ERBB - Structure - NCBI

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Select item 274061.

Molecular Structure Image for 1S78

Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex[TRANSFERASE]

Taxonomy:: Homo sapiens, Mus musculus

Proteins:: 3
Chemicals:: 5
modified:: 2023-08-26

MMDB ID:: 27406
PDB ID:: 1S78

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1025202.

Molecular Structure Image for 4G5P

Crystal Structure Of Egfr Kinase T790m In Complex With Bibw2992[TransferaseTRANSFERASE INHIBITOR, EC: 2.7.10.1]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2012-11-03

MMDB ID:: 102520
PDB ID:: 4G5P

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1025193.

Molecular Structure Image for 4G5J

Crystal Structure Of Egfr Kinase In Complex With Bibw2992[TransferaseTRANSFERASE INHIBITOR, EC: 2.7.10.1]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 3
modified:: 2012-11-03

MMDB ID:: 102519
PDB ID:: 4G5J

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 630954.

Molecular Structure Image for 2R4B

ErbB4 kinase domain complexed with a thienopyrimidine inhibitor[TRANSFERASE]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2024-10-22

MMDB ID:: 63095
PDB ID:: 2R4B

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 344155.

Molecular Structure Image for 2A91

Crystal structure of ErbB2 domains 1-3[SIGNALING PROTEIN,TRANSFERASE,MEMBRANE PROTEIN]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 4
modified:: 2024-10-22

MMDB ID:: 34415
PDB ID:: 2A91

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 166196.

Molecular Structure Image for 1IIJ

SOLUTION STRUCTURE OF THE NEU/ERBB-2 MEMBRANE SPANNING SEGMENT[SIGNALING PROTEIN]

Taxonomy:: synthetic construct

Proteins:: 1
modified:: 2024-05-22

MMDB ID:: 16619
PDB ID:: 1IIJ

View in iCn3D PubMed Proteins

Select item 352107.

Molecular Structure Image for 2AHX

Crystal structure of ErbB4/HER4 extracellular domain[CELL CYCLE,SIGNALING PROTEIN]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 9
modified:: 2018-03-19

MMDB ID:: 35210
PDB ID:: 2AHX

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 220998.

Molecular Structure Image for 1N8Z

Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab[TRANSFERASE]

Taxonomy:: synthetic construct, Homo sapiens

Proteins:: 3
Chemicals:: 3
modified:: 2023-08-21

MMDB ID:: 22099
PDB ID:: 1N8Z

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 825539.

Molecular Structure Image for 2KS1

Heterodimeric association of Transmembrane domains of ErbB1 and ErbB2 receptors Enabling Kinase Activation[TRANSFERASE]

Taxonomy:: Homo sapiens

Proteins:: 2
modified:: 2024-05-01

MMDB ID:: 82553
PDB ID:: 2KS1

View in iCn3D PubMed Proteins Conserved Domains

Select item 13664210.

Molecular Structure Image for 2N2A

Spatial structure of HER2/ErbB2 dimeric transmembrane domain in the presence of cytoplasmic juxtamembrane domains[MEMBRANE PROTEIN]

Taxonomy:: Homo sapiens

Proteins:: 2
modified:: 2024-05-15

MMDB ID:: 136642
PDB ID:: 2N2A

View in iCn3D PubMed Proteins Conserved Domains

Select item 10236411.

Molecular Structure Image for 3U7U

Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex with neuregulin-1 beta[TRANSFERASE/TRANSFERASE REGULATOR]

Taxonomy:: Homo sapiens

Proteins:: 2
Chemicals:: 5
modified:: 2023-09-18

MMDB ID:: 102364
PDB ID:: 3U7U

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 24410212.

Molecular Structure Image for 8U4L

Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain[MEMBRANE PROTEIN, TRANSFERASE]

Taxonomy:: Homo sapiens

Proteins:: 3
Chemicals:: 35
modified:: 2024-09-29

MMDB ID:: 244102
PDB ID:: 8U4L

View in iCn3D Similar Structures PubMed Proteins PubChem Compound

Select item 24410113.

