| The phenotypic and genotypic spectrum of individuals with mono- or biallelic ANK3 variants. | The phenotypic and genotypic spectrum of individuals with mono- or biallelic ANK3 variants.
Furia F, Levy AM, Theunis M, Bamshad MJ, Bartos MN, Bijlsma EK, Brancati F, Cejudo L, Chong JX, De Luca C, Dean SJ, Egense A, Goel H, Guenzel AJ, Hüffmeier U, Legius E, Mancini GMS, Marcos-Alcalde I, Niclass T, Planes M, Redon S, Ros-Pardo D, Rouault K, Schot R, Schuhmann S, Shen JJ, Tao AM, Thiffault I, Van Esch H, Wentzensen IM, Barakat TS, Møller RS, Gomez-Puertas P, Chung WK, Gardella E, Tümer Z., | 10/15/2024 |
| Effects of CACNA1C and ANK3 on cognitive function in patients with bipolar disorder. | Effects of CACNA1C and ANK3 on cognitive function in patients with bipolar disorder.
Yang Y, Zhu Z, Hui L, Sun P. | 06/5/2024 |
| ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome. | ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome.
Shen G, Chen L, Liu Y, Zhu Q, Kang Y, Luo X, Wang F, Wang W., Free PMC Article | 05/20/2024 |
| Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance. | Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance.
Kong C, Qu X, Liu M, Xu W, Chen D, Zhang Y, Zhang S, Zhu F, Liu Z, Li J, Huang C, Wang C., Free PMC Article | 11/1/2023 |
| Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders. | Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders.
Aas M, Andreassen OA, Gjerstad J, Rødevand L, Hjell G, Johansen IT, Lunding SH, Ormerod MBEG, Lagerverg TV, Steen NE, Djurovic S, Akkouh I., Free PMC Article | 09/1/2023 |
| Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain. | Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain.
Holmgren A, Hansson L, Bjerkaas-Kjeldal K, Impellizzeri AAR, Gilfillan GD, Djurovic S, Hughes T., Free PMC Article | 04/9/2022 |
| ANK3 related neurodevelopmental disorders: expanding the spectrum of heterozygous loss-of-function variants. | ANK3 related neurodevelopmental disorders: expanding the spectrum of heterozygous loss-of-function variants.
Kloth K, Lozic B, Tagoe J, Hoffer MJV, Van der Ven A, Thiele H, Altmüller J, Kubisch C, Au PYB, Denecke J, Bijlsma EK, Lessel D., Free PMC Article | 02/5/2022 |
| A linkage and exome study of multiplex families with bipolar disorder implicates rare coding variants of ANK3 and additional rare alleles at 10q11-q21. | A linkage and exome study of multiplex families with bipolar disorder implicates rare coding variants of ANK3 and additional rare alleles at 10q11-q21.
Toma C, Shaw AD, Heath A, Pierce KD, Mitchell PB, Schofield PR, Fullerton JM., Free PMC Article | 12/11/2021 |
| Human ankyrins and their contribution to disease biology: An update. | Human ankyrins and their contribution to disease biology: An update.
Sharma N, Bham K, Senapati S. | 10/2/2021 |
| Overrepresentation of genetic variation in the AnkyrinG interactome is related to a range of neurodevelopmental disorders. | Overrepresentation of genetic variation in the AnkyrinG interactome is related to a range of neurodevelopmental disorders.
van der Werf IM, Jansen S, de Vries PF, Gerstmans A, van de Vorst M, Van Dijck A, de Vries BBA, Gilissen C, Hoischen A, Vissers LELM, Kooy RF, Vandeweyer G., Free PMC Article | 08/21/2021 |
| Age-related atrophy of cortical thickness and genetic effect of ANK3 gene in first episode MDD patients. | Age-related atrophy of cortical thickness and genetic effect of ANK3 gene in first episode MDD patients.
Cheng Y, Xu J, Dong C, Shen Z, Zhou C, Li N, Lu Y, Ran L, Xu L, Shan B, Xu X., Free PMC Article | 07/17/2021 |
| Axonal TAU Sorting Requires the C-terminus of TAU but is Independent of ANKG and TRIM46 Enrichment at the AIS. | Axonal TAU Sorting Requires the C-terminus of TAU but is Independent of ANKG and TRIM46 Enrichment at the AIS.
Bell M, Bachmann S, Klimek J, Langerscheidt F, Zempel H. | 07/10/2021 |
| Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP. | Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP.
Nelson AD, Caballero-Florán RN, Rodríguez Díaz JC, Hull JM, Yuan Y, Li J, Chen K, Walder KK, Lopez-Santiago LF, Bennett V, McInnis MG, Isom LL, Wang C, Zhang M, Jones KS, Jenkins PM., Free PMC Article | 03/20/2021 |
| this genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption | A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption.
Haaland ØA, Romanowska J, Gjerdevik M, Lie RT, Gjessing HK, Jugessur A., Free PMC Article | 06/20/2020 |
| This study indicates that ANK3 is related to AR signalling pathway and is associated with BC prognosis. | Utility of ankyrin 3 as a prognostic marker in androgen-receptor-positive breast cancer.
