| FAT10 induces immune suppression by upregulating PD-L1 expression in hepatocellular carcinoma. | FAT10 induces immune suppression by upregulating PD-L1 expression in hepatocellular carcinoma.
Wang Q, Tan W, Zhang Z, Chen Q, Xie Z, Yang L, Tang C, Zhuang H, Wang B, Jiang J, Ma X, Wang W, Hua Y, Shang C, Chen Y. | 09/23/2024 |
| Cytokines-activated nuclear IKKalpha-FAT10 pathway induces breast cancer tamoxifen-resistance. | Cytokines-activated nuclear IKKα-FAT10 pathway induces breast cancer tamoxifen-resistance.
Chen X, Wu W, Jeong JH, Rokavec M, Wei R, Feng S, Schroth W, Brauch H, Zhong S, Luo JL. | 06/28/2024 |
| The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARalpha. | The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα.
Clavreul L, Bernard L, Cotte AK, Hennuyer N, Bourouh C, Devos C, Helleboid A, Haas JT, Verrijken A, Gheeraert C, Derudas B, Guille L, Chevalier J, Eeckhoute J, Vallez E, Dorchies E, Van Gaal L, Lassailly G, Francque S, Staels B, Paumelle R. | 02/14/2024 |
| UBDP1 pseudogene and UBD network competitively bind miR-6072 to promote glioma progression. | UBDP1 pseudogene and UBD network competitively bind miR‑6072 to promote glioma progression.
Hong F, Gong Z, Chen C, Hua T, Huang Q, Liu Y, Ma P, Zhang X, Wang H, Chen J., Free PMC Article | 02/6/2024 |
| FAT10 differentially stabilizes MYPT2 isoforms. | FAT10 differentially stabilizes MYPT2 isoforms.
Song SE, Kim Y, Jeong H, Lee B, Lee J, Roh JS, So MW, Lee SG, Sohn DH. | 09/6/2023 |
| Tumor necrosis factor mediates USE1-independent FAT10ylation under inflammatory conditions. | Tumor necrosis factor mediates USE1-independent FAT10ylation under inflammatory conditions.
Schnell L, Zubrod A, Catone N, Bialas J, Aichem A., Free PMC Article | 08/28/2023 |
| FAT10 and NUB1L cooperate to activate the 26S proteasome. | FAT10 and NUB1L cooperate to activate the 26S proteasome.
Brockmann F, Catone N, Wünsch C, Offensperger F, Scheffner M, Schmidtke G, Aichem A., Free PMC Article | 05/25/2023 |
| FAT10 Silencing Prevents Liver Fibrosis through Regulating SIRT1 Expression in Hepatic Stellate Cells. | FAT10 Silencing Prevents Liver Fibrosis through Regulating SIRT1 Expression in Hepatic Stellate Cells.
Zheng W, Guan F, Xu G, Yu Y, Xiao J, Huang X., Free PMC Article | 04/17/2023 |
| Ubiquitin D promotes the progression of rheumatoid arthritis via activation of the p38 MAPK pathway. | Ubiquitin D promotes the progression of rheumatoid arthritis via activation of the p38 MAPK pathway.
Chen H, Tao L, Liang J, Pan C, Wei H., Free PMC Article | 01/28/2023 |
| Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFalpha-Stimulated NFkappaB Activity and FAT10 Expression in Human Corneal Epithelial Cells. | Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells.
Menon NG, Suhail Y, Goyal R, Du W, Tanguay AP, Jay GD, Ghosh M, Kshitiz, Schmidt TA., Free PMC Article | 11/19/2022 |
| Identification and Verification of Ubiquitin D as a Gene Associated with Hepatitis C Virus-Induced Hepatocellular Carcinoma. | Identification and Verification of Ubiquitin D as a Gene Associated with Hepatitis C Virus-Induced Hepatocellular Carcinoma.
Li H, Liu S, Lin Y, Shi X, Du N, Yao J, Liu R, Du Y, Yang K., Free PMC Article | 10/29/2022 |
| IDO1, FAT10, IFI6, and GILT Are Involved in the Antiretroviral Activity of gamma-Interferon and IDO1 Restricts Retrovirus Infection by Autophagy Enhancement. | IDO1, FAT10, IFI6, and GILT Are Involved in the Antiretroviral Activity of γ-Interferon and IDO1 Restricts Retrovirus Infection by Autophagy Enhancement.
