| NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation. | NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation.
Shen NX, Qu XC, Yu J, Fan CX, Min FL, Li LY, Zhang MR, Li BM, Wang J, He N, Liao WP, Shi YW, Li WB. | 10/30/2024 |
| Novel NUS1 variant in a Chinese patient with progressive myoclonus epilepsy: a case report and systematic review. | Novel NUS1 variant in a Chinese patient with progressive myoclonus epilepsy: a case report and systematic review.
Ji C, Zhao J, Zhang J, Wang K. | 09/26/2023 |
| Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1alpha-dependent pathway. | Nogo-B receptor increases glycolysis and the paclitaxel resistance of estrogen receptor-positive breast cancer via the HIF-1α-dependent pathway.
Liu C, Li S, Zhang X, Jin C, Zhao B, Li L, Miao QR, Jin Y, Fan Z. | 05/19/2023 |
| Low-frequency and rare coding variants of NUS1 contribute to susceptibility and phenotype of Parkinson's disease. | Low-frequency and rare coding variants of NUS1 contribute to susceptibility and phenotype of Parkinson's disease.
Jiang L, Mei JP, Zhao YW, Zhang R, Pan HX, Yang Y, Sun QY, Xu Q, Yan XX, Tan JQ, Li JC, Tang BS, Guo JF. | 02/19/2022 |
| Common Variants in NUS1 and GP2 Genes Contributed to the Risk of Gestational Diabetes Mellitus. | Common Variants in NUS1 and GP2 Genes Contributed to the Risk of Gestational Diabetes Mellitus.
Zhang T, Zhao L, Wang S, Liu J, Chang Y, Ma L, Feng J, Niu Y., Free PMC Article | 01/15/2022 |
| Contribution of coding/non-coding variants in NUS1 to late-onset sporadic Parkinson's disease. | Contribution of coding/non-coding variants in NUS1 to late-onset sporadic Parkinson's disease.
Jiang L, Pan HX, Zhao YW, Zeng Q, Liu ZH, Sun QY, Xu Q, Tan JQ, Yan XX, Li JC, Tang BS, Guo JF. | 01/1/2022 |
| NUS1 mutation in a family with epilepsy, cerebellar ataxia, and tremor. | NUS1 mutation in a family with epilepsy, cerebellar ataxia, and tremor.
Araki K, Nakamura R, Ito D, Kato K, Iguchi Y, Sahashi K, Toyama M, Hamada K, Okamoto N, Wada Y, Nakamura T, Ogi T, Katsuno M. | 12/25/2021 |
| Replication assessment of NUS1 variants in Parkinson's disease. | Replication assessment of NUS1 variants in Parkinson's disease.
Bustos BI, Bandres-Ciga S, Gibbs JR, Krainc D, Mencacci NE, Gan-Or Z, Lubbe SJ, International Parkinson's Disease Genomics Consortium (IPDGC)., Free PMC Article | 12/4/2021 |
| Salivary NUS1 and RCN1 Levels as Biomarkers for Oral Squamous Cell Carcinoma Diagnosis. | Salivary NUS1 and RCN1 Levels as Biomarkers for Oral Squamous Cell Carcinoma Diagnosis.
Ueda S, Hashimoto K, Miyabe S, Hasegawa S, Goto M, Shimizu D, Oh-Iwa I, Shimozato K, Nagao T, Nomoto S., Free PMC Article | 07/3/2021 |
| NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma. | NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.
Hu W, Liu Z, Salato V, North PE, Bischoff J, Kumar SN, Fang Z, Rajan S, Hussain MM, Miao QR., Free PMC Article | 05/29/2021 |
| Assessment of the association between NUS1 variants and essential tremor. | Assessment of the association between NUS1 variants and essential tremor.
Yang HL, Jiang L, Pan HX, Xu K, Zhao YW, Liu ZH, Xu Q, Sun QY, Tan JQ, Li JC, Tang BS, Guo JF. | 05/8/2021 |
| Nogo-B fosters HCC progression by enhancing Yap/Taz-mediated tumor-associated macrophages M2 polarization. | Nogo-B fosters HCC progression by enhancing Yap/Taz-mediated tumor-associated macrophages M2 polarization.
Zhao X, Wang X, You Y, Wen D, Feng Z, Zhou Y, Que K, Gong J, Liu Z. | 12/12/2020 |
| Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex. | Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex.
Bar-El ML, Vaňková P, Yeheskel A, Simhaev L, Engel H, Man P, Haitin Y, Giladi M., Free PMC Article | 11/21/2020 |
| Structural elucidation of the cis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation. | Structural elucidation of the cis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation.
Edani BH, Grabińska KA, Zhang R, Park EJ, Siciliano B, Surmacz L, Ha Y, Sessa WC., Free PMC Article | 10/31/2020 |
| we report two unrelated Japanese patients with a novel, recurrent, de novo NUS1 variant, who presented with epileptic seizures with involuntary movement, ataxia, intellectual disability and scoliosis. | Recurrent NUS1 canonical splice donor site mutation in two unrelated individuals with epilepsy, myoclonus, ataxia and scoliosis - a case report.
