| A clinical study on sex hormone levels and CYP17-34T/C polymorphism in hypospadias or cryptorchidism. | A clinical study on sex hormone levels and CYP17-34T/C polymorphism in hypospadias or cryptorchidism.
Shu L, Yuan Z, He X, Han Z, Yang F, Xiao P, Chen L. | 09/16/2024 |
| Revealing a New Homozygous Variant in CYP17A1 c.908G>A (p. Gly303Asp) by Genotyping a Chinese Patient with 46, XY 17a-Hydroxylase/17,20-Lyase Deficiency and Adrenal Space-Occupying Lesion. | Revealing a New Homozygous Variant in CYP17A1 c.908G>A (p. Gly303Asp) by Genotyping a Chinese Patient with 46, XY 17a-Hydroxylase/17,20-Lyase Deficiency and Adrenal Space-Occupying Lesion.
Wang M, Hu X, Xu X, Chen H, Xue J. | 08/18/2024 |
| 17alpha Hydroxylase/17,20 lyase deficiency: clinical features and genetic insights from a large Turkey cohort. | 17α Hydroxylase/17,20 lyase deficiency: clinical features and genetic insights from a large Turkey cohort.
Siklar Z, Camtosun E, Bolu S, Yildiz M, Akinci A, Bas F, Dündar İ, Bestas A, Ünal E, Kocaay P, Guran T, Buyukyilmaz G, Ugurlu AK, Tosun BG, Turan I, Kurnaz E, Yuksel B, Turkkahraman D, Cayir A, Celmeli G, Gonc EN, Eklioğlu BS, Cetinkaya S, Yilmaz SK, Atabek ME, Buyukinan M, Arslan E, Mengen E, Cakir EDP, Karaoglan M, Hatipoglu N, Orbak Z, Ucar A, Akyurek N, Akbas ED, Isik E, Kaygusuz SB, Sutcu ZK, Seymen G, Berberoglu M., Free PMC Article | 08/12/2024 |
| Tracking protein-protein interactions by NMR: conformational selection in human steroidogenic cytochrome P450 CYP17A1 induced by cytochrome b5. | Tracking protein-protein interactions by NMR: conformational selection in human steroidogenic cytochrome P450 CYP17A1 induced by cytochrome b(5).
Richard AM, Estrada DF, Flynn L, Pochapsky SS, Scott EE, Pochapsky TC., Free PMC Article | 07/9/2024 |
| Proteomics, modeling, and fluorescence assays delineate cytochrome b5 residues involved in binding and stimulation of cytochrome P450 17A1 17,20-lyase. | Proteomics, modeling, and fluorescence assays delineate cytochrome b(5) residues involved in binding and stimulation of cytochrome P450 17A1 17,20-lyase.
Tateishi Y, Webb SN, Li B, Liu L, Lindsey Rose K, Leser M, Patel P, Guengerich FP., Free PMC Article | 04/5/2024 |
| Prostate cancer androgen biosynthesis relies solely on CYP17A1 downstream metabolites. | Prostate cancer androgen biosynthesis relies solely on CYP17A1 downstream metabolites.
Snaterse G, Taylor AE, Moll JM, O'Neil DM, Teubel WJ, van Weerden WM, Arlt W, Hofland J. | 01/15/2024 |
| CYP17A1 (rs74357) polymorphism and polycystic ovary syndrome risk: a systemic review and meta-analysis. | CYP17A1 (rs74357) polymorphism and polycystic ovary syndrome risk: a systemic review and meta-analysis.
Rezgoun ML, El Khour D, Bendaoud H, Chellat D., Free PMC Article | 08/7/2023 |
| Mutated CYP17A1 promotes atherosclerosis and early-onset coronary artery disease. | Mutated CYP17A1 promotes atherosclerosis and early-onset coronary artery disease.
Wu TT, Zheng YY, Ma X, Xiu WJ, Yang HT, Hou XG, Yang Y, Chen Y, Ma YT, Xie X., Free PMC Article | 06/30/2023 |
| Clinical characteristics and molecular etiology of partial 17alpha-hydroxylase deficiency diagnosed in 46,XX patients. | Clinical characteristics and molecular etiology of partial 17α-hydroxylase deficiency diagnosed in 46,XX patients.
Zhang D, Yao F, Luo M, Wang Y, Tian T, Deng S, Tian Q., Free PMC Article | 01/14/2023 |
| A Role of DNA Methylation within the CYP17A1 Gene in the Association of Genetic and Environmental Risk Factors with Stress-Related Manifestations of Schizophrenia. | A Role of DNA Methylation within the CYP17A1 Gene in the Association of Genetic and Environmental Risk Factors with Stress-Related Manifestations of Schizophrenia.
Alfimova M, Kondratyev N, Korovaitseva G, Lezheiko T, Plakunova V, Gabaeva M, Golimbet V., Free PMC Article | 11/5/2022 |
| Insights into Interactions of Human Cytochrome P450 17A1: A Review. | Insights into Interactions of Human Cytochrome P450 17A1: A Review.
