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    Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 [ Mus musculus (house mouse) ]

    Gene ID: 20525, updated on 14-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis.

    Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis.
    Ardanaz CG, de la Cruz A, Minhas PS, Hernández-Martín N, Pozo MÁ, Valdecantos MP, Valverde ÁM, Villa-Valverde P, Elizalde-Horcada M, Puerta E, Ramírez MJ, Ortega JE, Urbiola A, Ederra C, Ariz M, Ortiz-de-Solórzano C, Fernández-Irigoyen J, Santamaría E, Karsenty G, Brüning JC, Solas M., Free PMC Article

    10/29/2024
    GLUT1 overexpression enhances CAR T cell metabolic fitness and anti-tumor efficacy.

    GLUT1 overexpression enhances CAR T cell metabolic fitness and anti-tumor efficacy.
    Shi Y, Kotchetkov IS, Dobrin A, Hanina SA, Rajasekhar VK, Healey JH, Sadelain M.,

    07/29/2024
    Expression of the monocarboxylate transporter MCT1 is required for virus-specific mouse CD8[+] T cell memory development.

    Expression of the monocarboxylate transporter MCT1 is required for virus-specific mouse CD8(+) T cell memory development.
    D'Aria S, Maquet C, Li S, Dhup S, Lepez A, Kohler A, Van Hée VF, Dadhich RK, Frenière M, Andris F, Nemazanyy I, Sonveaux P, Machiels B, Gillet L, Braun MY., Free PMC Article

    07/15/2024
    GLUT1 Promotes NLRP3 Inflammasome Activation of Airway Epithelium in Lipopolysaccharide-Induced Acute Lung Injury.

    GLUT1 Promotes NLRP3 Inflammasome Activation of Airway Epithelium in Lipopolysaccharide-Induced Acute Lung Injury.
    Li J, Li Y, Chen G, Liang Y, Xie J, Zhang S, Zhong K, Jiang T, Yi H, Tang H, Chen X.

    07/1/2024
    GLUT1 regulates the release of VEGF-A in the alveolar epithelium of lipopolysaccharide-induced acute lung injury.

    GLUT1 regulates the release of VEGF-A in the alveolar epithelium of lipopolysaccharide-induced acute lung injury.
    Liang Y, Zhang H, Li J, Wang X, Xie J, Li Y, Li J, Qian Y, Zhang H, Wang T, Tang H, Chen X.

    03/13/2024
    GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity.

    GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity.
    Bierling TEH, Gumann A, Ottmann SR, Schulz SR, Weckwerth L, Thomas J, Gessner A, Wichert M, Kuwert F, Rost F, Hauke M, Freudenreich T, Mielenz D, Jäck HM, Pracht K.

    03/5/2024
    GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma.

    GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma.
    Tang H, Guo Y, Gan S, Chen Z, Dong M, Lin L, Chen H, Ji X, Xian M, Shi X, Tao A, Lv Y, Yao L, Chen R, Li S, Li J.

    02/21/2024
    GLUT1 contributes to impaired epithelial tight junction in the late phase of acute lung injury.

    GLUT1 contributes to impaired epithelial tight junction in the late phase of acute lung injury.
    Tang H, Chen Z, Gan S, Liang Y, Zhang H, Yang C, Lin L, Guo Y, Li S, Li J, Yao L.

    12/22/2023
    Intermedin alleviates diabetic vascular calcification by inhibiting GLUT1 through activation of the cAMP/PKA signaling pathway.

    Intermedin alleviates diabetic vascular calcification by inhibiting GLUT1 through activation of the cAMP/PKA signaling pathway.
    Zhang YR, Liu SM, Chen Y, Zhang LS, Ji DR, Zhao J, Yu YR, Jia MZ, Tang CS, Huang W, Zhou YB, Chai SB, Qi YF.

    11/29/2023
    Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity.

    Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity.
    Rodriguez-Zabala M, Ramakrishnan R, Reinbach K, Ghosh S, Oburoglu L, Falqués-Costa A, Bellamkonda K, Ehinger M, Peña-Martínez P, Puente-Moncada N, Lilljebjörn H, Cammenga J, Pronk CJ, Lazarevic V, Fioretos T, Hagström-Andersson AK, Woods NB, Järås M., Free PMC Article

    09/19/2023
    miR-455-3p ameliorates pancreatic acinar cell injury by targeting Slc2a1.

    miR-455-3p ameliorates pancreatic acinar cell injury by targeting Slc2a1.
    Zhan Y, Chen C, Wu Z, Zhou F, Yu X., Free PMC Article

    07/10/2023
    Systemic Reduction of Glut1 Normalizes Retinal Dysfunction, Inflammation, and Oxidative Stress in the Retina of Spontaneous Type 2 Diabetic Mice.

