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    AHR aryl hydrocarbon receptor [ Homo sapiens (human) ]

    Gene ID: 196, updated on 11-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Modulatory Roles of AHR, FFAR2, FXR, and TGR5 Gene Expression in Metabolic-Associated Fatty Liver Disease and COVID-19 Outcomes.

    Modulatory Roles of AHR, FFAR2, FXR, and TGR5 Gene Expression in Metabolic-Associated Fatty Liver Disease and COVID-19 Outcomes.
    Buchynskyi M, Oksenych V, Kamyshna I, Vorobets I, Halabitska I, Kamyshnyi O., Free PMC Article

    11/7/2024
    Association of Estrogen Receptor-alpha and Aryl Hydrocarbon Receptor Gene Polymorphisms with Ischemic Stroke in an Egyptian Population: A Pilot Study.

    Association of Estrogen Receptor-α and Aryl Hydrocarbon Receptor Gene Polymorphisms with Ischemic Stroke in an Egyptian Population: A Pilot Study.
    Aboelroos SA, Segaey DGE, Elgawad AKA, Orabi M, Mohamed MH, Hassan NR.

    11/4/2024
    The aryl hydrocarbon receptor shapes monocyte transcriptional responses to interleukin-4 by prolonging STAT6 binding to promoters.

    The aryl hydrocarbon receptor shapes monocyte transcriptional responses to interleukin-4 by prolonging STAT6 binding to promoters.
    de Juan A, Tabtim-On D, Coillard A, Becher B, Goudot C, Segura E.

    10/25/2024
    The aryl hydrocarbon receptor pathway is a marker of lung cell activation but does not play a central pathologic role in engineered stone-associated silicosis.

    The aryl hydrocarbon receptor pathway is a marker of lung cell activation but does not play a central pathologic role in engineered stone-associated silicosis.
    Song Y, Yen S, Southam K, Gaskin S, Hoy RF, Zosky GR.

    10/18/2024
    MerTK[+] macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation.

    MerTK(+) macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation.
    Wu N, Li J, Li L, Yang L, Dong L, Shen C, Sha S, Fu Y, Dong E, Zheng F, Tan Z, Tao J., Free PMC Article

    10/10/2024
    Involvement of Aryl Hydrocarbon Receptor in Longevity and Healthspan: Insights from Humans, Mice, and C. elegans.

    Involvement of Aryl Hydrocarbon Receptor in Longevity and Healthspan: Insights from Humans, Mice, and C. elegans.
    Serna E, Verdú D, Valls A, Belenguer-Varea Á, Tarazona-Santabalbina FJ, Borrás C, Viña J., Free PMC Article

    10/4/2024
    PGRMC1 promotes NSCLC stemness phenotypes by disrupting TRIM56-mediated ubiquitination of AHR.

    PGRMC1 promotes NSCLC stemness phenotypes by disrupting TRIM56-mediated ubiquitination of AHR.
    Guan A, Dai Z, Jiang C, Sun J, Yang B, Xie B, Chen Q.

    09/26/2024
    Aryl hydrocarbon receptor (AhR) is regulated by hyperoxia in premature infants.

    Aryl hydrocarbon receptor (AhR) is regulated by hyperoxia in premature infants.
    Yang X, Wang X, Dong W.

    09/23/2024
    The Aryl Hydrocarbon Receptor Regulates Invasiveness and Motility in Acute Myeloid Leukemia Cells through Expressional Regulation of Non-Muscle Myosin Heavy Chain IIA.

    The Aryl Hydrocarbon Receptor Regulates Invasiveness and Motility in Acute Myeloid Leukemia Cells through Expressional Regulation of Non-Muscle Myosin Heavy Chain IIA.
    Chang F, Wang L, Kim Y, Kim M, Lee S, Lee SW., Free PMC Article

    09/18/2024
    Acute exercise activates the AHR in peripheral blood mononuclear cells in an intensity-dependent manner.

    Acute exercise activates the AHR in peripheral blood mononuclear cells in an intensity-dependent manner.
    Joisten N, Walzik D, Schenk A, Metcalfe AJ, Belen S, Schaaf K, Jacko D, Gehlert S, Spiliopoulou P, Garzinsky AM, Thevis M, Rappelt L, Donath L, Meuth SG, Bloch W, Zimmer P.

    09/10/2024
    [The involvement and underlying mechanism of the aryl hydrocarbon receptor (AhR) in the impairment of male mammalian fertility induced by environmental pollutants].

    [The involvement and underlying mechanism of the aryl hydrocarbon receptor (AhR) in the impairment of male mammalian fertility induced by environmental pollutants].
    Yang YB, Peng Z, Peng SL, Mei GQ, Cheng YM.

    09/9/2024
    The Aryl Hydrocarbon Receptor Regulates Epidermal Differentiation through Transient Activation of TFAP2A.

    The Aryl Hydrocarbon Receptor Regulates Epidermal Differentiation through Transient Activation of TFAP2A.
    Smits JPH, Qu J, Pardow F, van den Brink NJM, Rodijk-Olthuis D, van Vlijmen-Willems IMJJ, van Heeringen SJ, Zeeuwen PLJM, Schalkwijk J, Zhou H, van den Bogaard EH.

    08/29/2024
    Aryl hydrocarbon receptor impairs circadian regulation in Alzheimer's disease: Potential impact on glymphatic system dysfunction.

