| Expanding Our Knowledge of Molecular Pathogenesis in Histiocytoses: Solitary Soft Tissue Histiocytomas in Children With a Novel CLTC::SYK Fusion. | Expanding Our Knowledge of Molecular Pathogenesis in Histiocytoses: Solitary Soft Tissue Histiocytomas in Children With a Novel CLTC::SYK Fusion.
Crowley HM, Georgantzoglou N, Tse JY, Williams EA, Mata DA, Martin SS, Guitart J, Bridge JA, Linos K. | 09/21/2023 |
| Knockout of CLTC gene reduces but not completely block SFTSV infection. | Knockout of CLTC gene reduces but not completely block SFTSV infection.
Liu T, Li J, Wang X, Huang T, Wu W, Li A, Li C, Huang X, Wang Q, Li D, Wang S, Liang M., Free PMC Article | 08/30/2023 |
| Molecular investigation of ALK-rearranged epithelioid fibrous histiocytomas identifies CLTC as a novel fusion partner and evidence of fusion-independent transcription activation. | Molecular investigation of ALK-rearranged epithelioid fibrous histiocytomas identifies CLTC as a novel fusion partner and evidence of fusion-independent transcription activation.
Georgantzoglou N, Green D, Winnick KN, Sumegi J, Charville GW, Bridge JA, Linos K. | 06/18/2022 |
| Novel CLTC variants cause new brain and kidney phenotypes. | Novel CLTC variants cause new brain and kidney phenotypes.
Itai T, Miyatake S, Tsuchida N, Saida K, Narahara S, Tsuyusaki Y, Castro MAA, Kim CA, Okamoto N, Uchiyama Y, Koshimizu E, Hamanaka K, Fujita A, Mizuguchi T, Matsumoto N. | 05/21/2022 |
| Deregulation of CLTC interacts with TFG, facilitating osteosarcoma via the TGF-beta and AKT/mTOR signaling pathways. | Deregulation of CLTC interacts with TFG, facilitating osteosarcoma via the TGF-beta and AKT/mTOR signaling pathways.
Shijie L, Zhen P, Kang Q, Hua G, Qingcheng Y, Dongdong C., Free PMC Article | 02/12/2022 |
| Clathrin: the molecular shape shifter. | Clathrin: the molecular shape shifter.
Wood KM, Smith CJ. | 12/4/2021 |
| SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis. | SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis.
Bayati A, Kumar R, Francis V, McPherson PS., Free PMC Article | 07/17/2021 |
| De novo CLTC variants are associated with a variable phenotype from mild to severe intellectual disability, microcephaly, hypoplasia of the corpus callosum, and epilepsy. | De novo CLTC variants are associated with a variable phenotype from mild to severe intellectual disability, microcephaly, hypoplasia of the corpus callosum, and epilepsy.
Nabais Sá MJ, Venselaar H, Wiel L, Trimouille A, Lasseaux E, Naudion S, Lacombe D, Piton A, Vincent-Delorme C, Zweier C, Reis A, Trollmann R, Ruiz A, Gabau E, Vetro A, Guerrini R, Bakhtiari S, Kruer MC, Amor DJ, Cooper MS, Bijlsma EK, Barakat TS, van Dooren MF, van Slegtenhorst M, Pfundt R, Gilissen C, Willemsen MA, de Vries BBA, de Brouwer APM, Koolen DA. | 06/26/2021 |
| Clathrin switches transforming growth factor-beta role to pro-tumorigenic in liver cancer. | Clathrin switches transforming growth factor-β role to pro-tumorigenic in liver cancer.
Caballero-Díaz D, Bertran E, Peñuelas-Haro I, Moreno-Càceres J, Malfettone A, López-Luque J, Addante A, Herrera B, Sánchez A, Alay A, Solé X, Serrano T, Ramos E, Fabregat I. | 06/5/2021 |
| Pluripotency of embryonic stem cells lacking clathrin-mediated endocytosis cannot be rescued by restoring cellular stiffness. | Pluripotency of embryonic stem cells lacking clathrin-mediated endocytosis cannot be rescued by restoring cellular stiffness.
Mote RD, Yadav J, Singh SB, Tiwari M, V SL, Patil S, Subramanyam D., Free PMC Article | 05/8/2021 |
| This investigation provides a functional link between CLTC and autophagy in the context of Coxiella infection. | Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain).
Latomanski EA, Newton HJ., Free PMC Article | 10/5/2019 |
| Findings indicate that targeting the mitotic CHC complex can selectively induce apoptosis. | Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.
Bond MJ, Bleiler M, Harrison LE, Scocchera EW, Nakanishi M, G-Dayanan N, Keshipeddy S, Rosenberg DW, Wright DL, Giardina C., Free PMC Article | 08/31/2019 |
| Provide biochemical evidence for separate regulation and distinct functional niches for CHC17 and CHC22 in HeLa cells. Furthermore, the greater stability of the CHC22 coat relative to the CHC17 coat may be relevant to its excessive accumulation with GLUT4 during insulin resistance. | CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.
