| USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells. | USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells.
Karapurkar JK, Colaco JC, Suresh B, Tyagi A, Woo SH, Jo WJ, Ko N, Singh V, Hong SH, Oh SJ, Kim KS, Ramakrishna S., Free PMC Article | 03/20/2024 |
| CircMAST1 inhibits cervical cancer progression by hindering the N4-acetylcytidine modification of YAP mRNA. | CircMAST1 inhibits cervical cancer progression by hindering the N4-acetylcytidine modification of YAP mRNA.
Zhang C, Yuan L, Zou Q, Shao C, Jia Y, Li J, Liao Y, Zhao X, Wen W, Jing X, Yang G, Wang W, Jiang H, Yao S., Free PMC Article | 02/14/2024 |
| Mast1 mediates radiation-induced gastric injury via the P38 MAPK pathway. | Mast1 mediates radiation-induced gastric injury via the P38 MAPK pathway.
Ding W, Lu Y, Zhou A, Chen Y, Wang Z, Wang L, Tian Y. | 01/1/2022 |
| Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1. | Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1.
Pan C, Kang J, Hwang JS, Li J, Boese AC, Wang X, Yang L, Boggon TJ, Chen GZ, Saba NF, Shin DM, Magliocca KR, Jin L, Kang S., Free PMC Article | 09/4/2021 |
| MAST1 modulates neuronal differentiation and cell cycle exit via P27 in neuroblastoma cells. | MAST1 modulates neuronal differentiation and cell cycle exit via P27 in neuroblastoma cells.
Jing T, Ma J, Zhao H, Zhang J, Jiang N, Ma D., Free PMC Article | 07/24/2021 |
| Evaluating the Role of MAST1 as an Intellectual Disability Disease Gene: Identification of a Novel De Novo Variant in a Patient with Developmental Disabilities. | Evaluating the Role of MAST1 as an Intellectual Disability Disease Gene: Identification of a Novel De Novo Variant in a Patient with Developmental Disabilities.
Ben-Mahmoud A, Al-Shamsi AM, Ali BR, Al-Gazali L. | 02/13/2021 |
| Through a proteomics screen, we identified the heat shock protein 90 B (hsp90B) chaperone as a direct MAST1 binding partner essential for its stabilization. Targeting hsp90B sensitized cancer cells to cisplatin predominantly through MAST1 destabilization. Mechanistically, interaction of hsp90B with MAST1 blocked ubiquitination of MAST1 at lysines 317 and 545. | Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation.
Pan C, Chun J, Li D, Boese AC, Li J, Kang J, Umano A, Jiang Y, Song L, Magliocca KR, Chen ZG, Saba NF, Shin DM, Owonikoko TK, Lonial S, Jin L, Kang S., Free PMC Article | 06/13/2020 |
| This report showed that de novo MAST1 substitutions are present in patients with autism and microcephaly, raising the prospect that mutations in this gene give rise to a spectrum of neurodevelopmental diseases. | Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.
Tripathy R, Leca I, van Dijk T, Weiss J, van Bon BW, Sergaki MC, Gstrein T, Breuss M, Tian G, Bahi-Buisson N, Paciorkowski AR, Pagnamenta AT, Wenninger-Weinzierl A, Martinez-Reza MF, Landler L, Lise S, Taylor JC, Terrone G, Vitiello G, Del Giudice E, Brunetti-Pierri N, D'Amico A, Reymond A, Voisin N, Bernstein JA, Farrelly E, Kini U, Leonard TA, Valence S, Burglen L, Armstrong L, Hiatt SM, Cooper GM, Aldinger KA, Dobyns WB, Mirzaa G, Pierson TM, Baas F, Chelly J, Cowan NJ, Keays DA., Free PMC Article | 08/10/2019 |
| Overexpression of MAST1 or MAST2 gene fusions has a proliferative effect both in vitro and in vivo in breast cancer cell lines. | Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.
Robinson DR, Kalyana-Sundaram S, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM., Free PMC Article | 02/4/2012 |
| Discusses cloning of Sast, the mouse ortholog of human MAST1. | Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.
Lumeng C, Phelps S, Crawford GE, Walden PD, Barald K, Chamberlain JS. | 06/5/2009 |
| Discusses cloning of Sast124, the rat ortholog of MAST1. | Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions.
Yano R, Yap CC, Yamazaki Y, Muto Y, Kishida H, Okada D, Hashikawa T. | 06/5/2009 |