| Helicases DDX5 and DDX17 promote heterogeneity in HBV transcription termination in infected human hepatocytes. | Helicases DDX5 and DDX17 promote heterogeneity in HBV transcription termination in infected human hepatocytes.
Chapus F, Giraud G, Huchon P, Rodà M, Grand X, Charre C, Goldsmith C, Roca Suarez AA, Martinez MG, Fresquet J, Diederichs A, Locatelli M, Polvèche H, Scholtès C, Chemin I, Hernandez Vargas H, Rivoire M, Bourgeois CF, Zoulim F, Testoni B. | 09/25/2024 |
| [circDDX17 targets miR-223-3p / RIP3 to regulate the proliferation and apoptosis of non-small cell lung cancer cells]. | [circDDX17 targets miR-223-3p / RIP3 to regulate the proliferation and apoptosis of non-small cell lung cancer cells].
Ding CZ, Wang GL, Jiang GQ, Wang HT, Liu YY, Zhang HL, Sun F, Wei L. | 03/19/2024 |
| LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17. | LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17.
Yao C, Zeng L, Liu Q, Qiu X, Chen C., Free PMC Article | 09/28/2023 |
| DDX17 modulates the expression and alternative splicing of genes involved in apoptosis and proliferation in lung adenocarcinoma cells. | DDX17 modulates the expression and alternative splicing of genes involved in apoptosis and proliferation in lung adenocarcinoma cells.
He C, Zhang G, Lu Y, Zhou J, Ren Z., Free PMC Article | 01/21/2023 |
| MTDH-stabilized DDX17 promotes tumor initiation and progression through interacting with YB1 to induce EGFR transcription in Hepatocellular Carcinoma. | MTDH-stabilized DDX17 promotes tumor initiation and progression through interacting with YB1 to induce EGFR transcription in Hepatocellular Carcinoma.
Jin C, Han-Hua D, Qiu-Meng L, Deng N, Peng-Chen D, Jie M, Lei X, Xue-Wu Z, Hui-Fang L, Yan C, Xiao-Ping C, Bi-Xiang Z. | 01/21/2023 |
| DDX17 induces epithelial-mesenchymal transition and metastasis through the miR-149-3p/CYBRD1 pathway in colorectal cancer. | DDX17 induces epithelial-mesenchymal transition and metastasis through the miR-149-3p/CYBRD1 pathway in colorectal cancer.
Zhao G, Wang Q, Zhang Y, Gu R, Liu M, Li Q, Zhang J, Yuan H, Feng T, Ou D, Li S, Li S, Li K, Mo C, Lin P., Free PMC Article | 01/14/2023 |
| DDX17 helicase promotes resolution of R-loop-mediated transcription-replication conflicts in human cells. | DDX17 helicase promotes resolution of R-loop-mediated transcription-replication conflicts in human cells.
Boleslavska B, Oravetzova A, Shukla K, Nascakova Z, Ibini ON, Hasanova Z, Andrs M, Kanagaraj R, Dobrovolna J, Janscak P., Free PMC Article | 12/24/2022 |
| DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci. | DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci.
Bader AS, Luessing J, Hawley BR, Skalka GL, Lu WT, Lowndes NF, Bushell M., Free PMC Article | 10/22/2022 |
| DDX17-regulated alternative splicing that produced an oncogenic isoform of PXN-AS1 to promote HCC metastasis. | DDX17-regulated alternative splicing that produced an oncogenic isoform of PXN-AS1 to promote HCC metastasis.
Zhou HZ, Li F, Cheng ST, Xu Y, Deng HJ, Gu DY, Wang J, Chen WX, Zhou YJ, Yang ML, Ren JH, Zheng L, Huang AL, Chen J., Free PMC Article | 05/14/2022 |
| DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner. | DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner.
Fortuna TR, Kour S, Anderson EN, Ward C, Rajasundaram D, Donnelly CJ, Hermann A, Wyne H, Shewmaker F, Pandey UB., Free PMC Article | 01/22/2022 |
| RNA Helicase DDX17 Inhibits Hepatitis B Virus Replication by Blocking Viral Pregenomic RNA Encapsidation. | RNA Helicase DDX17 Inhibits Hepatitis B Virus Replication by Blocking Viral Pregenomic RNA Encapsidation.
Mao R, Dong M, Shen Z, Zhang H, Liu Y, Cai D, Mitra B, Zhang J, Guo H., Free PMC Article | 10/16/2021 |
| The Significance of Circular RNA DDX17 in Prostate Cancer. | The Significance of Circular RNA DDX17 in Prostate Cancer.
Lin Q, Cai J, Wang QQ., Free PMC Article | 05/1/2021 |
| CircDDX17 reduces 5-fluorouracil resistance and hinders tumorigenesis in colorectal cancer by regulating miR-31-5p/KANK1 axis. | CircDDX17 reduces 5-fluorouracil resistance and hinders tumorigenesis in colorectal cancer by regulating miR-31-5p/KANK1 axis.