Dannhauser PN, Camus SM, Sakamoto K, Sadacca LA, Torres JA, Camus MD, Briant K, Vassilopoulos S, Rothnie A, Smith CJ, Brodsky FM., Free PMC Article | 12/22/2018 |
| this study shows that clathrin, including the clathrin population associated to internal vesicles, controls lymphocyte migration by regulating actin rearrangements occurring at the leading age | Clathrin regulates lymphocyte migration by driving actin accumulation at the cellular leading edge.
Ramírez-Santiago G, Robles-Valero J, Morlino G, Cruz-Adalia A, Pérez-Martínez M, Zaldivar A, Torres-Torresano M, Chichón FJ, Sorrentino A, Pereiro E, Carrascosa JL, Megías D, Sorzano CO, Sánchez-Madrid F, Veiga E., Free PMC Article | 07/1/2017 |
| The novel association of several endocytosis-associated proteins has been demonstrated, in particular, of CLTC and SCAMP3 with hepatocellular carcinoma progression. | Quantitative proteome analysis reveals the correlation between endocytosis-associated proteins and hepatocellular carcinoma dedifferentiation.
Naboulsi W, Bracht T, Megger DA, Reis H, Ahrens M, Turewicz M, Eisenacher M, Tautges S, Canbay AE, Meyer HE, Weber F, Baba HA, Sitek B. | 06/3/2017 |
| MiR-199a-5p suppresses tumorigenesis by targeting CLTC in hepatocellular carcinoma. | MiR-199a-5p suppresses tumorigenesis by targeting clathrin heavy chain in hepatocellular carcinoma.
Huang GH, Shan H, Li D, Zhou B, Pang PF. | 03/18/2017 |
| Data indicate that clathrin-mediated endocytosis of proto-oncogene protein erbB-3 (ErbB3) is depending on epsin-1. | Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3.
Szymanska M, Fosdahl AM, Raiborg C, Dietrich M, Liestøl K, Stang E, Bertelsen V. | 07/30/2016 |
| SMAP2 immunoprecipitated clathrin and AP-1 through a putative clathrin-binding domain and a CALM-binding domain, and SMAP2 mutants that did not interact with clathrin or AP-1 could not localize to recycling endosomes | Transport of the cholera toxin B-subunit from recycling endosomes to the Golgi requires clathrin and AP-1.
Matsudaira T, Niki T, Taguchi T, Arai H. | 06/4/2016 |
| The CHC:ESR1 interaction is required to sustain estradiol signaling. | Clathrin Heavy Chain Interacts With Estrogen Receptor α and Modulates 17β-Estradiol Signaling.
Totta P, Pesiri V, Enari M, Marino M, Acconcia F., Free PMC Article | 04/2/2016 |
| autophagy contributed to Cx31.1 degradation, and clathrin might be involved in the autophagy of Cx31.1. | Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.
Zhu X, Ruan Z, Yang X, Chu K, Wu H, Li Y, Huang Y., Free PMC Article | 09/5/2015 |
| Data suggest that by binding to both clathrin and F-actin, mammalian actin-binding protein 1 (mAbp1; HIP-55 or SH3P7) is specifically recruited at a late stage of clathrin-coated pits (CCPs) formation, which subsequently recruits dynamin to CCPs. | Mammalian actin-binding protein 1/HIP-55 is essential for the scission of clathrin-coated pits by regulating dynamin-actin interaction.
He K, Xing R, Yan X, Tian A, Zhang M, Yuan J, Lv Z, Fang X, Li Z, Zhang Y. | 08/29/2015 |
| In conclusion these data suggest that Streptococcus pneumoniae PspC-promoted uptake via the polymeric immunoglobulin receptor of epithelial cells is mediated by both clathrin and caveolin dependent pathway. | Endocytosis of Streptococcus pneumoniae via the polymeric immunoglobulin receptor of epithelial cells relies on clathrin and caveolin dependent mechanisms.
Asmat TM, Agarwal V, Saleh M, Hammerschmidt S. | 07/25/2015 |
| Our data support a model in which nascent Hepatits C Virus particles associate with apoE in the endoplasmic reticulum and exit cells following a clathrin-dependent transendosomal secretory route. | Clathrin mediates infectious hepatitis C virus particle egress.
Benedicto I, Gondar V, Molina-Jiménez F, García-Buey L, López-Cabrera M, Gastaminza P, Majano PL., Free PMC Article | 05/30/2015 |
| clathrin-mediated and caveolae-mediated endocytosis of VE-cad contribute to lipopolysaccharide-induced vascular hyperpermeability. | Different contributions of clathrin- and caveolae-mediated endocytosis of vascular endothelial cadherin to lipopolysaccharide-induced vascular hyperpermeability.
Zhang Y, Zhang L, Li Y, Sun S, Tan H., Free PMC Article | 05/30/2015 |
| These data indicate that clathrin is required for the function of AP-1- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane. | Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors.
Stahlschmidt W, Robertson MJ, Robinson PJ, McCluskey A, Haucke V., Free PMC Article | 04/26/2014 |