Singh H, Kumar R, Mazumder A, Salahuddin, Mazumder R, Abdullah MM. | 08/6/2022 |
| Aberrant H19 Expression Disrupts Ovarian Cyp17 and Testosterone Production and Is Associated with Polycystic Ovary Syndrome in Women. | Aberrant H19 Expression Disrupts Ovarian Cyp17 and Testosterone Production and Is Associated with Polycystic Ovary Syndrome in Women.
Chen Z, Liu L, Xi X, Burn M, Karakaya C, Kallen AN., Free PMC Article | 04/30/2022 |
| Importance of Asparagine 202 in Manipulating Active Site Structure and Substrate Preference for Human CYP17A1. | Importance of Asparagine 202 in Manipulating Active Site Structure and Substrate Preference for Human CYP17A1.
Liu Y, Denisov I, Gregory M, Sligar SG, Kincaid JR., Free PMC Article | 04/16/2022 |
| A rare cause of delayed puberty and primary amenorrhea: 17alpha-hydroxylase enzyme deficiency. | A rare cause of delayed puberty and primary amenorrhea: 17α-hydroxylase enzyme deficiency.
Beştaş A, Bolu S, Unal E, Aktar Karakaya A, Eröz R, Tekin M, Haspolat YK. | 04/2/2022 |
| The single-nucleotide polymorphism rs743572 of CYP17A1 shows significant association with polycystic ovary syndrome: a meta-analysis. | The single-nucleotide polymorphism rs743572 of CYP17A1 shows significant association with polycystic ovary syndrome: a meta-analysis.
Xu X, Hu K, Shi H, Yu Y, Xu J, Sun Y. | 02/26/2022 |
| Novel mutations of the CYP17A1 gene in four Chinese 46,XX cases with partial 17a-hydroxylase/17,20-lyase deficiency. | Novel mutations of the CYP17A1 gene in four Chinese 46,XX cases with partial 17a-hydroxylase/17,20-lyase deficiency.
Xia Y, Shi P, Xia J, Zhang H, Xu L, Kong X. | 01/29/2022 |
| Association of the CYP17 and CYP19 gene polymorphisms in women with polycystic ovary syndrome from Punjab, Pakistan. | Association of the CYP17 and CYP19 gene polymorphisms in women with polycystic ovary syndrome from Punjab, Pakistan.
Munawar Lone N, Babar S, Sultan S, Malik S, Nazeer K, Riaz S. | 01/8/2022 |
| Mechanism of the Clinically Relevant E305G Mutation in Human P450 CYP17A1. | Mechanism of the Clinically Relevant E305G Mutation in Human P450 CYP17A1.
Liu Y, Grinkova Y, Gregory MC, Denisov IG, Kincaid JR, Sligar SG., Free PMC Article | 01/1/2022 |
| Stepwise binding of inhibitors to human cytochrome P450 17A1 and rapid kinetics of inhibition of androgen biosynthesis. | Stepwise binding of inhibitors to human cytochrome P450 17A1 and rapid kinetics of inhibition of androgen biosynthesis.
Guengerich FP, McCarty KD, Chapman JG, Tateishi Y., Free PMC Article | 12/4/2021 |
| Steroidogenic cytochrome P450 17A1 structure and function. | Steroidogenic cytochrome P450 17A1 structure and function.
Burris-Hiday SD, Scott EE., Free PMC Article | 12/4/2021 |
| CYP17 gene polymorphic sequence variation is associated with hyperandrogenism in Kashmiri women with polycystic ovarian syndrome. | CYP17 gene polymorphic sequence variation is associated with hyperandrogenism in Kashmiri women with polycystic ovarian syndrome.
Ashraf S, Rasool SUA, Nabi M, Ganie MA, Jabeen F, Rashid F, Amin S. | 11/22/2021 |
| Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 subjects. | Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 subjects.
Hou B, Jia X, Deng Z, Liu X, Liu H, Yu H, Liu S., Free PMC Article | 10/23/2021 |
| Polymorphism in the Androgen Biosynthesis Gene (CYP17), a Risk for Prostate Cancer: A Meta-Analysis. | Polymorphism in the Androgen Biosynthesis Gene (CYP17), a Risk for Prostate Cancer: A Meta-Analysis.
Effah CY, Wang L, Agboyibor C, Drokow EK, Yu S, Wang W, Wu Y., Free PMC Article | 10/23/2021 |
| [Clinical characteristics and CYP17A1 gene mutation analysis in patients with 17alpha-hydroxylase/17, 20-lyase deficiency and testicular tumor]. | [Clinical characteristics and CYP17A1 gene mutation analysis in patients with 17α-hydroxylase/17, 20-lyase deficiency and testicular tumor].
Han BB, Zheng RZ, Xie YD, Chen YQ, Niu JP, Zhang Y. | 09/25/2021 |
| Relationship between CYP17A1-Mediated DNA Demethylation and Proliferation, Invasion and Metastasis of Glioma Cells. | Relationship between CYP17A1-Mediated DNA Demethylation and Proliferation, Invasion and Metastasis of Glioma Cells.
Meng L, Lv W, Zhou Y. | 08/28/2021 |