show Abstracthide AbstractThe growth factor, TGF-beta can have profound effect on global gene expression changes. Since TGF-beta signaling is not well studied in liver epithelia, RNA-seq analysis was performed to evaluate TGF-beta signaling in cholangiocytes. Overall design: Cholangiocyte cell line, HIBEC, were treated with Vehicle or TGF-beta for 48 hours to look at the gene expresson changes induced by TGF-beta