiltration in Glioblastoma.
    Jiang J, Duan R, Zhu J, Yan J, Ye J, Luo C.

    08/9/2024
    Insights into the role of glycerophospholipids on the iron export function of SLC40A1 and the molecular mechanisms of ferroportin disease.

    Insights into the role of glycerophospholipids on the iron export function of SLC40A1 and the molecular mechanisms of ferroportin disease.
    Debbiche R, Elbahnsi A, Uguen K, Ka C, Callebaut I, Le Gac G.

    07/28/2024
    Inhibiting DNA methyltransferase DNMT3B confers protection against ferroptosis in nucleus pulposus and ameliorates intervertebral disc degeneration via upregulating SLC40A1.

    Inhibiting DNA methyltransferase DNMT3B confers protection against ferroptosis in nucleus pulposus and ameliorates intervertebral disc degeneration via upregulating SLC40A1.
    Chen J, Yang X, Li Q, Ma J, Li H, Wang L, Chen Z, Quan Z.

    06/3/2024
    PRPF19 promotes the proliferation, migration, and inhibits autophagy in prostate cancer by suppressing SLC40A1.

    PRPF19 promotes the proliferation, migration, and inhibits autophagy in prostate cancer by suppressing SLC40A1.
    Zhang G, Zhang W, Dan M, Zou F, Qiu C, Sun C.

    11/25/2023
    Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation.

    Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation.
    Ohta K, Ito M, Chida T, Nakashima K, Sakai S, Kanegae Y, Kawasaki H, Aoshima T, Takabayashi S, Takahashi H, Kawata K, Shoji I, Sawasaki T, Suda T, Suzuki T., Free PMC Article

    08/31/2023
    Mechanism of Ca[2+] transport by ferroportin.

    Mechanism of Ca(2+) transport by ferroportin.
    Shen J, Wilbon AS, Zhou M, Pan Y., Free PMC Article

    02/4/2023
    MAFG-AS1/MAFG positive feedback loop contributes to cisplatin resistance in bladder urothelial carcinoma through antagonistic ferroptosis.

    MAFG-AS1/MAFG positive feedback loop contributes to cisplatin resistance in bladder urothelial carcinoma through antagonistic ferroptosis.
    Xiang L, Zeng Q, Liu J, Xiao M, He D, Zhang Q, Xie D, Deng M, Zhu Y, Liu Y, Bo H, Liu X, Zhou M, Xiong W, Zhou Y, Zhou J, Li X, Cao K.

    01/28/2023
    Assessment of iron overload in a cohort of Sri Lankan patients with transfusion dependent beta thalassaemia and its correlation with pathogenic variants in HBB, HFE, SLC40A1, and TFR2 genes.

    Assessment of iron overload in a cohort of Sri Lankan patients with transfusion dependent beta thalassaemia and its correlation with pathogenic variants in HBB, HFE, SLC40A1, and TFR2 genes.
    Dissanayake R, Samarasinghe N, Waidyanatha S, Pathirana S, Neththikumara N, Dissanayake VHW, Wetthasinghe K, Gooneratne L, Wickramasinghe P., Free PMC Article

    06/25/2022
    MicroRNA-4735-3p Facilitates Ferroptosis in Clear Cell Renal Cell Carcinoma by Targeting SLC40A1.

    MicroRNA-4735-3p Facilitates Ferroptosis in Clear Cell Renal Cell Carcinoma by Targeting SLC40A1.
    Zhu C, Song Z, Chen Z, Lin T, Lin H, Xu Z, Ai F, Zheng S., Free PMC Article

    06/11/2022
    Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases.

    Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases.
    Raha AA, Biswas A, Henderson J, Chakraborty S, Holland A, Friedland RP, Mukaetova-Ladinska E, Zaman S, Raha-Chowdhury R., Free PMC Article

    04/16/2022
    UBA6 and NDFIP1 regulate the degradation of ferroportin.

    UBA6 and NDFIP1 regulate the degradation of ferroportin.
    Traeger L, Wiegand SB, Sauer AJ, Corman BHP, Peneyra KM, Wunderer F, Fischbach A, Bagchi A, Malhotra R, Zapol WM, Bloch DB., Free PMC Article

    04/16/2022
    Estimates of West African Ancestry in African Americans Using Alleles of Iron-Related Genes HJV, SLC40A1, and TFR2.