    Systemic Reduction of Glut1 Normalizes Retinal Dysfunction, Inflammation, and Oxidative Stress in the Retina of Spontaneous Type 2 Diabetic Mice.
    Aiello JJ, Bogart MC, Chan WT, Holoman NC, Trobenter TD, Relf CE, Kleinman DM, De Vivo DC, Samuels IS., Free PMC Article

    06/23/2023
    Mustn1 ablation in skeletal muscle results in increased glucose tolerance concomitant with upregulated GLUT expression in male mice.

    Mustn1 ablation in skeletal muscle results in increased glucose tolerance concomitant with upregulated GLUT expression in male mice.
    Kim CJ, Singh C, Lee C, DiMagno K, O'Donnell M, Kaczmarek M, Ahmed A, Salvo-Schaich J, Perez A, Letsou W, Sepulveda MC, Ramos RL, Hadjiargyrou M., Free PMC Article

    06/2/2023
    Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndrome.

    Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndrome.
    Tayebi N, Leon-Ricardo B, McCall K, Mehinovic E, Engelstad K, Huynh V, Turner TN, Weisenberg J, Thio LL, Hruz P, Williams RSB, De Vivo DC, Petit V, Haller G, Gurnett CA., Free PMC Article

    05/19/2023
    GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc.

    GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc.
    Johnston SN, Silagi ES, Madhu V, Nguyen DH, Shapiro IM, Risbud MV., Free PMC Article

    04/27/2023
    Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake.

    Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake.
    McMillin SL, Evans PL, Taylor WM, Weyrauch LA, Sermersheim TJ, Welc SS, Heitmeier MR, Hresko RC, Hruz PW, Koumanov F, Holman GD, Abel ED, Witczak CA., Free PMC Article

    01/21/2023
    A mathematical model of GLUT1 modulation in rods and RPE and its differential impact in cell metabolism.

    A mathematical model of GLUT1 modulation in rods and RPE and its differential impact in cell metabolism.
    Aparicio A, Camacho ET, Philp NJ, Wirkus SA., Free PMC Article

    07/2/2022
    Lactate dehydrogenase regulates basal glucose uptake in adipocytes.

    Lactate dehydrogenase regulates basal glucose uptake in adipocytes.
    Minemura T, Fukuhara A, Otsuki M, Shimomura I.

    05/7/2022
    Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity.

    Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity.
    Li DD, Jawale CV, Zhou C, Lin L, Trevejo-Nunez GJ, Rahman SA, Mullet SJ, Das J, Wendell SG, Delgoffe GM, Lionakis MS, Gaffen SL, Biswas PS., Free PMC Article

    05/7/2022
    Analysis of glucose metabolism by (18)F-FDG-PET imaging and glucose transporter expression in a mouse model of intracerebral hemorrhage.

    Analysis of glucose metabolism by (18)F-FDG-PET imaging and glucose transporter expression in a mouse model of intracerebral hemorrhage.
    Han X, Ren H, Nandi A, Fan X, Koehler RC., Free PMC Article

    11/6/2021
    GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy.

    GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy.
    Ancey PB, Contat C, Boivin G, Sabatino S, Pascual J, Zangger N, Perentes JY, Peters S, Abel ED, Kirsch DG, Rathmell JC, Vozenin MC, Meylan E., Free PMC Article

    09/18/2021
    Alzheimer amyloid-beta- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood.

    Alzheimer amyloid-β- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood.
    Hendrix RD, Ou Y, Davis JE, Odle AK, Groves TR, Allen AR, Childs GV, Barger SW., Free PMC Article

    09/4/2021
    ATGL activity regulates GLUT1-mediated glucose uptake and lactate production via TXNIP stability in adipocytes.

    ATGL activity regulates GLUT1-mediated glucose uptake and lactate production via TXNIP stability in adipocytes.
    Beg M, Zhang W, McCourt AC, Enerbäck S., Free PMC Article

    08/28/2021
    Reduction of Glut1 in the Neural Retina But Not the RPE Alleviates Polyol Accumulation and Normalizes Early Characteristics of Diabetic Retinopathy.

    Reduction of Glut1 in the Neural Retina But Not the RPE Alleviates Polyol Accumulation and Normalizes Early Characteristics of Diabetic Retinopathy.
    Holoman NC, Aiello JJ, Trobenter TD, Tarchick MJ, Kozlowski MR, Makowski ER, De Vivo DC, Singh C, Sears JE, Samuels IS., Free PMC Article

    08/21/2021
    LncRNA HOTAIR regulates glucose transporter Glut1 expression and glucose uptake in macrophages during inflammation.

    LncRNA HOTAIR regulates glucose transporter Glut1 expression and glucose uptake in macrophages during inflammation.
    Obaid M, Udden SMN, Alluri P, Mandal SS., Free PMC Article

    08/14/2021
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