Molecular Structure Image for 8U4K

Structure of the HER2/HER4/BTC Heterodimer Extracellular Domain[MEMBRANE PROTEIN, TRANSFERASE]

Taxonomy:: Homo sapiens

Proteins:: 3
Chemicals:: 35
modified:: 2024-09-29

MMDB ID:: 244101
PDB ID:: 8U4K

View in iCn3D Similar Structures PubMed Proteins PubChem Compound

Select item 20815714.

Molecular Structure Image for 7MN5

Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain[SIGNALING PROTEIN]

Taxonomy:: Homo sapiens, synthetic construct

Proteins:: 3
Chemicals:: 13
modified:: 2021-12-30

MMDB ID:: 208157
PDB ID:: 7MN5

View in iCn3D PubMed Proteins Conserved Domains PubChem Compound

Select item 13172715.

Molecular Structure Image for 4ZJV

crystal structure of EGFR kinase domain in complex with Mitogen-inducible gene 6 protein[TRANSFERASE/INHIBITOR]

Taxonomy:: Homo sapiens

Proteins:: 2
modified:: 2023-11-18

MMDB ID:: 131727
PDB ID:: 4ZJV

View in iCn3D Similar Structures PubMed Proteins Conserved Domains

Select item 13161616.

Molecular Structure Image for 4R3R

Crystal Structures Of Egfr In Complex With Mig6[Transferase, EC: 2.7.10.1]

Taxonomy:: Homo sapiens

Proteins:: 2
modified:: 2015-09-22

MMDB ID:: 131616
PDB ID:: 4R3R

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 13161517.

Molecular Structure Image for 4R3P

Crystal Structures Of Egfr In Complex With Mig6[Transferase, EC: 2.7.10.1]

Taxonomy:: Homo sapiens

Proteins:: 2
modified:: 2015-09-22

MMDB ID:: 131615
PDB ID:: 4R3P

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 20866118.

Molecular Structure Image for 7MN8

Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain bound to Trastuzumab Fab[SIGNALING PROTEIN/IMMUNE SYSTEM]

Taxonomy:: Homo sapiens, synthetic construct

Proteins:: 5
Chemicals:: 13
modified:: 2024-10-29

MMDB ID:: 208661
PDB ID:: 7MN8

View in iCn3D PubMed Proteins Conserved Domains PubChem Compound

Select item 20815819.

Molecular Structure Image for 7MN6

Structure of the HER2 S310F/HER3/NRG1b Heterodimer Extracellular Domain[SIGNALING PROTEIN]

Taxonomy:: Homo sapiens, synthetic construct

Proteins:: 3
Chemicals:: 13
modified:: 2021-12-30

MMDB ID:: 208158
PDB ID:: 7MN6

View in iCn3D PubMed Proteins PubChem Compound

Select item 6798220.

Molecular Structure Image for 3BE1

Dual specific bH1 Fab in complex with the extracellular domain of HER2/ErbB-2[TRANSFERASE]

Taxonomy:: Homo sapiens

Proteins:: 3
Chemicals:: 3
modified:: 2023-09-06

MMDB ID:: 67982
PDB ID:: 3BE1

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

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Protein Domain Families

Families (315)
Structures with functionally specific protein families
Superfamilies (338)
Structures with evolutionary related protein superfamilies

Complexes

Protein-Protein (177)
Structures containing multiple proteins
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ERBB (419)
Structure
ELMO domain-containing protein 3 isoform a [Homo sapiens]
ELMO domain-containing protein 3 isoform a [Homo sapiens]
gi|21362032|ref|NP_115589.2|

Protein
calmodulin-binding transcription activator 2 isoform X8 [Mus musculus]
calmodulin-binding transcription activator 2 isoform X8 [Mus musculus]
gi|1720365366|ref|XP_030101691.1|

Protein

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