| Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia. | Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia.
Zhang Y, Che N, Wang S, Meng J, Zhao N, Han J, Dong X, Li Y, Mo J, Zhao X, Liu T. | 09/27/2024 |
| RBM10 C761Y mutation induced oncogenic ASPM isoforms and regulated beta-catenin signaling in cholangiocarcinoma. | RBM10 C761Y mutation induced oncogenic ASPM isoforms and regulated β-catenin signaling in cholangiocarcinoma.
Chang J, Zhang Y, Zhou T, Qiao Q, Shan J, Chen Y, Jiang W, Wang Y, Liu S, Wang Y, Yu Y, Li C, Li X., Free PMC Article | 04/12/2024 |
| ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells. | ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells.
Chan TS, Cheng LH, Hsu CC, Yang PM, Liao TY, Hsieh HY, Lin PC, HuangFu WC, Chuu CP, Tsai KK., Free PMC Article | 03/13/2024 |
| ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11. | ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11.
Fang Q, Li Q, Qi Y, Pan Z, Feng T, Xin W. | 06/16/2023 |
| ASPM overexpression enhances cellular proliferation and migration and predicts worse prognosis for papillary renal cell carcinoma. | ASPM overexpression enhances cellular proliferation and migration and predicts worse prognosis for papillary renal cell carcinoma.
Li N, Chu J, Hu K, Zhang H, Li N, Chu JF, Hu KY, Zhang HY. | 06/15/2023 |
| The Multiple Mitotic Roles of the ASPM Orthologous Proteins: Insight into the Etiology of ASPM-Dependent Microcephaly. | The Multiple Mitotic Roles of the ASPM Orthologous Proteins: Insight into the Etiology of ASPM-Dependent Microcephaly.
Razuvaeva AV, Graziadio L, Palumbo V, Pavlova GA, Popova JV, Pindyurin AV, Bonaccorsi S, Somma MP, Gatti M., Free PMC Article | 04/12/2023 |
| ASPM Activates Hedgehog and Wnt Signaling to Promote Small Cell Lung Cancer Stemness and Progression. | ASPM Activates Hedgehog and Wnt Signaling to Promote Small Cell Lung Cancer Stemness and Progression.
Cheng LH, Hsu CC, Tsai HW, Liao WY, Yang PM, Liao TY, Hsieh HY, Chan TS, Tsai KK. | 03/17/2023 |
| Mutation screening of multiple Pakistani MCPH families revealed novel and recurrent protein-truncating mutations of ASPM. | Mutation screening of multiple Pakistani MCPH families revealed novel and recurrent protein-truncating mutations of ASPM.
Hussain S, Nawaz A, Hamid M, Ullah W, Khan IN, Afshan M, Rehman A, Nawaz H, Halswick J, Rehman SU, Ahmad S, Muzammal M, Muhammad N, Jan A, Khan S, Windpassinger C, Khan MA. | 01/7/2023 |
| ASPM promotes ATR-CHK1 activation and stabilizes stalled replication forks in response to replication stress. | ASPM promotes ATR-CHK1 activation and stabilizes stalled replication forks in response to replication stress.
Wu X, Xu S, Wang P, Wang ZQ, Chen H, Xu X, Peng B., Free PMC Article | 10/15/2022 |
| Novel and recurrent ASPM mutations of founder effect in Chinese population. | Novel and recurrent ASPM mutations of founder effect in Chinese population.
Li M, Luo J, Yang Q, Chen F, Chen J, Qin J, He W, Chen J, Yi S, Qin Z, Yi S, Huang L, Qiu X, Pan P, Luo J, Shen Y. | 08/13/2022 |
| Large Phenotypic Variation of Individuals from a Family with a Novel ASPM Mutation Associated with Microcephaly, Epilepsy, and Behavioral and Cognitive Deficits. | Large Phenotypic Variation of Individuals from a Family with a Novel ASPM Mutation Associated with Microcephaly, Epilepsy, and Behavioral and Cognitive Deficits.
von Wrede R, Schidlowski M, Huppertz HJ, Rüber T, Ivo A, Baumgartner T, Hallmann K, Zsurka G, Helmstaedter C, Surges R, Kunz WS., Free PMC Article | 05/7/2022 |
| A Two-Base Pair Deletion in IQ Repeats in ASPM Underlies Microcephaly in a Pakistani Family. | A Two-Base Pair Deletion in IQ Repeats in ASPM Underlies Microcephaly in a Pakistani Family.
Naqvi SF, Shabbir RMK, Tolun A, Basit S, Malik S. | 03/19/2022 |
| Two novel truncating variants of the ASPM gene identified in a nonconsanguineous Chinese family associated with primary microcephaly. | Two novel truncating variants of the ASPM gene identified in a nonconsanguineous Chinese family associated with primary microcephaly.