Ren TJ, Liu C, Hou JF, Shan FX. | 03/6/2021 |
| Differential roles of two DDX17 isoforms in the formation of membraneless organelles. | Differential roles of two DDX17 isoforms in the formation of membraneless organelles.
Hirai Y, Domae E, Yoshikawa Y, Tomonaga K. | 02/2/2021 |
| Upregulation of DEAD box helicase 5 and 17 are correlated with the progression and poor prognosis in gliomas. | Upregulation of DEAD box helicase 5 and 17 are correlated with the progression and poor prognosis in gliomas.
Luo Q, Que T, Luo H, Meng Y, Chen X, Huang H, Hu R, Luo K, Zheng C, Yan P, Gong J, Fu H, Liu J, Tang Q, Huang G. | 11/21/2020 |
| DDX17 promotes hepatocellular carcinoma progression via inhibiting Klf4 transcriptional activity. | DDX17 promotes hepatocellular carcinoma progression via inhibiting Klf4 transcriptional activity.
Xue Y, Jia X, Li C, Zhang K, Li L, Wu J, Yuan J, Li Q., Free PMC Article | 08/29/2020 |
| Hypoxia-induced polyubiquitination of DDX17 controls its dissociation from the pri-miRNA-Drosha-DCGR8 complex to reduce anti-stemness miRNA biogenesis and association with YAP and p300 to enhance transcription of stemness-related genes | Regulation of miRNA Biogenesis and Histone Modification by K63-Polyubiquitinated DDX17 Controls Cancer Stem-like Features.
Kao SH, Cheng WC, Wang YT, Wu HT, Yeh HY, Chen YJ, Tsai MH, Wu KJ. | 02/15/2020 |
| Data indicate a central role for DEAD-box helicase 17 (DDX17) in the pathway involving transcription factor REST (REST) and miRNAs that allows neuronal gene repression. | The RNA helicase DDX17 controls the transcriptional activity of REST and the expression of proneural microRNAs in neuronal differentiation.
Lambert MP, Terrone S, Giraud G, Benoit-Pilven C, Cluet D, Combaret V, Mortreux F, Auboeuf D, Bourgeois CF., Free PMC Article | 08/31/2019 |
| The results of qRT-PCR for circDDX17 in 60 paired CRC tissues showed that circDDX17 was significantly down-regulated in CRC tissues and associated with unfavorable clinicopathological parameters. In vitro experiments showed that silencing of circDDX17 promoted CRC cell proliferation, migration, invasion, and inhibited apoptosis. | RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer.
Li XN, Wang ZJ, Ye CX, Zhao BC, Li ZL, Yang Y., Free PMC Article | 01/19/2019 |
| This study demonstrated that the association of DDX17delG in the treatment-resistant ophthalmoplegic subphenotype of myasthenia gravis. | Exome sequencing identifies targets in the treatment-resistant ophthalmoplegic subphenotype of myasthenia gravis.
Nel M, Jalali Sefid Dashti M, Gamieldien J, Heckmann JM. | 05/5/2018 |
| Mutant p53 protein (Mutp53) binds and sequesters RNA helicases p72/82 from microprocessor causing an attenuation of microRNAs (miRNAs) maturation. | Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.
Garibaldi F, Falcone E, Trisciuoglio D, Colombo T, Lisek K, Walerych D, Del Sal G, Paci P, Bossi G, Piaggio G, Gurtner A. | 09/16/2017 |
| DDX17 contributes to acquired gefitinib resistance through exportin/importin-dependent cytoplasmic shuttling and activation of beta-catenin in non-small lung cancer cells. | DDX17 nucleocytoplasmic shuttling promotes acquired gefitinib resistance in non-small cell lung cancer cells via activation of β-catenin.
Li K, Mo C, Gong D, Chen Y, Huang Z, Li Y, Zhang J, Huang L, Li Y, Fuller-Pace FV, Lin P, Wei Y. | 08/26/2017 |
| The miRNA biogenesis factors, DDX17 and KHSRP, regulate the protein level of Ago2 in human cells. | The miRNA biogenesis factors, p72/DDX17 and KHSRP regulate the protein level of Ago2 in human cells.
Connerty P, Bajan S, Remenyi J, Fuller-Pace FV, Hutvagner G. | 06/3/2017 |
| DDX17 is a Sox2-binding protein in estrogen receptor-positive breast cancer; in reporter responsive (RR) cells but not reporter unresponsive (RU) cells, DDX17 enhances the tumorigenic and stem-like features of Sox2 by promoting its binding to its target genes | DDX17 (P72), a Sox2 binding partner, promotes stem-like features conferred by Sox2 in a small cell population in estrogen receptor-positive breast cancer.
Alqahtani H, Gopal K, Gupta N, Jung K, Alshareef A, Ye X, Wu F, Li L, Lai R. | 01/28/2017 |
| Overexpression of p72 decreased Beclin1 expression partially by increasing miR-34-5p and miR-5195-3p expression in glioma cells. | Upregulation of p72 Enhances Malignant Migration and Invasion of Glioma Cells by Repressing Beclin1 Expression.
Zhang Z, Tian H, Miao Y, Feng X, Li Y, Wang H, Song X. | 01/14/2017 |