U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit [ Homo sapiens (human) ]

    Gene ID: 2146, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Homeobox B9 promotes the invasion and metastasis of hepatocellular carcinoma cells via the EZH2-MIR203A-SNAI2 axis.

    Homeobox B9 promotes the invasion and metastasis of hepatocellular carcinoma cells via the EZH2-MIR203A-SNAI2 axis.
    Zhang D, Qiu Y, Zhang W, Du D, Liu Y, Liu L, Li J, Chen Z, Yu X, Ye M, Wang W, Li Z, Shao J., Free PMC Article

    10/19/2024
    EZH2 specifically regulates ISL1 during embryonic urinary tract formation.

    EZH2 specifically regulates ISL1 during embryonic urinary tract formation.
    Mingardo E, Kalanithy JC, Dworschak G, Ishorst N, Yilmaz Ö, Lindenberg T, Hollstein R, Felger T, Angrand PO, Reutter H, Odermatt B., Free PMC Article

    10/9/2024
    EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells.

    EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells.
    Gallardo A, López-Onieva L, Belmonte-Reche E, Fernández-Rengel I, Serrano-Prados A, Molina A, Sánchez-Pozo A, Landeira D., Free PMC Article

    10/3/2024
    LncRNA CARMN facilitates odontogenic differentiation of dental pulp cells by impairing EZH2.

    LncRNA CARMN facilitates odontogenic differentiation of dental pulp cells by impairing EZH2.
    Li H, Huo S, He X, Guo D, Liu Y, Zheng L, Zhou X.

    09/24/2024
    MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling.

    MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling.
    Hu X, Liu Y, Shen H, Zhang T, Liang T., Free PMC Article

    09/17/2024
    TXNIP mediated by EZH2 regulated osteogenic differentiation in hBmscs and MC3T3-E1 cells through the modulation of oxidative stress and PI3K/AKT/Nrf2 pathway.

    TXNIP mediated by EZH2 regulated osteogenic differentiation in hBmscs and MC3T3-E1 cells through the modulation of oxidative stress and PI3K/AKT/Nrf2 pathway.
    Zhou W, Zhu C, Zhou F.

    09/3/2024
    A novel EZH2/NXPH4/CDKN2A axis is involved in regulating the proliferation and migration of non-small cell lung cancer cells.

    A novel EZH2/NXPH4/CDKN2A axis is involved in regulating the proliferation and migration of non-small cell lung cancer cells.
    Yang Z, Wei B, Qiao A, Yang P, Chen W, Zhen D, Qiu X.

    08/30/2024
    LINC01348 suppresses hepatocellular carcinoma metastasis through inhibition of SF3B3-mediated EZH2 pre-mRNA splicing.

    LINC01348 suppresses hepatocellular carcinoma metastasis through inhibition of SF3B3-mediated EZH2 pre-mRNA splicing.
    Lin YH, Wu MH, Liu YC, Lyu PC, Yeh CT, Lin KH.

    08/28/2024
    PRMT6 facilitates EZH2 protein stability by inhibiting TRAF6-mediated ubiquitination degradation to promote glioblastoma cell invasion and migration.

    PRMT6 facilitates EZH2 protein stability by inhibiting TRAF6-mediated ubiquitination degradation to promote glioblastoma cell invasion and migration.
    Wang J, Shen S, You J, Wang Z, Li Y, Chen Y, Tuo Y, Chen D, Yu H, Zhang J, Wang F, Pang X, Xiao Z, Lan Q, Wang Y., Free PMC Article

    08/23/2024
    TRIM37 interacts with EZH2 to epigenetically suppress PTCH1 and regulate stemness in glioma stem cells through sonic hedgehog pathway.

    TRIM37 interacts with EZH2 to epigenetically suppress PTCH1 and regulate stemness in glioma stem cells through sonic hedgehog pathway.
    Cai L, Liu Y, Li Y, Liu B, Cao Y, Yang W, Wang B, Sun T.

    08/23/2024
    NOP2 facilitates EZH2-mediated epithelial-mesenchymal transition by enhancing EZH2 mRNA stability via m5C methylation in lung cancer progression.

    NOP2 facilitates EZH2-mediated epithelial-mesenchymal transition by enhancing EZH2 mRNA stability via m5C methylation in lung cancer progression.
    Yang Y, Fan H, Liu H, Lou X, Xiao N, Zhang C, Chen H, Chen S, Gu H, Liu H, Wan J., Free PMC Article

    08/14/2024
    YTHDF1 promotes the osteolytic bone metastasis of breast cancer via inducing EZH2 and CDH11 translation.

    YTHDF1 promotes the osteolytic bone metastasis of breast cancer via inducing EZH2 and CDH11 translation.
    Wang S, Xu L, Wang D, Zhao S, Li K, Ma F, Yao Q, Zhang Y, Wu Z, Shao Y, Song S, Yan W.