Den K, Kudo Y, Kato M, Watanabe K, Doi H, Tanaka F, Oguni H, Miyatake S, Mizuguchi T, Takata A, Miyake N, Mitsuhashi S, Matsumoto N., Free PMC Article | 01/11/2020 |
| NUS1 was upregulated in IUAs tissues, and the high expression level of NUS1 was positively correlated with the severity of IUAs. NUS1 promoted cell proliferation in vitro. NUS1 overexpression on cell migration and invasion promoted the EMT process in vitro and in vivo. | miR-466 and NUS1 Regulate the AKT/Nuclear Factor kappa B (NFκB) Signaling Pathway in Intrauterine Adhesions in a Rat Model.
Liu M, Zhao D, Wu X, Guo S, Yan L, Zhao S, Li H, Wang Y, Rong F., Free PMC Article | 12/14/2019 |
| The Nogo-B receptor was highly expressed in human hepatocellular carcinoma (HCC) cell lines and in the tissue of patients with HCC and promoted human HCC cell growth by increasing the Akt phosphorylation in human HCC cells | The Nogo-B receptor promotes human hepatocellular carcinoma cell growth via the Akt signal pathway.
Dong C, Liu Y, Jiang K, Wang H, Qu W, Zhang C, Liang R, Gao Z, Zhao B, Miao Q, Shao S, Wang L., Free PMC Article | 10/12/2019 |
| Results suggest that Nogo-B receptor (NgBR) is a potential therapeutic target for increasing the sensitivity of estrogen receptor alpha (ERalpha)-positive breast cancer to tamoxifen. | Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells.
Gao P, Wang X, Jin Y, Hu W, Duan Y, Shi A, Du Y, Song D, Yang M, Li S, Han B, Zhao G, Zhang H, Fan Z, Miao QR., Free PMC Article | 06/1/2019 |
| Coding mutations in NUS1 contribute to Parkinson's disease. | Coding mutations in NUS1 contribute to Parkinson's disease.
Guo JF, Zhang L, Li K, Mei JP, Xue J, Chen J, Tang X, Shen L, Jiang H, Chen C, Guo H, Wu XL, Sun SL, Xu Q, Sun QY, Chan P, Shang HF, Wang T, Zhao GH, Liu JY, Xie XF, Jiang YQ, Liu ZH, Zhao YW, Zhu ZB, Li JD, Hu ZM, Yan XX, Fang XD, Wang GH, Zhang FY, Xia K, Liu CY, Zhu XW, Yue ZY, Li SC, Cai HB, Zhang ZH, Duan RH, Tang BS., Free PMC Article | 05/4/2019 |
| NgBR role in cancer.NgBR is able to promote N-glycosylation to attenuate endoplasmic reticulum stress and the unfolded protein response.[review] | Nogo‑B receptor in relevant carcinoma: Current achievements, challenges and aims (Review).
Li YK, Xie YJ, Wu DC, Long SL, Tang S, Mo ZC. | 03/30/2019 |
| Data show that Nogo-B receptor (NgBR) knockdown inhibited epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) cells in vitro and metastasis of NSCLC cells in vivo. | Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, Miao QR, Shao S., Free PMC Article | 02/2/2019 |
| Data suggest that Nogo-B receptor (NgBR) expression is essential to promoting estrogen receptor alpha (ERalpha) positive breast cancer cell resistance to paclitaxel. | Nogo-B receptor increases the resistance of estrogen receptor positive breast cancer to paclitaxel.
Jin Y, Hu W, Liu T, Rana U, Aguilera-Barrantes I, Kong A, Kumar SN, Wang B, Gao P, Wang X, Duan Y, Shi A, Song D, Yang M, Li S, Han B, Zhao G, Fan Z, Miao QR., Free PMC Article | 02/2/2019 |
| The data suggest that miR-26a plays a key role in VEGF-mediated angiogenesis through the modulation of eNOS activity, which is mediated by its ability to regulate NgBR expression by directly targeting the NgBR 3'-UTR. | Endothelial miR-26a regulates VEGF-Nogo-B receptor-mediated angiogenesis.
Jo HN, Kang H, Lee A, Choi J, Chang W, Lee MS, Kim J., Free PMC Article | 03/17/2018 |
| Small Angle X-ray Scattering (SAXS) analysis reveals the radius of gyration (Rg) of our NgBR construct to be 18.2 A with a maximum particle dimension (Dmax) of 61.0 A. Ab initio shape modeling returns a globular molecular envelope with an estimated molecular weight of 23.0 kD closely correlated with the calculated molecular weight | SAXS analysis of a soluble cytosolic NgBR construct including extracellular and transmembrane domains.
Holcomb J, Doughan M, Spellmon N, Lewis B, Perry E, Zhang Y, Nico L, Wan J, Chakravarthy S, Shang W, Miao Q, Stemmler T, Yang Z., Free PMC Article | 03/10/2018 |
| findings show that eukaryotic cis-PT is composed of the NgBR and hCIT subunits. The strong conservation of the RXG motif among NgBR orthologs indicates that this subunit is critical for the synthesis of polyprenol diphosphates and cellular function. | A conserved C-terminal RXG motif in the NgBR subunit of cis-prenyltransferase is critical for prenyltransferase activity.
Grabińska KA, Edani BH, Park EJ, Kraehling JR, Sessa WC., Free PMC Article | 10/28/2017 |