    Estimates of West African Ancestry in African Americans Using Alleles of Iron-Related Genes HJV, SLC40A1, and TFR2.
    Barton JC, Wiener HW, Acton RT.

    04/2/2022
    Ferroportin and FBXL5 as Prognostic Markers in Advanced Stage Clear Cell Renal Cell Carcinoma.

    Ferroportin and FBXL5 as Prognostic Markers in Advanced Stage Clear Cell Renal Cell Carcinoma.
    Park CK, Heo J, Ham WS, Choi YD, Shin SJ, Cho NH., Free PMC Article

    02/12/2022
    Upregulation of miR-18a-5p promotes the proliferation of prostate cancer via inhibiting the expression of SLC40A1.

    Upregulation of miR-18a-5p promotes the proliferation of prostate cancer via inhibiting the expression of SLC40A1.
    Liang B, Zhou C, Cui S, Lu H, Xu R, Xue D, Zou S, He X.

    01/15/2022
    Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth.

    Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth.
    Shekoohi S, Rajasekaran S, Patel D, Yang S, Liu W, Huang S, Yu X, Witt SN., Free PMC Article

    12/11/2021
    Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis.

    Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis.
    Cai C, Zeng D, Gao Q, Ma L, Zeng B, Zhou Y, Wang H., Free PMC Article

    11/6/2021
    Gene interfered-ferroptosis therapy for cancers.

    Gene interfered-ferroptosis therapy for cancers.
    Gao J, Luo T, Wang J., Free PMC Article

    10/9/2021
    Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.

    Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
    Lu S, Song Y, Luo R, Li S, Li G, Wang K, Liao Z, Wang B, Ke W, Xiang Q, Chen C, Wu X, Zhang Y, Ling L, Yang C., Free PMC Article

    09/11/2021
    Downregulation of FPN1 acts as a prognostic biomarker associated with immune infiltration in lung cancer.

    Downregulation of FPN1 acts as a prognostic biomarker associated with immune infiltration in lung cancer.
    Liu B, Song Z, Fan Y, Zhang G, Cao P, Li D, Liu X, Chang Y, Tan K., Free PMC Article

    07/24/2021
    Ferroportin disease: A novel SLC40A1 mutation.

    Ferroportin disease: A novel SLC40A1 mutation.
    Ravasi G, Pelucchi S, Russo A, Mariani R, Piperno A.

    07/24/2021
    Insights into the Role of the Discontinuous TM7 Helix of Human Ferroportin through the Prism of the Asp325 Residue.

    Insights into the Role of the Discontinuous TM7 Helix of Human Ferroportin through the Prism of the Asp325 Residue.
    Le Tertre M, Elbahnsi A, Ka C, Callebaut I, Le Gac G., Free PMC Article

    07/17/2021
    Splicing analysis of SLC40A1 missense variations and contribution to hemochromatosis type 4 phenotypes.

    Splicing analysis of SLC40A1 missense variations and contribution to hemochromatosis type 4 phenotypes.
    Le Tertre M, Ka C, Raud L, Berlivet I, Gourlaouen I, Richard G, Uguen K, Chen JM, FĂ©rec C, Fichou Y, Le Gac G.

    07/3/2021
    Iron Availability in Tissue Microenvironment: The Key Role of Ferroportin.

    Iron Availability in Tissue Microenvironment: The Key Role of Ferroportin.
    Gammella E, Correnti M, Cairo G, Recalcati S., Free PMC Article

    04/24/2021
    The role of cellular iron deficiency in controlling iron export.

    The role of cellular iron deficiency in controlling iron export.
    Link C, Knopf JD, Marques O, Lemberg MK, Muckenthaler MU.

    04/17/2021
    miR-194-5p inhibits SLC40A1 expression to induce cisplatin resistance in ovarian cancer.

    miR-194-5p inhibits SLC40A1 expression to induce cisplatin resistance in ovarian cancer.
    Wu J, Zhang L, Wu S, Yi X, Liu Z.

    04/3/2021
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