| Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells. | Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells.
Varga AJ, Nemeth IB, Kemeny L, Varga J, Tiszlavicz L, Kumar D, Dodd S, Simpson AWM, Buknicz T, Beynon R, Simpson D, Krenacs T, Dockray GJ, Varro A., Free PMC Article | 12/20/2023 |
| Anatomical basis of gastrin- and CCK-secreting cells and their functions. A review. | Anatomical basis of gastrin- and CCK-secreting cells and their functions. A review.
Iwanaga T. | 06/3/2023 |
| Correlation Study between Levels of Gastrin, Serum IGF-1, and GHBP and Growth and Development in Children with Short Stature Based on Big Data Analysis. | Correlation Study between Levels of Gastrin, Serum IGF-1, and GHBP and Growth and Development in Children with Short Stature Based on Big Data Analysis.
Hua C, Yu D., Free PMC Article | 09/10/2022 |
| Prevalence and predictors of colonoscopic findings in patients with autoimmune gastritis. | Prevalence and predictors of colonoscopic findings in patients with autoimmune gastritis.
Asfuroglu Kalkan E, Kalkan C, Gumussoy M, Gucbey O, Soykan I. | 04/2/2022 |
| Peptidomics of enteroendocrine cells and characterisation of potential effects of a novel preprogastrin derived-peptide on glucose tolerance in lean mice. | Peptidomics of enteroendocrine cells and characterisation of potential effects of a novel preprogastrin derived-peptide on glucose tolerance in lean mice.
Galvin SG, Larraufie P, Kay RG, Pitt H, Bernard E, McGavigan AK, Brant H, Hood J, Sheldrake L, Conder S, Atherton-Kemp D, Lu VB, O'Flaherty EAA, Roberts GP, Ämmälä C, Jermutus L, Baker D, Gribble FM, Reimann F., Free PMC Article | 01/29/2022 |
| Hypergastrinemia is associated with an increased risk of gastric adenocarcinoma with proximal location: A prospective population-based nested case-control study. | Hypergastrinemia is associated with an increased risk of gastric adenocarcinoma with proximal location: A prospective population-based nested case-control study.
Ness-Jensen E, Bringeland EA, Mattsson F, Mjønes P, Lagergren J, Grønbech JE, Waldum HL, Fossmark R., Free PMC Article | 08/7/2021 |
| Type I and type II Helicobacter pylori infection status and their impact on gastrin and pepsinogen level in a gastric cancer prevalent area. | Type I and type II Helicobacter pylori infection status and their impact on gastrin and pepsinogen level in a gastric cancer prevalent area.
Yuan L, Zhao JB, Zhou YL, Qi YB, Guo QY, Zhang HH, Khan MN, Lan L, Jia CH, Zhang YR, Ding SZ., Free PMC Article | 07/10/2021 |
| Diagnostic value of serum pepsinogen I, pepsinogen II, and gastrin-17 levels for population-based screening for early-stage gastric cancer. | Diagnostic value of serum pepsinogen I, pepsinogen II, and gastrin-17 levels for population-based screening for early-stage gastric cancer.
Wang Y, Zhu Z, Liu Z, Zhao Z, Xue X, Li X, Li P, Rong G, Ma Y., Free PMC Article | 01/9/2021 |
| Data suggest the mitogenic role of gastrin in activation of K-Ras protein (KRAS) during pancreatic carcinogenesis. | Endogenous Gastrin Collaborates With Mutant KRAS in Pancreatic Carcinogenesis.
Nadella S, Burks J, Huber M, Wang J, Cao H, Kallakury B, Tucker RD, Boca SM, Jermusyck A, Collins I, Vietsch EE, Pierobon M, Hodge KA, Cui W, Amundadottir LT, Petricoin E 3rd, Shivapurkar N, Smith JP. | 05/2/2020 |
| Serum pepsinogen (PG), gastrin, and Helicobacter pylori (H. pylori) IgG antibodies have become indicators for "serological biopsy" of the gastric mucosa lesion. | Significance of Serological Gastric Biopsy in Different Gastric Mucosal Lesions: an Observational Study.
Dong Z, Zhang X, Chen X, Zhang J. | 01/18/2020 |
| Study found a negative correlation between serum levels of cardiac troponin I and gastrin in patients with unstable angina pectoris undergoing percutaneous coronary intervention, suggesting a protective effect of gastrin in human cardiomyocytes. | Gastrin Protects Against Myocardial Ischemia/Reperfusion Injury via Activation of RISK (Reperfusion Injury Salvage Kinase) and SAFE (Survivor Activating Factor Enhancement) Pathways.
Yang X, Yue R, Zhang J, Zhang X, Liu Y, Chen C, Wang X, Luo H, Wang WE, Chen X, Wang HJ, Jose PA, Wang H, Zeng C., Free PMC Article | 11/23/2019 |
| feedback between the level of ghrelin and gastrin in the blood of patients with chronic gastritis and type 2 diabetes mellitus; with increasing levels of gastrin in the blood, the level of ghrelin in the blood decreases and vice versa | Interrelation between ghrelin and gastrin in patients with combination of chronic gastritis and type 2 diabetes mellitus.
