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    GPER1 G protein-coupled estrogen receptor 1 [ Homo sapiens (human) ]

    Gene ID: 2852, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Suppressing Expression of SERPINE1/PAI1 Through Activation of GPER1 Reduces Progression of Vulvar Carcinoma.

    Suppressing Expression of SERPINE1/PAI1 Through Activation of GPER1 Reduces Progression of Vulvar Carcinoma.
    Doelker T, Gallwas J, Gründker C., Free PMC Article

    11/6/2024
    GPR30 is a potential player between islet cells and ductal HCO3[-] secretion.

    GPR30 is a potential player between islet cells and ductal HCO(3)(-) secretion.
    Venglovecz V, Hegyi P.

    09/21/2024
    The GPR30 Receptor Is Involved in IL-6-Induced Metastatic Properties of MCF-7 Luminal Breast Cancer Cells.

    The GPR30 Receptor Is Involved in IL-6-Induced Metastatic Properties of MCF-7 Luminal Breast Cancer Cells.
    Tirado-Garibay AC, Ruiz-Barcenas B, Rescala-Ponce de León JI, Ochoa-Zarzosa A, López-Meza JE., Free PMC Article

    09/3/2024
    G-protein coupled estrogen receptor 1, amyloid-beta, and tau tangles in older adults.

    G-protein coupled estrogen receptor 1, amyloid-β, and tau tangles in older adults.
    Oveisgharan S, Yu L, de Paiva Lopes K, Petyuk VA, Tasaki S, Vialle R, Menon V, Wang Y, De Jager PL, Schneider JA, Bennett DA., Free PMC Article

    08/8/2024
    Selective Activation of G Protein-coupled Estrogen Receptor 1 Attenuates Atherosclerosis.

    Selective Activation of G Protein-coupled Estrogen Receptor 1 Attenuates Atherosclerosis.
    Haider MZ, Sahebkar A, Eid AH.

    08/4/2024
    Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells.

    Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells.
    Cirillo F, Spinelli A, Talia M, Scordamaglia D, Santolla MF, Grande F, Rizzuti B, Maggiolini M, Gérard C, Lappano R., Free PMC Article

    07/12/2024
    G-protein-coupled estrogen receptor 1 promotes peritoneal metastasis of gastric cancer through nicotinamide adenine dinucleotide kinase 1-mediated redox modulation.

    G-protein-coupled estrogen receptor 1 promotes peritoneal metastasis of gastric cancer through nicotinamide adenine dinucleotide kinase 1-mediated redox modulation.
    Wu T, Ding K, Wang C, Lin G, Xie C, Chen X, Li Q, Yu F, Mao Y, Hong W, Lu L, Li S.

    03/8/2024
    Regulatory mechanism of GPER in the invasion and migration of ectopic endometrial stromal cells in endometriosis.

    Regulatory mechanism of GPER in the invasion and migration of ectopic endometrial stromal cells in endometriosis.
    Shi H, Xu K, Huang M, Mao M, Ou J.

    02/8/2024
    G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the beta1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells.

    G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β(1)-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells.
    Tutzauer J, Serafin DS, Schmidt T, Olde B, Caron KM, Leeb-Lundberg LMF., Free PMC Article

    02/4/2024
    The detection of Gper1 as an important gene promoting jawbone regeneration in the context of estrogen deficiency.

    The detection of Gper1 as an important gene promoting jawbone regeneration in the context of estrogen deficiency.
    Feng Y, Wang H, Xu S, Huang J, Pei Q, Wang Z.

    01/29/2024
    GPER: An Estrogen Receptor Key in Metastasis and Tumoral Microenvironments.

    GPER: An Estrogen Receptor Key in Metastasis and Tumoral Microenvironments.
    Tirado-Garibay AC, Falcón-Ruiz EA, Ochoa-Zarzosa A, López-Meza JE., Free PMC Article

    11/7/2023
    The Role of G Protein-Coupled Estrogen Receptor (GPER) in Vascular Pathology and Physiology.

    The Role of G Protein-Coupled Estrogen Receptor (GPER) in Vascular Pathology and Physiology.
    Xu F, Ma J, Wang X, Wang X, Fang W, Sun J, Li Z, Liu J., Free PMC Article

    10/6/2023
    Activation of G-Protein-Coupled Estrogen Receptor 1 (GPER1) Reduces Progression of Vulvar Carcinoma Cells.

    Activation of G-Protein-Coupled Estrogen Receptor 1 (GPER1) Reduces Progression of Vulvar Carcinoma Cells.
    Loris J, Hanesch L, Bauerschmitz G, Gallwas J, Gründker C., Free PMC Article

    10/5/2023
    GPER1 Activation Exerts Anti-Tumor Activity in Multiple Myeloma.