    Aryl hydrocarbon receptor impairs circadian regulation in Alzheimer's disease: Potential impact on glymphatic system dysfunction.
    Salminen A.

    08/6/2024
    Interferon subverts an AHR-JUN axis to promote CXCL13[+] T cells in lupus.

    Interferon subverts an AHR-JUN axis to promote CXCL13(+) T cells in lupus.
    Law C, Wacleche VS, Cao Y, Pillai A, Sowerby J, Hancock B, Horisberger A, Bracero S, Skidanova V, Li Z, Adejoorin I, Dillon E, Benque IJ, Nunez DP, Simmons DP, Keegan J, Chen L, Baker T, Brohawn PZ, Al-Mossawi H, Hao LY, Jones B, Rao N, Qu Y, Alves SE, Accelerating Medicines Partnership: RA/SLE Network, Jonsson AH, Shaw KS, Vleugels RA, Massarotti E, Costenbader KH, Brenner MB, Lederer JA, Hultquist JF, Choi J, Rao DA., Free PMC Article

    07/26/2024
    Mechanisms underlying aryl hydrocarbon receptor-driven divergent macrophage function.

    Mechanisms underlying aryl hydrocarbon receptor-driven divergent macrophage function.
    Malany K, Li X, Vogel CFA, Ehrlich AK.,

    07/1/2024
    Exploring aryl hydrocarbon receptor expression and distribution in the tumor microenvironment, with a focus on immune cells, in various solid cancer types.

    Exploring aryl hydrocarbon receptor expression and distribution in the tumor microenvironment, with a focus on immune cells, in various solid cancer types.
    Kim DK, Lee CY, Han YJ, Park SY, Han H, Na K, Kim MH, Yang SM, Baek S, Kim Y, Hwang JY, Lee S, Kang SS, Hong MH, Lim SM, Lee JB, Kim JH, Cho BC, Pyo KH., Free PMC Article

    05/23/2024
    AHR signaling pathway mediates mitochondrial oxidative phosphorylation which leads to cytarabine resistance.

    AHR signaling pathway mediates mitochondrial oxidative phosphorylation which leads to cytarabine resistance.
    Jia Y, Li X, Chen L, Li L, Zhang S, Huang W, Zhang H., Free PMC Article

    05/1/2024
    Targeting aryl hydrocarbon receptor to prevent cancer in barrier organs.

    Targeting aryl hydrocarbon receptor to prevent cancer in barrier organs.
    Congues F, Wang P, Lee J, Lin D, Shahid A, Xie J, Huang Y., Free PMC Article

    04/25/2024
    Association between estrogen receptor alpha and aryl hydrocarbon receptor gene polymorphisms in the prognosis of breast cancer in Egypt.

    Association between estrogen receptor alpha and aryl hydrocarbon receptor gene polymorphisms in the prognosis of breast cancer in Egypt.
    Aboelroos SA, Eltamany EHM, Mohamed FAM, Suliman MA.

    04/19/2024
    Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis.

    Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis.
    Gao L, Zhang W, Zhang L, Gromova B, Chen G, Csizmadia E, Cagle C, Nastasio S, Ma Y, Bonder A, Patwardhan V, Robson SC, Jiang S, Longhi MS.,

    04/3/2024
    hsa_circ_0008500 regulates Benzo(a)pyrene-loaded gypsum-induced inflammation and apoptosis in human bronchial epithelial cells via activation of Ahr/C-myc pathways.

    hsa_circ_0008500 regulates Benzo(a)pyrene-loaded gypsum-induced inflammation and apoptosis in human bronchial epithelial cells via activation of Ahr/C-myc pathways.
    Wang Y, Song J, He J, Zhang X, Lv Z, Dong F, Deng J.

    04/1/2024
    A microbially produced AhR ligand promotes a Tph1-driven tolerogenic program in multiple sclerosis.

    A microbially produced AhR ligand promotes a Tph1-driven tolerogenic program in multiple sclerosis.
    Zelante T, Paolicelli G, Fallarino F, Gargaro M, Vascelli G, De Zuani M, Fric J, Laznickova P, Kohoutkova MH, Macchiarulo A, Dolciami D, Pieraccini G, Gaetani L, Scalisi G, Trevisan C, Frossi B, Pucillo C, De Luca A, Nunzi E, Spaccapelo R, Pariano M, Borghi M, Boscaro F, Romoli R, Mancini A, Gentili L, Renga G, Costantini C, Puccetti M, Giovagnoli S, Ricci M, Antonini M, Calabresi P, Puccetti P, Di Filippo M, Romani L., Free PMC Article

    03/25/2024
    Aryl hydrocarbon receptor suppresses STING-mediated type I IFN expression in triple-negative breast cancer.

    Aryl hydrocarbon receptor suppresses STING-mediated type I IFN expression in triple-negative breast cancer.
    Martin JC, da Silva Fernandes T, Chaudhry KA, Oshi M, Abrams SI, Takabe K, Rosario SR, Bianchi-Smiraglia A., Free PMC Article

    03/13/2024
    Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance.

    Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance.
    Therachiyil L, Peerapen P, Younis SM, Ahmad A, Thongboonkerd V, Uddin S, Korashy HM.

    02/28/2024
    Pyrene and its derivatives increase lung adverse effects by activating aryl hydrocarbon receptor transcription.

    Pyrene and its derivatives increase lung adverse effects by activating aryl hydrocarbon receptor transcription.
    Wang M, Luo N, Gao Y, Li G, An T.

    02/28/2024
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