| KDELR2 is necessary for chronic obstructive pulmonary disease airway Mucin5AC hypersecretion via an IRE1alpha/XBP-1s-dependent mechanism. | KDELR2 is necessary for chronic obstructive pulmonary disease airway Mucin5AC hypersecretion via an IRE1α/XBP-1s-dependent mechanism.
Wu X, Du F, Zhang A, Zhang G, Xu R, Du X., Free PMC Article | 10/18/2024 |
| Two novel bi-allelic KDELR2 missense variants cause osteogenesis imperfecta with neurodevelopmental features. | Two novel bi-allelic KDELR2 missense variants cause osteogenesis imperfecta with neurodevelopmental features.
Efthymiou S, Herman I, Rahman F, Anwar N, Maroofian R, Yip J, Mitani T, Calame DG, Hunter JV, Sutton VR, Yilmaz Gulec E, Duan R, Fatih JM, Marafi D, Pehlivan D, Jhangiani SN, Gibbs RA, Posey JE, SYNAPS Study Group, Maqbool S, Lupski JR, Houlden H., Free PMC Article | 01/1/2022 |
| KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression. | KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.
Wei H, Ma W, Lu X, Liu H, Lin K, Wang Y, Ye Z, Sun L, Huang Z, Pan T, Zhou Z, Cheng EY, Zhang H, Gao P, Zhong X., Free PMC Article | 10/23/2021 |
| KDELR2 is an unfavorable prognostic biomarker and regulates CCND1 to promote tumor progression in glioma. | KDELR2 is an unfavorable prognostic biomarker and regulates CCND1 to promote tumor progression in glioma.
Mao H, Nian J, Wang Z, Li X, Huang C. | 04/3/2021 |
| Interaction between KDELR2 and HSP47 as a Key Determinant in Osteogenesis Imperfecta Caused by Bi-allelic Variants in KDELR2. | Interaction between KDELR2 and HSP47 as a Key Determinant in Osteogenesis Imperfecta Caused by Bi-allelic Variants in KDELR2.
van Dijk FS, Semler O, Etich J, Köhler A, Jimenez-Estrada JA, Bravenboer N, Claeys L, Riesebos E, Gegic S, Piersma SR, Jimenez CR, Waisfisz Q, Flores CL, Nevado J, Harsevoort AJ, Janus GJM, Franken AAM, van der Sar AM, Meijers-Heijboer H, Heath KE, Lapunzina P, Nikkels PGJ, Santen GWE, Nüchel J, Plomann M, Wagener R, Rehberg M, Hoyer-Kuhn H, Eekhoff EMW, Pals G, Mörgelin M, Newstead S, Wilson BT, Ruiz-Perez VL, Maugeri A, Netzer C, Zaucke F, Micha D., Free PMC Article | 12/12/2020 |
| Cell-type-specific differences in KDEL receptor clustering in mammalian cells. | Cell-type-specific differences in KDEL receptor clustering in mammalian cells.
Bauer A, Santen L, Schmitt MJ, Shaebani MR, Becker B., Free PMC Article | 10/3/2020 |
| KDELR2 is a target gene downstream of HIF1-alpha driving the malignancy of glioblastoma. | KDELR2 Promotes Glioblastoma Tumorigenesis Targeted by HIF1a via mTOR Signaling Pathway.
Liao Z, She C, Ma L, Sun Z, Li P, Zhang X, Wang P, Li W. | 01/25/2020 |
| Our data indicate that KDELR2 competes with measles virus (MV) envelope proteins for binding to calnexin and GRP78/Bip, and that this interaction limits the availability of the chaperones for MV proteins, causing the reduction of virus spread and titers. | KDELR2 Competes with Measles Virus Envelope Proteins for Cellular Chaperones Reducing Their Chaperone-Mediated Cell Surface Transport.
Tiwarekar V, Fehrholz M, Schneider-Schaulies J., Free PMC Article | 05/18/2019 |
| show that Golgi-based, KDEL receptor-dependent signalling promotes lysosome repositioning to the perinuclear area, involving a complex process intertwined to autophagy, lipid-droplet turnover and Golgi-mediated secretion. | KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover.
Tapia D, Jiménez T, Zamora C, Espinoza J, Rizzo R, González-Cárdenas A, Fuentes D, Hernández S, Cavieres VA, Soza A, Guzmán F, Arriagada G, Yuseff MI, Mardones GA, Burgos PV, Luini A, González A, Cancino J., Free PMC Article | 04/13/2019 |
| A Golgi-based KDELR-dependent signalling pathway controls invadopodia-dependent extracellular matrix degradation. | A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation.
Ruggiero C, Fragassi G, Grossi M, Picciani B, Di Martino R, Capitani M, Buccione R, Luini A, Sallese M., Free PMC Article | 04/2/2016 |
| Hrr25 protein kinase directly modifies Elp1 on two sites and we provide evidence that phosphorylation plays a positive role in the tRNA modification | Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.
Abdel-Fattah W, Jablonowski D, Di Santo R, Thüring KL, Scheidt V, Hammermeister A, Ten Have S, Helm M, Schaffrath R, Stark MJ., Free PMC Article | 07/4/2015 |