    GPER1 Activation Exerts Anti-Tumor Activity in Multiple Myeloma.
    Gallo Cantafio ME, Torcasio R, Scionti F, Mesuraca M, Ronchetti D, Pistoni M, Bellizzi D, Passarino G, Morelli E, Neri A, Viglietto G, Amodio N., Free PMC Article

    09/29/2023
    PJA1 mediates the effects of astrocytic GPR30 on learning and memory in female mice.

    PJA1 mediates the effects of astrocytic GPR30 on learning and memory in female mice.
    Wang X, Jiang Y, Feng B, Ma X, Zhang K, Yang F, Liu Z, Yang L, Yue J, Lu L, Song D, Guo Q, Qi J, Li X, Wang M, Zhang H, Huang J, Zhao M, Liu S., Free PMC Article

    09/20/2023
    GPER governs the immune infiltration of gastric cancer and activates the NF-kappaB/ROS/Apoptosis pathway in gastric mucosal epithelium.

    GPER governs the immune infiltration of gastric cancer and activates the NF-κB/ROS/Apoptosis pathway in gastric mucosal epithelium.
    Yang X, Zhang J, Ma J, Huang J, Wang Y, Wang P, Wang F, Tang X.

    08/30/2023
    Transcription factor Kruppel-like factor 4 upregulated G protein-coupled receptor 30 alleviates intestinal inflammation and apoptosis, and protects intestinal integrity from intestinal ischemia-reperfusion injury.

    Transcription factor Krüppel-like factor 4 upregulated G protein-coupled receptor 30 alleviates intestinal inflammation and apoptosis, and protects intestinal integrity from intestinal ischemia-reperfusion injury.
    Yin J, Xie X, Yao J, Jin X, Jiang H, Ji C., Free PMC Article

    08/1/2023
    Connecting G protein-coupled estrogen receptor biomolecular mechanisms with the pathophysiology of preeclampsia: a review.

    Connecting G protein-coupled estrogen receptor biomolecular mechanisms with the pathophysiology of preeclampsia: a review.
    Alencar AKN, Swan KF, Pridjian G, Lindsey SH, Bayer CL., Free PMC Article

    07/3/2023
    Involvement of the G-Protein-Coupled Estrogen Receptor-1 (GPER) Signaling Pathway in Neurodegenerative Disorders: A Review.

    Involvement of the G-Protein-Coupled Estrogen Receptor-1 (GPER) Signaling Pathway in Neurodegenerative Disorders: A Review.
    Upadhayay S, Gupta R, Singh S, Mundkar M, Singh G, Kumar P.

    06/26/2023
    Casein kinase 1 controls the shuttling of epidermal growth factor receptor and estrogen receptor in endometrial carcinoma induced by breast cancer hormonal therapy: Relevance of GPER1/Src.

    Casein kinase 1 controls the shuttling of epidermal growth factor receptor and estrogen receptor in endometrial carcinoma induced by breast cancer hormonal therapy: Relevance of GPER1/Src.
    Hoang LN, Lee SJ.

    06/14/2023
    Knockdown of G Protein-coupled Estrogen Receptor 1 (GPER1) Enhances Tumor-supportive Properties in Cervical Carcinoma Cells.

    Knockdown of G Protein-coupled Estrogen Receptor 1 (GPER1) Enhances Tumor-supportive Properties in Cervical Carcinoma Cells.
    Ruckriegl S, Loris J, Wert K, Bauerschmitz G, Gallwas J, Gründker C., Free PMC Article

    04/26/2023
    The immunohistochemical expression of GPER and classical sex hormone receptors differs in adenomyosis and eutopic endometrium.

    The immunohistochemical expression of GPER and classical sex hormone receptors differs in adenomyosis and eutopic endometrium.
    Samartzis N, Kalaitzopoulos DR, Noske A, Ihnenfeld I, Hutmacher J, Imesch P, Samartzis EP.

    03/29/2023
    The Co-Expression of Estrogen Receptors ERalpha, ERbeta, and GPER in Endometrial Cancer.

    The Co-Expression of Estrogen Receptors ERα, ERβ, and GPER in Endometrial Cancer.
    Hojnik M, Sinreih M, Anko M, Hevir-Kene N, Knific T, Pirš B, Grazio SF, Rižner TL., Free PMC Article

    02/22/2023
    Identification of a human estrogen receptor alpha tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action.

    Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action.
    Jouffre B, Acramel A, Belnou M, Santolla MF, Talia M, Lappano R, Nemati F, Decaudin D, Khemtemourian L, Liu WQ, Maggiolini M, Eschalier A, Mallet C, Jacquot Y., Free PMC Article

    02/4/2023
    GPER1 links estrogens to centrosome amplification and chromosomal instability in human colon cells.

    GPER1 links estrogens to centrosome amplification and chromosomal instability in human colon cells.
    Bühler M, Fahrländer J, Sauter A, Becker M, Wistorf E, Steinfath M, Stolz A., Free PMC Article

    11/26/2022
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