GSM4684951: GBM019_P3n6 [239115]; Homo sapiens; RNA-Seq - SRA

SRX8805961: GSM4684951: GBM019_P3n6 [239115]; Homo sapiens; RNA-Seq
3 ILLUMINA (Illumina HiSeq 4000) runs: 44.3M spots, 6.6G bases, 2.3Gb downloads

Submitted by: NCBI (GEO)

Study: Comparative analysis of glioblastoma initiating cells and patient-matched EPSC-derived neural stem cells as a discovery tool and drug matching strategy [RNA-Seq]

PRJNA648056 • SRP273245 • All experiments • All runs

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Malignant gliomas are the most common intrinsic brain tumours in adults and are associated with a very poor prognosis, which has not improved in the last 20 years. We show here that glioblastoma initiating cells (GIC) and syngeneic neural stem cells derived from enhanced pluripotent stem cells (iNSC) are a suitable novel pre-clinical pipeline to discover new patient-specific disease mechanisms and to identify druggable targets for personalised therapy. Overall design: Transcriptomic data of human dura mater fibroblasts, iPSC, iNSC, GIC and FFPE bulk tumour

Sample: GBM019_P3n6 [239115]

SAMN15617972 • SRS7072163 • All experiments • All runs

Organism: Homo sapiens

Library:

Instrument: Illumina HiSeq 4000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: PAIRED

Construction protocol: RNA was extracted from cell pellets using the RNA/DNA/Protein Purification Plus kit (NORGEN, #47700), following the manufactured protocol. Human RNA samples were sequenced on HiSeq4000, at 75 PE after polyA selection, by Oxford Genomics Centre

Experiment attributes:

GEO Accession: GSM4684951

Links:

NCBI link: NCBI Entrez (gds)

Runs: 3 runs, 44.3M spots, 6.6G bases, 2.3Gb

Run	# of Spots	# of Bases	Size	Published
SRR12302972	15,038,227	2.3G	825.1Mb	2021-09-18
SRR12302973	14,669,472	2.2G	786.2Mb	2021-09-18
SRR12302974	14,621,920	2.2G	772.6Mb	2021-09-18

ID:: 11448486

SRA

Sequence Read Archive

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