Kurozumi S, Joseph C, Raafat S, Sonbul S, Kariri Y, Alsaeed S, Pigera M, Alsaleem M, Nolan CC, Johnston SJ, Aleskandarany MA, Ogden A, Fujii T, Shirabe K, Martin SG, Alshankyty I, Mongan NP, Ellis IO, Green AR, Rakha EA. | 11/30/2019 |
| Study shows that an elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder. | Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder.
Hughes T, Sønderby IE, Polushina T, Hansson L, Holmgren A, Athanasiu L, Melbø-Jørgensen C, Hassani S, Hoeffding LK, Herms S, Bergen SE, Karlsson R, Song J, Rietschel M, Nöthen MM, Forstner AJ, Hoffmann P, Hultman CM, Landén M, Cichon S, Werge T, Andreassen OA, Le Hellard S, Djurovic S., Free PMC Article | 04/6/2019 |
| Polymorphism in ANK3 gene is associated with Fetal Alcohol Spectrum Disorders. | L1 coupling to ankyrin and the spectrin-actin cytoskeleton modulates ethanol inhibition of L1 adhesion and ethanol teratogenesis.
Dou X, Menkari C, Mitsuyama R, Foroud T, Wetherill L, Hammond P, Suttie M, Chen X, Chen SY, Charness ME, Collaborative Initiative on Fetal Alcohol Spectrum Disorders., Free PMC Article | 11/17/2018 |
| an association between ANK3 rs10994336, rs10994338, rs4948418 and rs958852 and schizophrenia risk in a northern Chinese Han population. | Association analysis of ANK3 gene variants with schizophrenia in a northern Chinese Han population.
Guo X, Zhang Y, Du J, Yang H, Ma Y, Li J, Yan M, Jin T, Liu X., Free PMC Article | 02/24/2018 |
| The combination of tract-based spatial statistics (TBSS) with genotyping can be powerful to unveil the role of white matter in bipolar disorder, in conjunction with risk genes, ANK3 and ZNF804A. | Association of increased genotypes risk for bipolar disorder with brain white matter integrity investigated with tract-based spatial statistics: Special Section on "Translational and Neuroscience Studies in Affective Disorders". Section Editor, Maria Nobile MD, PhD. This Section of JAD focuses on the relevance of translational and neuroscience studies in providing a better understanding of the neural basis of affective disorders. The main aim is to briefly summarise relevant research findings in clinical neuroscience with particular regards to specific innovative topics in mood and anxiety disorders.
Squarcina L, Houenou J, Altamura AC, Soares J, Brambilla P. | 02/10/2018 |
| A significant association was found between bipolar disorder and rs10994336 (OR=1.18; 95% confidence interval: 1.06-1.31; P=0.0027) as well as rs1938526 (OR=1.16; 95% confidence interval: 1.06-1.28; P=0.0016) in ANK3. | ANK3 gene polymorphisms and bipolar disorder: a meta-analysis.
Roby Y. | 01/27/2018 |
| Thus ANK3's important association with human bipolar susceptibility may arise from imbalance between AnkG function in interneurons and principal cells and resultant excessive circuit sensitivity and output. | Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder.
Lopez AY, Wang X, Xu M, Maheshwari A, Curry D, Lam S, Adesina AM, Noebels JL, Sun QQ, Cooper EC., Free PMC Article | 01/20/2018 |
| ANK3 expression is associated with androgen receptor stability, invasiveness, and lethal outcome in prostate cancer patients. | Ankyrin G expression is associated with androgen receptor stability, invasiveness, and lethal outcome in prostate cancer patients.
Wang T, Abou-Ouf H, Hegazy SA, Alshalalfa M, Stoletov K, Lewis J, Donnelly B, Bismar TA. | 01/6/2018 |
| Nonsense mutation in ANK3 was identified in a patient with speech impairment, intellectual disability and autistic features. | First de novo ANK3 nonsense mutation in a boy with intellectual disability, speech impairment and autistic features.
Kloth K, Denecke J, Hempel M, Johannsen J, Strom TM, Kubisch C, Lessel D. | 12/9/2017 |
| Decreases in UF FA were observed among BD subjects carrying the ANK3 rs9804190 risk allele (T), compared to CC and T-carrier control subjects and BD CC homozygotes. | Effects of ANK3 variation on gray and white matter in bipolar disorder.
Lippard ETC, Jensen KP, Wang F, Johnston JAY, Spencer L, Pittman B, Gelernter J, Blumberg HP., Free PMC Article | 11/18/2017 |
| we found significant associations between rs10994336 and the N170 during the facial affect processing across two independent samples of healthy adults. In both samples, the risk allele carriers (TT/TC) consistently showed reduced N170. Our result showed clear evidence that rs10994336 may impact on the early neural processes (as reflected in N170) of facial affect processing. | The ANK3 gene and facial affect processing: An ERP study.
Zhao W, Zhang Q, Yu P, Zhang Z, Chen X, Gu H, Zhai J, Chen M, Du B, Deng X, Ji F, Wang C, Xiang YT, Li D, Wu H, Dong Q, Luo Y, Li J, Chen C. | 09/23/2017 |