CENPF Upregulation is Associated with Immunosuppressive Status and Poor Clinical Outcomes in Lung Adenocarcinoma Validated by qRT-PCR. | CENPF Upregulation is Associated with Immunosuppressive Status and Poor Clinical Outcomes in Lung Adenocarcinoma Validated by qRT-PCR. Xu Z, Xu D, You Z, Tian W. | 01/17/2024 |
Novel Loss of Function Variants in CENPF Including a Large Intragenic Deletion in Patients with Stromme Syndrome. | Novel Loss of Function Variants in CENPF Including a Large Intragenic Deletion in Patients with Strømme Syndrome. Misceo D, Senaratne LDS, Mero IL, Sundaram AYM, Bjørnstad PM, Szczałuba K, Gasperowicz P, Kamien B, Nedregaard B, Holmgren A, Strømme P, Frengen E., Free PMC Article | 11/28/2023 |
[Heterogeneity analysis of pancreatic cancer and identification of molecular subtypes of tumor cells based on CEACAM5, LGALS1 and CENPF gene expression]. | [Heterogeneity analysis of pancreatic cancer and identification of molecular subtypes of tumor cells based on CEACAM5, LGALS1 and CENPF gene expression]. Sun J, Lu P, Guan S, Liu S., Free PMC Article | 11/2/2023 |
Long Non-Coding RNA Small Nucleolar RNA Host Gene 4 Induced by Transcription Factor SP1 Promoted the Progression of Nasopharyngeal Carcinoma Through Modulating microRNA-510-5p/Centromere Protein F Axis. | Long Non-Coding RNA Small Nucleolar RNA Host Gene 4 Induced by Transcription Factor SP1 Promoted the Progression of Nasopharyngeal Carcinoma Through Modulating microRNA-510-5p/Centromere Protein F Axis. Zhou S, Cao C, Hu J. | 09/25/2023 |
Integrated pan-cancer analysis of centromere protein F and experimental verification of its role and clinical significance in cholangiocarcinoma. | Integrated pan-cancer analysis of centromere protein F and experimental verification of its role and clinical significance in cholangiocarcinoma. Cao Z, Zeng L, Wang Z, Wen X, Zhang J. | 06/2/2023 |
CENPF knockdown inhibits adriamycin chemoresistance in triple-negative breast cancer via the Rb-E2F1 axis. | CENPF knockdown inhibits adriamycin chemoresistance in triple-negative breast cancer via the Rb-E2F1 axis. Wang D, Xu W, Huang M, Ma W, Liu Y, Zhou X, Yang Q, Mu K., Free PMC Article | 02/4/2023 |
Hsa_circ_0002082 up-regulates Centromere Protein F via abolishing miR-508-3p to promote breast cancer progression. | Hsa_circ_0002082 up-regulates Centromere Protein F via abolishing miR-508-3p to promote breast cancer progression. Liu Y, Liu Y, Luo J, Zhao W, Hu C, Chen G., Free PMC Article | 12/3/2022 |
Biallelic variants in CENPF causing a phenotype distinct from Stromme syndrome. | Biallelic variants in CENPF causing a phenotype distinct from Strømme syndrome. Cappuccio G, Brillante S, Tammaro R, Pinelli M, De Bernardi ML, Gensini MG, Bijlsma EK, Koopmann TT, Hoffer MJV, McDonald K, Hendon LG, Douzgou S, Deshpande C, D'Arrigo S, Torella A, Nigro V, Franco B, Brunetti-Pierri N., Free PMC Article | 07/30/2022 |
Centromere protein F promotes progression of hepatocellular carcinoma through ERK and cell cycle-associated pathways. | Centromere protein F promotes progression of hepatocellular carcinoma through ERK and cell cycle-associated pathways. Chen H, Wu F, Xu H, Wei G, Ding M, Xu F, Deivasigamani A, Zhou G, Hui KM, Xia H. | 07/23/2022 |
CENPF/CDK1 signaling pathway enhances the progression of adrenocortical carcinoma by regulating the G2/M-phase cell cycle. | CENPF/CDK1 signaling pathway enhances the progression of adrenocortical carcinoma by regulating the G2/M-phase cell cycle. Huang YG, Li D, Wang L, Su XM, Tang XB., Free PMC Article | 07/9/2022 |
CENPF as an independent prognostic and metastasis biomarker corresponding to CD4+ memory T cells in cutaneous melanoma. | CENPF as an independent prognostic and metastasis biomarker corresponding to CD4+ memory T cells in cutaneous melanoma. Li M, Zhao J, Yang R, Cai R, Liu X, Xie J, Shu B, Qi S., Free PMC Article | 04/16/2022 |
MiR-1-3p targets CENPF to repress tumor-relevant functions of gastric cancer cells. | MiR-1-3p targets CENPF to repress tumor-relevant functions of gastric cancer cells. Zhou S, Han H, Yang L, Lin H., Free PMC Article | 04/2/2022 |