Xu S, Zhang W, Zhou R, Huang H, Chen W, Xiang W, Liu L, Song J. | 01/22/2022 |
| Tone and genes: New cross-linguistic data and methods support the weak negative effect of the ""derived"" allele of ASPM on tone, but not of Microcephalin. | Tone and genes: New cross-linguistic data and methods support the weak negative effect of the "derived" allele of ASPM on tone, but not of Microcephalin.
Dediu D., Free PMC Article | 11/22/2021 |
| Oncogenic role of abnormal spindlelike microcephalyassociated protein in lung adenocarcinoma. | Oncogenic role of abnormal spindle‑like microcephaly‑associated protein in lung adenocarcinoma.
Wang J, Liang J, Li H, Han J, Jiang J, Li Y, Feng Z, Zhao R, Tian H., Free PMC Article | 11/6/2021 |
| Novel Pathogenic Mutation Mapping of ASPM Gene in Consanguineous Pakistani Families with Primary Microcephaly. | Novel Pathogenic Mutation Mapping of ASPM Gene in Consanguineous Pakistani Families with Primary Microcephaly.
Batool T, Irshad S, Mahmood K. | 08/14/2021 |
| Abnormal spindle-like microcephaly-associated (ASPM) gene expression in posterior fossa brain tumors of childhood and adolescence. | Abnormal spindle-like microcephaly-associated (ASPM) gene expression in posterior fossa brain tumors of childhood and adolescence.
Cabral de Carvalho Corrêa D, Dias Oliveira I, Mascaro Cordeiro B, Silva FA, de Seixas Alves MT, Saba-Silva N, Capellano AM, Dastoli P, Cavalheiro S, Caminada de Toledo SR. | 08/14/2021 |
| A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons. | A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.
Garrett L, Chang YJ, Niedermeier KM, Heermann T, Enard W, Fuchs H, Gailus-Durner V, Angelis MH, Huttner WB, Wurst W, Hölter SM., Free PMC Article | 08/7/2021 |
| ASPM is a Novel Candidate Gene Associated with Colorectal Cancer Cell Growth. | ASPM is a Novel Candidate Gene Associated with Colorectal Cancer Cell Growth.
Yang Q, Qi M, Chen Y, Tian S, Liao F, Dong W. | 07/31/2021 |
| Aberrant ASPM expression mediated by transcriptional regulation of FoxM1 promotes the progression of gliomas. | Aberrant ASPM expression mediated by transcriptional regulation of FoxM1 promotes the progression of gliomas.
Zeng WJ, Cheng Q, Wen ZP, Wang JY, Chen YH, Zhao J, Gong ZC, Chen XP., Free PMC Article | 05/8/2021 |
| CCNB2, TOP2A, and ASPM Reflect the Prognosis of Hepatocellular Carcinoma, as Determined by Weighted Gene Coexpression Network Analysis. | CCNB2, TOP2A, and ASPM Reflect the Prognosis of Hepatocellular Carcinoma, as Determined by Weighted Gene Coexpression Network Analysis.
Zeng Y, He H, Zhang Y, Wang X, Yang L, An Z., Free PMC Article | 04/17/2021 |
| Evaluation of ASPM and TEF Gene Expressions as Potential Biomarkers for Bladder Cancer. | Evaluation of ASPM and TEF Gene Expressions as Potential Biomarkers for Bladder Cancer.
Saleh AA, Gohar SF, Hemida AS, Elgharbawy M, Soliman SE. | 01/9/2021 |
| Expression of ASPM in Lung Adenocarcinoma and Its Relationship with Development and Prognosis | [Expression of ASPM in Lung Adenocarcinoma and Its Relationship with Development and Prognosis].
Wang J, He Z, Duan R., Free PMC Article | 06/6/2020 |
| In pancreatic tumors, ASPM-isoform I is cytoplasmic-localized and regulates Wnt signaling and tumor stem cells through its antagonism with the E3 ubiquitin ligase of Dvl-2, whereas ASPM-isoform II is mainly nuclear-localized and regulates essential housekeeping functions of tumor cells. | The differential distributions of ASPM isoforms and their roles in Wnt signaling, cell cycle progression, and pancreatic cancer prognosis.
Hsu CC, Liao WY, Chan TS, Chen WY, Lee CT, Shan YS, Huang PJ, Hou YC, Li CR, Tsai KK., Free PMC Article | 04/25/2020 |
| in three colorectal cancers and two gastric cancers, observed ASPM somatic mutations, which consisted of a frameshift mutation by deletion of one base (c.5149delA (p. Ile1717fsX1)) or another frameshift mutation by duplication of one base (c.5149delA (p. Ile1717AsnfsX24)) in the A7 repeat | Frameshift Mutation of ASPM Gene in Colorectal Cancers with Regional Heterogeneity.
Choi EJ, Kim MS, Yoo NJ, Lee SH. | 09/7/2019 |