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Crystal structure of PI3Kgamma with a dihydropurinone inhibitor (compound 18)[SIGNALING PROTEIN]
View in iCn3D Similar StructuresPubMedProteinsConserved DomainsPubChem Compound
NVS-PI3-4 bound to the PI3Kg catalytic subunit p110 gamma[TRANSFERASE/TRANSFERASE Inhibitor]
IPI-549 bound to the PI3Kg catalytic subunit p110 gamma[TRANSFERASE/TRANSFERASE Inhibitor]
Gedatolisib bound to the PI3Kg catalytic subunit p110 gamma[TRANSFERASE]
Crystal structure of PI3Kgamma in complex with DNA-PK inhibitor AZD7648[TRANSFERASE]
Crystal structure of PI3Kgamma with a dihydropurinone inhibitor (compound 4)[TRANSFERASE]
PI3Kg IN COMPLEX WITH Compound 7[TRANSFERASE]
View in iCn3D Similar StructuresProteinsConserved DomainsPubChem Compound
PI3Kg IN COMPLEX WITH INH[HYDROLASE]
PI3Kg IN COMPLEX WITH 5d[TRANSFERASE]
PI3Kg in complex with AZD6482[TRANSFERASE]
Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform[Transferase/Transferase Inhibitor]
Design and Synthesis of a Novel Pyrrolidinyl Pyrido Pyrimidinone Derivative as a Potent Inhibitor of PI3Ka and mTOR[Transferase/Transferase Inhibitor]
Compound 21 (1-alkyl-substituted 1,2,4-triazoles)[Transferase/Transferase Inhibitor]
View in iCn3D Similar StructuresPubMedProteinsConserved Domains
X-ray structure of PI3K-gamma bound to a 4-(morpholin-4-yl)- (6-oxo-1,6-dihydropyrimidin-2-yl)amide inhibitor[Transferase/Transferase Inhibitor]
Potent and Highly Selective Benzimidazole Inhibitors of PI3K-delta[transferase/transferase inhibitor]
Rational Design of PI3K-alpha Inhibitors that Exhibit Selectivity Over the PI3K-beta Isoform[TRANSFERASE/TRANSFERASE INHIBITOR]
Discovery of GDC-0980: a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor for the Treatment of Cancer[TRANSFER...
Fragment based discovery of a novel and selective PI3 Kinase inhibitor[TRANSFERASE]
Fragment Bound to PI3Kinase gamma[TRANSFERASE]
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