Sirchak ES, Patskun SV. | 06/8/2019 |
| The same markers were also expressed in a proportion of adenocarcinomas supporting the view that gastrin is important in the development of gastric cancer | Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells.
Mjønes P, Nordrum IS, Sørdal Ø, Sagatun L, Fossmark R, Sandvik A, Waldum HL., Free PMC Article | 02/2/2019 |
| We concluded that low serum gastrin is related to increased risk of ER(+) BC development. The results also established that CCKBR/ERK/P65 signaling function is generally tumor suppressive in ER(+) BC, indicating therapies should focus on restoring, not inhibiting, CCKBR/ERK/P65 pathway activity. | Low serum gastrin associated with ER(+) breast cancer development via inactivation of CCKBR/ERK/P65 signaling.
Meng LL, Wang JL, Xu SP, Zu LD, Yan ZW, Zhang JB, Han YQ, Fu GH., Free PMC Article | 11/3/2018 |
| Study reveals that Galphas binds to RGS1 and plays a necessary role during RGS1mediated promotion of melanoma proliferation and migration. | Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation.
Sun MY, Wang Y, Zhu J, Lv C, Wu K, Wang XW, Xue CY. | 09/22/2018 |
| Gastrin and BCL2 apoptosis regulator (Bcl2) are highly expressed in gastric cancer tissues, and they are correlated with the clinicopathologic features. | [Expressions of gastrin and apoptosis-associated proteins involved in mitochondrial pathway in gastric cancer tissues and the clinical significance].
Feng L, Zhu J, Sun W, Zhao J, Liu Y. | 06/9/2018 |
| Everolimus down-regulates the systemic levels of gastrin and glucagon in patients with pancreatic neuroendocrine tumors. | Everolimus Effect on Gastrin and Glucagon in Pancreatic Neuroendocrine Tumors.
Pavel ME, Chen D, He W, Cushman S, Voi M, de Vries EGE, Baudin E, Yao JC. | 04/14/2018 |
| we suggest that gastrin contributes to the emergence of MDR of SGC7901 cells via the degradation of p27Kip1 | Gastrin induces multidrug resistance via the degradation of p27Kip1 in the gastric carcinoma cell line SGC7901.
Zhuang K, Zhang L, Zhang X, Tang H, Zhang J, Yan Y, Han K, Guo H. | 03/3/2018 |
| Results demonstrate that gastrin increases the expression of the autophagy markers MAP1LC3B-II and SQSTM1 in gastric adenocarcinoma cells. Gastrin induces autophagy via activation of the STK11-PRKAA2-ULK1 and that this signaling pathway is involved in increased migration and cell survival. | Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells.
Rao SV, Solum G, Niederdorfer B, Nørsett KG, Bjørkøy G, Thommesen L., Free PMC Article | 12/23/2017 |
| PTHLH is a gastrin-regulated growth factor that might contribute to gastric epithelial cell homeostasis. | Gastrin induces parathyroid hormone-like hormone expression in gastric parietal cells.
Al Menhali A, Keeley TM, Demitrack ES, Samuelson LC., Free PMC Article | 08/12/2017 |
| Gastrin is expressed in both insulin(+) and somatostatin(+) cells in adults with type 2 diabetes. | Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes.
Dahan T, Ziv O, Horwitz E, Zemmour H, Lavi J, Swisa A, Leibowitz G, Ashcroft FM, In't Veld P, Glaser B, Dor Y., Free PMC Article | 06/10/2017 |
| Gastrin induced ABCG2 expression by activating NF-kappaB and thereby modulated the side population proportion, tumor cell metastatic potential and invasion activity in pancreatic cancer. | Gastrin regulates ABCG2 to promote the migration, invasion and side populations in pancreatic cancer cells via activation of NF-κB signaling.
Wang J, Xin B, Wang H, He X, Wei W, Zhang T, Shen X. | 05/20/2017 |
| CTGF is overexpressed in gastric cancer and adjacent tissue compared to normal gastric tissue. Gastrin induces expression of CTGF in gastric epithelial cells. | Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion.
Bhandari S, Bakke I, Kumar J, Beisvag V, Sandvik AK, Thommesen L, Varro A, Nørsett KG. | 05/13/2017 |
| Data show that 6 of 20 primary pancreatic neuroendocrine tumors (PNETs) had positive staining for multiple hormones gastrin, insulin, glucagon, and somatostatin, and positive expression of 1 or more hormones was found in 9 of 12 nonfunctioning PNETs [NF-PNETs]) patients. | Different Hormonal Expression Patterns Between Primary Pancreatic Neuroendocrine Tumors and Metastatic Sites.
Kimura H, Ohtsuka T, Fujimoto T, Date K, Matsunaga T, Cases AI, Abe A, Mizuuchi Y, Miyasaka Y, Ito T, Oda Y, Nakamura M, Tanaka M. | 04/1/2017 |
| Gastrin role in gastric epithelial homeostasis and gastric carcinogenesis | Gastrokine 1 inhibits gastrin-induced cell proliferation.
Kim O, Yoon JH, Choi WS, Ashktorab H, Smoot DT, Nam SW, Lee JY, Park WS., Free PMC Article | 12/31/2016 |