GSM4684923: DURA026_NSC_N31D_P5 [214162]; Homo sapiens; RNA-Seq - SRA

SRX8805933: GSM4684923: DURA026_NSC_N31D_P5 [214162]; Homo sapiens; RNA-Seq
2 ILLUMINA (Illumina HiSeq 4000) runs: 59.9M spots, 9G bases, 3.4Gb downloads

Submitted by: NCBI (GEO)

Study: Comparative analysis of glioblastoma initiating cells and patient-matched EPSC-derived neural stem cells as a discovery tool and drug matching strategy [RNA-Seq]

PRJNA648056 • SRP273245 • All experiments • All runs

show Abstracthide Abstract

Malignant gliomas are the most common intrinsic brain tumours in adults and are associated with a very poor prognosis, which has not improved in the last 20 years. We show here that glioblastoma initiating cells (GIC) and syngeneic neural stem cells derived from enhanced pluripotent stem cells (iNSC) are a suitable novel pre-clinical pipeline to discover new patient-specific disease mechanisms and to identify druggable targets for personalised therapy. Overall design: Transcriptomic data of human dura mater fibroblasts, iPSC, iNSC, GIC and FFPE bulk tumour

Sample: DURA026_NSC_N31D_P5 [214162]

SAMN15618024 • SRS7072136 • All experiments • All runs

Organism: Homo sapiens

Library:

Instrument: Illumina HiSeq 4000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: PAIRED

Construction protocol: RNA was extracted from cell pellets using the RNA/DNA/Protein Purification Plus kit (NORGEN, #47700), following the manufactured protocol. Human RNA samples were sequenced on HiSeq4000, at 75 PE after polyA selection, by Oxford Genomics Centre

Experiment attributes:

GEO Accession: GSM4684923

Links:

NCBI link: NCBI Entrez (gds)

Runs: 2 runs, 59.9M spots, 9G bases, 3.4Gb

Run	# of Spots	# of Bases	Size	Published
SRR12302907	29,978,412	4.5G	1.8Gb	2021-09-18
SRR12302908	29,966,727	4.5G	1.6Gb	2021-09-18

ID:: 11448458

SRA

Sequence Read Archive

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