    08/1/2024
    UBR7 in concert with EZH2 inhibits the TGF-beta signaling leading to extracellular matrix remodeling.

    UBR7 in concert with EZH2 inhibits the TGF-β signaling leading to extracellular matrix remodeling.
    Adhikari S, Singh V, Nandi S, Ghosal M, Raj NS, Khanna J, Bhattacharya A, Kabiraj A, Mondal A, Vasudevan M, Senapati D, Roy H, Sengupta K, Notani D, Das C.

    07/31/2024
    Enzyme-independent role of EZH2 in regulating cell cycle progression via the SKP2-KIP/CIP pathway.

    Enzyme-independent role of EZH2 in regulating cell cycle progression via the SKP2-KIP/CIP pathway.
    Colon T, Kou Z, Choi BH, Tran F, Zheng E, Dai W., Free PMC Article

    06/21/2024
    Identification and functional analysis of the hub Ferroptosis-Related gene EZH2 in diabetic kidney disease.

    Identification and functional analysis of the hub Ferroptosis-Related gene EZH2 in diabetic kidney disease.
    Wang H, Wang J, Ran Q, Leng Y, Liu T, Xiong Z, Zou D, Yang W.

    06/17/2024
    RBM15-Mediated N6-Methyl Adenosine (m6A) Modification of EZH2 Drives the Epithelial-Mesenchymal Transition of Cervical Cancer.

    RBM15-Mediated N6-Methyl Adenosine (m6A) Modification of EZH2 Drives the Epithelial-Mesenchymal Transition of Cervical Cancer.
    Wang R, Tan W.

    06/14/2024
    LncRNA DLG5-AS1 facilitates breast cancer cell proliferation and invasion by promoting EZH2-mediated transcriptional silencing of SFRP1.

    LncRNA DLG5-AS1 facilitates breast cancer cell proliferation and invasion by promoting EZH2-mediated transcriptional silencing of SFRP1.
    Cai Y, Liu Y, Sun Y, Ren Y.

    05/31/2024
    Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells.

    Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells.
    Jacksi M, Schad E, Tantos A., Free PMC Article

    05/20/2024
    MELK aggravates lung adenocarcinoma by regulating EZH2 ubiquitination and H3K27me3 histone methylation of LATS2.

    MELK aggravates lung adenocarcinoma by regulating EZH2 ubiquitination and H3K27me3 histone methylation of LATS2.
    Yu H, Xu X, Zhu L, Chen S, He J., Free PMC Article

    05/20/2024
    TP53 mutation is frequent in mantle cell lymphoma with EZH2 expression and have dismal outcome when both are present.

    TP53 mutation is frequent in mantle cell lymphoma with EZH2 expression and have dismal outcome when both are present.
    Kim DH, Siddiqui S, Jain P, Wang M, Thakral B, Li S, Miranda R, Vega F, Medeiros LJ, Ok CY.

    05/9/2024
    EZH2 Promotes Multiple Myeloma Progression via STAT3 Pathway Activation.

    EZH2 Promotes Multiple Myeloma Progression via STAT3 Pathway Activation.
    Wang Y, Tian J, Huang D, Gao Y, Lin H, Liu L, Wang A.

    04/30/2024
    Exosome miR-101-3p derived from bone marrow mesenchymal stem cells promotes radiotherapy sensitivity in non-small cell lung cancer by regulating DNA damage repair and autophagy levels through EZH2.

    Exosome miR-101-3p derived from bone marrow mesenchymal stem cells promotes radiotherapy sensitivity in non-small cell lung cancer by regulating DNA damage repair and autophagy levels through EZH2.
    Sun H, Zhu R, Guo X, Zhao P, Zhang R, Zhao Z, Zhou H.

    04/17/2024
    EZH2-interacting lncRNAs contribute to gastric tumorigenesis; a review on the mechanisms of action.

    EZH2-interacting lncRNAs contribute to gastric tumorigenesis; a review on the mechanisms of action.
    Mohebbi H, Esbati R, Hamid RA, Akhavanfar R, Radi UK, Siri G, Yazdani O.

    04/3/2024
    MAL expression downregulation through suppressive H3K27me3 marks at the promoter in HPV16-related cervical cancers is prognostically relevant and manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2.

    MAL expression downregulation through suppressive H3K27me3 marks at the promoter in HPV16-related cervical cancers is prognostically relevant and manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2.
    Sinha A, Ghosh A, Ghosh A, Mathai S, Bhaumik J, Mukhopadhyay A, Maitra A, Biswas NK, Sengupta S., Free PMC Article

    03/28/2024
    EZH2-mediated development of therapeutic resistance in cancer.

    EZH2-mediated development of therapeutic resistance in cancer.
    Kaur P, Shankar E, Gupta S.

    03/19/2024
    firstprevious page of 54 nextlast