Kubo Y, Yasui K, Izumida M, Hayashi H, Matsuyama T., Free PMC Article | 08/6/2022 |
| FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression. | FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
Zhu J, Zhao J, Luo C, Zhu Z, Peng X, Zhu X, Lin K, Bu F, Zhang W, Li Q, Wang K, Hu Z, Yu X, Chen L, Yuan R., Free PMC Article | 06/11/2022 |
| Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy. | Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy.
Roverato ND, Sailer C, Catone N, Aichem A, Stengel F, Groettrup M. | 01/29/2022 |
| K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap. | K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap.
van Tilburg GBA, Murachelli AG, Fish A, van der Heden van Noort GJ, Ovaa H, Sixma TK. | 09/4/2021 |
| Ubiquitin-like protein FAT10: A potential cardioprotective factor and novel therapeutic target in cancer. | Ubiquitin-like protein FAT10: A potential cardioprotective factor and novel therapeutic target in cancer.
Zhang K, Chen L, Zhang Z, Cao J, He L, Li L. | 07/24/2021 |
| FAT10: Function and Relationship with Cancer. | FAT10: Function and Relationship with Cancer.
Xiang S, Shao X, Cao J, Yang B, He Q, Ying M. | 07/10/2021 |
| FAT10 promotes the progression of bladder cancer by upregulating HK2 through the EGFR/AKT pathway. | FAT10 promotes the progression of bladder cancer by upregulating HK2 through the EGFR/AKT pathway.
Zou Y, Du Y, Cheng C, Deng X, Shi Z, Lu X, Hu H, Qiu J, Jiang W. | 05/1/2021 |
| Regulation of Interferon Induction by the Ubiquitin-Like Modifier FAT10. | Regulation of Interferon Induction by the Ubiquitin-Like Modifier FAT10.
Mah MM, Roverato N, Groettrup M., Free PMC Article | 04/17/2021 |
| The ubiquitin-like modifier FAT10 inhibits retinal PDE6 activity and mediates its proteasomal degradation. | The ubiquitin-like modifier FAT10 inhibits retinal PDE6 activity and mediates its proteasomal degradation.
Boehm AN, Bialas J, Catone N, Sacristan-Reviriego A, van der Spuy J, Groettrup M, Aichem A., Free PMC Article | 02/27/2021 |
| Molecular recognition of ubiquitin and Lys63-linked diubiquitin by STAM2 UIM-SH3 dual domain: the effect of its linker length and flexibility. | Molecular recognition of ubiquitin and Lys63-linked diubiquitin by STAM2 UIM-SH3 dual domain: the effect of its linker length and flexibility.
Nguyen MH, Martin M, Kim H, Gabel F, Walker O, Hologne M., Free PMC Article | 11/21/2020 |
| Ubiquitin-like protein FAT10 promotes osteosarcoma growth by modifying the ubiquitination and degradation of YAP1. | Ubiquitin-like protein FAT10 promotes osteosarcoma growth by modifying the ubiquitination and degradation of YAP1.
Yi X, Deng X, Zhao Y, Deng B, Deng J, Fan H, Du Y, Hao L. | 10/31/2020 |
| Attenuation of the Innate Immune Response against Viral Infection Due to ZNF598-Promoted Binding of FAT10 to RIG-I. | Attenuation of the Innate Immune Response against Viral Infection Due to ZNF598-Promoted Binding of FAT10 to RIG-I.
Wang G, Kouwaki T, Okamoto M, Oshiumi H. | 09/5/2020 |
| Neither differences in the binding strength to, nor activation by PA28alphabeta, nor a difference in the rate of FAT10-mediated degradation can account for distinct functional capabilities of the IP as compared to the CP. | The 20S immunoproteasome and constitutive proteasome bind with the same affinity to PA28αβ and equally degrade FAT10.
Schmidtke G, Schregle R, Alvarez G, Huber EM, Groettrup M. | 01/25/2020 |
| addition of FAT10 also led to an increased interaction between OTUB1 and its cognate E2 UbcH5B, implying a function of FAT10 in the inhibition of polyubiquitylation | The ubiquitin-like modifier FAT10 stimulates the activity of deubiquitylating enzyme OTUB1.
Bialas J, Boehm AN, Catone N, Aichem A, Groettrup M., Free PMC Article | 12/14/2019 |