Centromere protein F is identified as a novel therapeutic target by genomics profile and contributing to the progression of pancreatic cancer. | Centromere protein F is identified as a novel therapeutic target by genomics profile and contributing to the progression of pancreatic cancer. Chen H, Wang X, Wu F, Mo X, Hu C, Wang M, Xu H, Yao C, Xia H, Lan L. | 02/26/2022 |
miR-383-5p inhibits human malignant melanoma cells function via targeting CENPF. | miR-383-5p inhibits human malignant melanoma cells function via targeting CENPF. Xu H, Zhu X, Shi L, Lin N, Li X. | 01/15/2022 |
Overexpression of CENPF is associated with progression and poor prognosis of lung adenocarcinoma. | Overexpression of CENPF is associated with progression and poor prognosis of lung adenocarcinoma. Li MX, Zhang MY, Dong HH, Li AJ, Teng HF, Liu AL, Xu N, Qu YQ., Free PMC Article | 09/18/2021 |
TOP2A and CENPF are synergistic master regulators activated in cervical cancer. | TOP2A and CENPF are synergistic master regulators activated in cervical cancer. Yu B, Chen L, Zhang W, Li Y, Zhang Y, Gao Y, Teng X, Zou L, Wang Q, Jia H, Liu X, Zheng H, Hou P, Yu H, Sun Y, Zhang Z, Zhang P, Zhang L., Free PMC Article | 05/15/2021 |
LncRNA MCM3AP-AS1 promotes breast cancer progression via modulating miR-28-5p/CENPF axis. | LncRNA MCM3AP-AS1 promotes breast cancer progression via modulating miR-28-5p/CENPF axis. Chen Q, Xu H, Zhu J, Feng K, Hu C. | 02/27/2021 |
CENP-F stabilizes kinetochore-microtubule attachments and limits dynein stripping of corona cargoes. | CENP-F stabilizes kinetochore-microtubule attachments and limits dynein stripping of corona cargoes. Auckland P, Roscioli E, Coker HLE, McAinsh AD., Free PMC Article | 02/20/2021 |
Expanding the phenotype and the genotype of Stromme syndrome: A novel variant of the CENPF gene and literature review. | Expanding the phenotype and the genotype of Stromme syndrome: A novel variant of the CENPF gene and literature review. Alghamdi M, Alkhamis WH, Bashiri FA, Jamjoom D, Al-Nafisah G, Tahir A, Abdouelhoda M. | 01/2/2021 |
HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis. | HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis. Chen EB, Qin X, Peng K, Li Q, Tang C, Wei YC, Yu S, Gan L, Liu TS., Free PMC Article | 09/12/2020 |
CENPF was identified as a highly prognostic marker for nonmuscle invasive bladder cancer disease progression | Weighted gene coexpression network analysis identifies a new biomarker of CENPF for prediction disease prognosis and progression in nonmuscle invasive bladder cancer. Shi J, Zhang P, Liu L, Min X, Xiao Y., Free PMC Article | 07/4/2020 |
This study focuses on discerning the role of CENPF in metabolic perturbation in human PC3 cells. Silencing of CENPF alters the global metabolic profiles of prostate cancer and inhibits cell proliferation, which suggests that CENPF may be a critical regulator of prostate cancer metabolism. | Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism. Shahid M, Kim M, Lee MY, Yeon A, You S, Kim HL, Kim J., Free PMC Article | 05/2/2020 |
Silencing of CENPF also simultaneously improved sensitivity to anoikis-induced apoptosis. CENPF(KO) cells had reduced global bio-energetic capacity, acetyl-CoA production, histone acetylation, and lipid metabolism, suggesting that CENPF is a critical regulator of cancer metabolism, potentially through its effects on mitochondrial functioning. | Centromere protein F (CENPF), a microtubule binding protein, modulates cancer metabolism by regulating pyruvate kinase M2 phosphorylation signaling. Shahid M, Lee MY, Piplani H, Andres AM, Zhou B, Yeon A, Kim M, Kim HL, Kim J., Free PMC Article | 11/16/2019 |
Data demonstrate a direct association between rs7289, a CENP-F single nucleotide polymorphism and heart failure patients with reduced ejection fraction. | Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture. Manalo A, Schroer AK, Fenix AM, Shancer Z, Coogan J, Brolsma T, Burnette DT, Merryman WD, Bader DM., Free PMC Article | 10/12/2019 |
The results establish CENP-F as the first well-characterized Nde1 cargo protein, and reveal phosphorylation control of Nde1 cargo binding throughout a substantial fraction of the cell cycle. | Cdk1 phosphorylation of the dynein adapter Nde1 controls cargo binding from G2 to anaphase. Wynne CL, Vallee RB., Free PMC Article | 09/21/2019 |